|4-烯丙基-2-甲氧基苯酚|CsnPharm

CAS No.: 97-53-0

丁香酚 Catalog No. CSN10972

Synonyms: 4-Allyl-2-methoxyphenol;4-Allylguaiacol;Eugenic acid

Eugenol is a natural product used as a local antiseptic and anaesthetic. It is also used in perfumes, flavorings, and essential oils.

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靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Eugenol is a phenolic compound from the class of phenylpropanoids and the main component of clove^[3]. Eugenol and its related compounds are effective antioxidants that can prevent free radical-mediated diseases^[4]. Eugenol's ability to sequester free radicals in the DPPH assay (IC50 = 11.7 μg/mL), as well as to inhibit reactive oxygen species (ROS) (IC50 = 1.6 μg/mL), H2O2 (IC50 = 22.6 μg/mL and 27.1 μg/mL), and NO (IC50< 50.0 μg/mL)^[3].in vitro,the fluorescence of eugenol decreased with the increase of insulin concentration. The values of Ksv and kq were found to be 2.5 × 105 L mol−1 and 2.5 × 1013 L mol−1 s−1 respectively^[5].
临床研究

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参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 6.0901 mL
- 30.4507 mL
- 60.9013 mL
- 5 mM
- 1.2180 mL
- 6.0901 mL
- 12.1803 mL
- 10 mM
- 0.6090 mL
- 3.0451 mL
- 6.0901 mL

技术信息

CAS号

97-53-0

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C10H12O2

运输

蓝冰

分子量

164.20

别名

4-Allyl-2-methoxyphenol;4-Allylguaiacol;Eugenic acid;Allylguaiacol;NSC-209525;丁香酚

溶解度

DMSO	100.0 mg/mL (609.0 mM)

动物实验配方

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02346227	Uterine Cervical Dysplasia ... more >> Papillomavirus Infections Collapse <<	Phase 3	Completed	-	Congo, The Democratic Republic... more >> of the Centre de Santé Lisungi Kinshasa, Mont-Ngafula, Congo, The Democratic Republic of the, Route Kimwenza n°23 Collapse <<
NCT03166748	Pulpotomy of Immature Lower Fi... more >>rst Molar(Apexegenesis) Collapse <<	Not Applicable	Not yet recruiting	August 2018	-
NCT02652403	Edentulous	Phase 2	Completed	-	-
NCT02393326	Pulpotomy Too... more >>th, Deciduous Collapse <<	Not Applicable	Withdrawn(technical and fundin... more >>g issues) Collapse <<	January 2020	-
NCT03397875	Apical Periodontitis	Not Applicable	Completed	-	India ... more >> Post Graduate Institute of Dental Sciences Rohtak, Haryana, India, 124001 Collapse <<
NCT01312194	Periapical Periodontitis	Not Applicable	Completed	-	Brazil ... more >> Federal University of Rio de Janeiro Rio de Janeiro, Brazil, 21941-913 Collapse <<
NCT01622153	Reversible Pulpitis ... more >> Caries Collapse <<	Not Applicable	Terminated(Use of Formocresol ... more >>for pulpotomies ws discontinued.) Collapse <<	-	United States, Ohio ... more >> University Hospital-Rainbow Babies & Children's Hospital Cleveland, Ohio, United States, 44106 Collapse <<
NCT02630745	Attachment Loss ... more >> Tooth,Non Vital Collapse <<	Not Applicable	Completed	-	-
NCT01728532	Root Canal Obturation	Not Applicable	Completed	-	France ... more >> Cabinet dentaire privé - 21, rue Fabre d'Églantine Paris, France Service d'endodontie de la Pitié Salpêtrière Hôpital de la Pitié Salpêtrière Paris, France United Kingdom School of Dentistry Cardiff University Cardiff, United Kingdom Collapse <<
NCT02956174	Single Tooth Lost	Not Applicable	Completed	-	-
NCT00972556	Dental Caries ... more >> Pulpitis Collapse <<	Not Applicable	Unknown	July 2014	Taiwan ... more >> Department of Dentistry, National Taiwan University Hospital Recruiting Taipei, Taiwan, 10048 Contact: Yuan-Ling Lee, PhD yuanlinglee@ntu.edu.tw Contact: Hsiao-Hua Chang, MS hhchangpedo@gmail.com Principal Investigator: Yuan-Ling Lee, PhD Sub-Investigator: Hsiao-Hua Chang, MS Collapse <<
NCT03741894	Alveolitis of Jaw ... more >> Alveoli, Teeth; Inflammation Dry Socket Impacted Third Molar Tooth Collapse <<	Phase 4	Recruiting	September 30, 2021	Hungary ... more >> Department of Oral and Maxillofacial Surgery, University of Pécs Recruiting Pécs, Hungary, 7621 Contact: Jozsef Szalma, DMD, PhD +3672535924 drszalma@freemail.hu Principal Investigator: Jozsef Szalma, DMD, PhD Sub-Investigator: Laszlo Vajta, DMD Principal Investigator: Balázs Soós, DMD Sub-Investigator: Kata Janovics, DMD Collapse <<
NCT03687047	Edentulous Jaw ... more >> Quality of Life Collapse <<	Not Applicable	Recruiting	December 1, 2019	Brazil ... more >> Livia Azeredo Alves Antunes Recruiting Rio De Janeiro, Friburgo, Brazil Contact: LIVIA F ANTUNES, 3 55-21-987151919 LIVIAAZEREDO@GMAIL.COM Collapse <<
NCT01010451	Inflammation ... more >>Necrosis Collapse <<	Phase 4	Completed	-	Brazil ... more >> Dental School Goiânia, Goiás, Brazil, 74605220 Collapse <<
NCT02201498	Deep Dental Caries	Not Applicable	Completed	-	Canada, Quebec ... more >> CHU Sainte-Justine Montreal, Quebec, Canada, h3t1c5 Collapse <<
NCT03650036	Dental Pulp Necrosis	Phase 2	Recruiting	June 4, 2021	Brazil ... more >> Federal University of Piaui Recruiting Teresina, Piaui, Brazil, 64.049-550 Contact: Lúcia Moura, Professor +55-086 3237 1517 mouraiso@uol.com.br Contact: Marina Lima, Professor +55-086 3237 1517 mdmlima@gmail.com Collapse <<
NCT03472456	-	-	Recruiting	April 2019	France ... more >> Les Hôpitaux Universitaires de Strasbourg Recruiting Strasbourg, France, 67091 Contact: Damien OFFNER 03 88 11 69 76 damien.offner@chru-strasbourg.fr Sub-Investigator: Anne-Marie MUSSET Sub-Investigator: Gabriel FERNANDEZ DE GRADO Collapse <<
NCT03437655	MTA Dental Re... more >>storation, Temporary Collapse <<	Not Applicable	Not yet recruiting	October 30, 2018	Brazil ... more >> Federal University of Uberlandia Uberlandia, Minas Gerais, Brazil, 381440617 Collapse <<

丁香酚 Catalog No. CSN10972

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