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CAS No.: 499-75-2

香芹酚 Catalog No. CSN12683

Synonyms: cymophenol;Isopropyl o-cresol;NSC 6188

Carvacrol exhibits potent antibacterial activity against Salmonella typhimurium, it's a natural product isolated and purified from the herbs of Elsholtzia ciliata diverse activities.

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400-920-2911

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技术信息

生物活性

描述Carvacrol is the major constituent of essential oils derived from plants. It exhibits antimicrobial, antioxidant, anticancer, anti-inflammatory, and anticholinesterase activity^[3]. Carvacrol is a monoterpenoid phenol and majorly present in the essential oils of Lamiaceae family plants. Carvacrol treatment significantly reduced the cell viability of PC-3 cells in a dose- and time-dependent manner. Carvacrol prevented cell cycle in G0/G1 that was associated with decline in expression of cyclin D1 and Cyclin-Dependent Kinase 4 (CDK4) and augmented expression of CDK inhibitor p21^[4]. Moreover, carvacrol largely reduced the asymmetrical use of the forelimbs induced by unilateral 6-hydroxy-dopamine. Carvacrol dramatically reduced the loss of tyrosine hydroxylase immunostaining both in the substantia nigra and in the striatum that are typical of the model. Carvacrol promotes a marked neuroprotection in the 6-hydroxy-dopamine model of Parkinson's disease^[5]. Carvacrol provides protection for hippocampal neurons against I/R in gerbils by inhibiting ferroptosis through increasing the expression of GPx4^[6].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 6.6569 mL
- 33.2845 mL
- 66.5690 mL
- 5 mM
- 1.3314 mL
- 6.6569 mL
- 13.3138 mL
- 10 mM
- 0.6657 mL
- 3.3285 mL
- 6.6569 mL

技术信息

CAS号

499-75-2

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C10H14O

运输

蓝冰

分子量

150.22

别名

cymophenol;Isopropyl o-cresol;NSC 6188;p-Cymen-2-ol;Antioxine;BRN-1860514;Karvakrol;香芹酚;香荆芥酚

溶解度

DMSO	95.0 mg/mL (632.4 mM) warming

动物实验配方

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