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CAS No.: 551-16-6

6-Aminopenicillanic acid/6-氨基青霉烷酸 Catalog No. CSN12773

Synonyms: 6-APA;6-Aminopenicillanic Acid;(+)-6-Aminopenicillanic Acid

6-APA is the core moiety of penicillins.

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实验方案

技术信息

生物活性

描述6-APA (6-aminopenicillanic acid), is used to prepare raw materials for semi synthetic penicillin. In the fermentation broth of P. chrysogenum it is necessary to distinguish between the primary 6-APA which is a product of the biosynthesis via L-cystine/D-valine and the secondary 6-APA which originates from isopenicillin N^[2]. The overall yield of 6-APA crystals obtained after enzymatic conversion of penicillin G ranged between 37-55 and 47-68% in foreign and local strains, respectively^[3]. Moreover, 6-APA slightly reduced the exogenous acetylcholine-induced contractile response and this effect was a little weaker than it is on the intramural electrical stimulation-induced contractile response^[4]. Combinations of mecillinam and 6-APA with ampicillin acted synergistically against the gram-negative bacilli^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.6241 mL
- 23.1206 mL
- 46.2412 mL
- 5 mM
- 0.9248 mL
- 4.6241 mL
- 9.2482 mL
- 10 mM
- 0.4624 mL
- 2.3121 mL
- 4.6241 mL

技术信息

CAS号

551-16-6

储存条件

粉末: Keep in dark place,Inert atmosphere,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C8H12N2O3S

运输

蓝冰

分子量

216.26

别名

6-APA;6-Aminopenicillanic Acid;(+)-6-Aminopenicillanic Acid;6β-Aminopenicillanic Acid;NSC 50071;6-氨基青霉烷酸

溶解度

DMSO	1.0 mg/mL (4.6 mM)
Water	Insoluble
Ethanol	Insoluble

动物实验配方

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