|3-(3,4-二羟基苯基)丙烯酸|CsnPharm

CAS No.: 331-39-5

咖啡酸 Catalog No. CSN10424

Synonyms: 咖啡酸

Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound isolated and purified from the herb of Boehmeria siamensis Craib., with antioxidant, antineoplastic, anti-HIV, choleretic, hepatotropic, and is a strong inhibitor of neutrophil elastase.

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靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound isolated and purified from the herb of Boehmeria siamensis Craib., with antioxidant, antineoplastic, anti-HIV, choleretic, hepatotropic, and is a strong inhibitor of neutrophil elastase.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00065715	Common Cold	Phase 3	Completed	-	United States, Wisconsin ... more >> University of Wisconsin-Madison Department of Family Medicine Madison, Wisconsin, United States, 53706-1490 Collapse <<
NCT02050334	Healthy	Phase 1	Completed	-	United States, Indiana ... more >> IU Health Neuroscience Center Indianapolis, Indiana, United States, 46202 Collapse <<
NCT02050334	-	-	Completed	-	-

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参考文献

[1] Sirota R, Gibson D, Kohen R. The role of the catecholic and the electrophilic moieties of caffeic acid in Nrf2/Keap1 pathway activation in ovarian carcinoma cell lines. Redox Biol. 2015;4:48-59.
[2] Rosendahl AH, Perks CM, et al. Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer. Clin Cancer Res. 2015 Apr 15;21(8):1877-87.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 5.5507 mL
- 27.7535 mL
- 55.5070 mL
- 5 mM
- 1.1101 mL
- 5.5507 mL
- 11.1014 mL
- 10 mM
- 0.5551 mL
- 2.7754 mL
- 5.5507 mL

技术信息

CAS号

331-39-5

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C9H8O4

运输

蓝冰

分子量

180.16

别名

咖啡酸

溶解度

DMSO	35.0 mg/mL (194.3 mM)
Water	Insoluble
Ethanol	Insoluble

动物实验配方

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT00065715	Common Cold	Phase 3	Completed	-	United States, Wisconsin ... more >> University of Wisconsin-Madison Department of Family Medicine Madison, Wisconsin, United States, 53706-1490 Collapse <<
NCT02050334	Healthy	Phase 1	Completed	-	United States, Indiana ... more >> IU Health Neuroscience Center Indianapolis, Indiana, United States, 46202 Collapse <<
NCT02050334	-	-	Completed	-	-
NCT02744703	Matrix Metalloproteinase Inhib... more >>itors Composite Resins Collapse <<	Not Applicable	Completed	-	-
NCT03049046	Amyotrophic Lateral Sclerosis	Phase 1	Recruiting	March 30, 2018	United States, Indiana ... more >> Indiana University, IU Health Physicians Neurology Recruiting Indianapolis, Indiana, United States, 46202 Contact: Sandra Guingrich, LPN, CCRC 317-963-7382 sguingri@iu.edu Principal Investigator: Robert Pascuzzi, MD Collapse <<
NCT02351622	Immune Thrombocytopenia	Phase 3	Completed	-	China, Shandong ... more >> Shandong University Qilu hospital Jinan, Shandong, China, 250012 Collapse <<
NCT03070262	Esophagus Cancer	Phase 3	Enrolling by invitation	December 2020	China, Henan ... more >> The Clinical Medical College, The First Affiliated Hospital of Henan University of Science and Technology Luoyang, Henan, China, 471003 Collapse <<
NCT02556814	Immune Thrombocytopenia	Phase 4	Unknown	September 2017	China, Shandong ... more >> Qilu Hospital, Shandong University Recruiting Jinan, Shandong, China Contact: Ming Hou, Dr. +86-531-82169114 ext 9879 houming@medmail.com.cn Principal Investigator: Ming Hou, Dr. Collapse <<

咖啡酸 Catalog No. CSN10424

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