CAS No.: 475085-57-5
2-(4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetic acid Catalog No. CSN16760
Synonyms: ACT-333679
MRE-269 can act as an agonist of IP receptor and it is an active metabolite of selexipag.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Fuchikami C, Murakami K, et al. A comparison of vasodilation mode among selexipag (NS-304; [2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino] butoxy}-N-(methylsulfonyl)acetamide] ), its active metabolite MRE-269 and various prostacyclin receptor agonists in rat, porcine and human pulmonary arteries. Eur J Pharmacol. 2017 Jan 15;795:75-83.
- [2] Orie NN, Ledwozyw A, et al. Differential actions of the prostacyclin analogues treprostinil and iloprost and the selexipag metabolite, MRE-269 (ACT-333679) in rat small pulmonary arteries and veins. Prostaglandins Other Lipid Mediat. 2013 Oct;106:1-7.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 475085-57-5 | 储存条件 |
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| 分子式 | C25H29N3O3 | 运输 | 蓝冰 | |||||
| 分子量 | 419.52 | 别名 | ACT-333679 | |||||
| 溶解度 |
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动物实验配方 |
