CAS No.: 31721-94-5
5,7-Dihydroxychromone/5,7-二羟基色酮 Catalog No. CSN13049
Synonyms: DHC;5,7-Dihydroxy-4H-Chromen-4-One;5,7-二羟基色酮
5,7-Dihydroxychromone, a natural product isolated and purified from the bark of Garcinia cambogia., exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal, and induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Kim DW, Lee KT, et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway. Life Sci. 2015 Jun 1;130:25-30.
- [2] Koo HJ, Kwak JH, Kang SC. Anti-diabetic properties of Daphniphyllum macropodum fruit and its active compound. Biosci Biotechnol Biochem. 2014;78(8):1392-401.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 31721-94-5 | 储存条件 |
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| 分子式 | C9H6O4 | 运输 | 蓝冰 | |
| 分子量 | 178.14 | 别名 | DHC;5,7-Dihydroxy-4H-Chromen-4-One;5,7-二羟基色酮 |
