CAS No.: 485-72-3
刺芒柄花素 Catalog No. CSN12349
Synonyms: 刺芒柄花素;Biochanin B;Flavosil
Formononetin can act as an agonist of aryl hydrocarbon receptor (EC50 = 130 nM) and has prevention of breast cancer, prostate cancer and colon cancer. Formononetin could be extracted from the bark of Ononis natrix L..
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02174666 Osteopenia Os... more >>teoporosis Collapse << Not Applicable Unknown September 2016 Denmark ... more >> Aarhus University Hospital Aarhus, Central Jutland Region, Denmark, 8000 Collapse << NCT01497977 Low Serum Lipid Levels Phase 4 Completed - Serbia ... more >> Ultramedica Clinic, American Medical Academy Belgrade, Serbia, 11000 Collapse << - 参考文献
- [1] Zhang X, Bi L, et al. Formononetin induces apoptosis in PC-3 prostate cancer cells through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt pathway. Nutr Cancer. 2014;66(4):656-61.
- [2] Chen J, Zeng J, et al. Formononetin induces cell cycle arrest of human breast cancer cells via IGF1/PI3K/Akt pathways in vitro and in vivo. Horm Metab Res. 2011 Sep;43(10):681-6.
- [3] Huang D, Wang C, Duan Y, Meng Q, Liu Z, Huo X, Sun H, Ma X, Liu K. Targeting Oct2 and P53: Formononetin prevents cisplatin-induced acute kidney injury. Toxicol Appl Pharmacol. 2017 Jul 1;326:15-24. doi: 10.1016/j.taap.2017.04.013. Epub 2017 Apr 13. Erratum in: Toxicol Appl Pharmacol. 2022 Sep 1;450:116133. PMID: 28414026.
- [4] El-Bakoush A, Olajide OA. Formononetin inhibits neuroinflammation and increases estrogen receptor beta (ERβ) protein expression in BV2 microglia. Int Immunopharmacol. 2018 Aug;61:325-337. doi: 10.1016/j.intimp.2018.06.016. Epub 2018 Jun 15. PMID: 29913427.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 485-72-3 | 储存条件 |
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| 分子式 | C16H12O4 | 运输 | 蓝冰 | |||||
| 分子量 | 268.26 | 别名 | 刺芒柄花素;Biochanin B;Flavosil;Formononetol | |||||
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动物实验配方 |
