CAS No.: 120014-06-4
多奈哌齐 Catalog No. CSN16651
Synonyms: E2020 free base;E2020;HSDB-7743
Donepezil is a centrally acting reversible AchE inhibitor with IC50 of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively, a medication used to treat Alzheimer's disease.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
靶点 AChE
IC50:11.6nMAChE (bovine)
IC50:8.12nM- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03055741 Mild-moderate Alzheimer's Dise... more >>ase Collapse << Phase 2 Active, not recruiting June 2019 Korea, Republic of ... more >> The Catholic University of Korea, Bucheon, ST. Mary's Hospital Bucheon-si, Gyeonggi-do, Korea, Republic of Myongji Hospital Goyang-si, Gyeonggi-do, Korea, Republic of Seoul National University Bundang Hospital Seongnam-si, Gyeonggi-do, Korea, Republic of Ajou University Medical Center Suwon-si, Gyeonggi-do, Korea, Republic of Chonnam National University Hospital Gwangju-si, Jeollanam-do, Korea, Republic of Dong-A University Hospital Busan, Korea, Republic of Yeungnam University Medical Center Daegu, Korea, Republic of Daejeon Eulji Medical Center Daejeon, Korea, Republic of, 35233 Hanyang University Guri Hospital Guri-si, Korea, Republic of Gachon University Gil Medical Center Incheon, Korea, Republic of Inha University Hospital Incheon, Korea, Republic of Chung-ang University Hospital Seoul, Korea, Republic of, 06973 Hanyang University Medical Center Seoul, Korea, Republic of Korea University Anam Hospital Seoul, Korea, Republic of The Catholic University of Korea, Seoul ST. Mary's Hospital Seoul, Korea, Republic of Collapse << NCT01276080 Healthy Phase 1 Completed - United States, Nevada ... more >> Novum Pharmaceutical Research Services Las Vegas, Nevada, United States, 89121 Collapse << NCT00566501 Alzheimer's Disease Phase 3 Completed - United States, California ... more >> Apex Research Institute Santa Ana, California, United States, 92705 Collapse << - 更多
- 参考文献
- [1] Ogura H, Kosasa T, et al. Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol. 2000 Oct;22(8):609-13.
- [2] Snape MF, Misra A, et al. A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology. 1999 Jan;38(1):181-93.
- [3] Haraguchi Y, Mizoguchi Y, Ohgidani M, Imamura Y, Murakawa-Hirachi T, Nabeta H, Tateishi H, Kato TA, Monji A. Donepezil suppresses intracellular Ca2+ mobilization through the PI3K pathway in rodent microglia. J Neuroinflammation. 2017 Dec 22;14(1):258. doi: 10.1186/s12974-017-1033-0. PMID: 29273047; PMCID: PMC5741946.
- [4] Li K, Cheng N, Li XT. Inhibitory effects of cholinesterase inhibitor donepezil on the Kv1.5 potassium channel. Sci Rep. 2017 Feb 13;7:41509. doi: 10.1038/srep41509. PMID: 28198801; PMCID: PMC5304190.
- [5] Yu TS, Kim A, Kernie SG. Donepezil rescues spatial learning and memory deficits following traumatic brain injury independent of its effects on neurogenesis. PLoS One. 2015 Feb 25;10(2):e0118793. doi: 10.1371/journal.pone.0118793. PMID: 25714524; PMCID: PMC4340948.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 120014-06-4 | 储存条件 |
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| 分子式 | C24H29NO3 | 运输 | 蓝冰 | |||
| 分子量 | 379.49 | 别名 | E2020 free base;E2020;HSDB-7743;多奈哌齐 | |||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT03055741 | Mild-moderate Alzheimer's Dise... more >>ase Collapse << | Phase 2 | Active, not recruiting | June 2019 | Korea, Republic of ... more >> The Catholic University of Korea, Bucheon, ST. Mary's Hospital Bucheon-si, Gyeonggi-do, Korea, Republic of Myongji Hospital Goyang-si, Gyeonggi-do, Korea, Republic of Seoul National University Bundang Hospital Seongnam-si, Gyeonggi-do, Korea, Republic of Ajou University Medical Center Suwon-si, Gyeonggi-do, Korea, Republic of Chonnam National University Hospital Gwangju-si, Jeollanam-do, Korea, Republic of Dong-A University Hospital Busan, Korea, Republic of Yeungnam University Medical Center Daegu, Korea, Republic of Daejeon Eulji Medical Center Daejeon, Korea, Republic of, 35233 Hanyang University Guri Hospital Guri-si, Korea, Republic of Gachon University Gil Medical Center Incheon, Korea, Republic of Inha University Hospital Incheon, Korea, Republic of Chung-ang University Hospital Seoul, Korea, Republic of, 06973 Hanyang University Medical Center Seoul, Korea, Republic of Korea University Anam Hospital Seoul, Korea, Republic of The Catholic University of Korea, Seoul ST. Mary's Hospital Seoul, Korea, Republic of Collapse << |
| NCT01276080 | Healthy | Phase 1 | Completed | - | United States, Nevada ... more >> Novum Pharmaceutical Research Services Las Vegas, Nevada, United States, 89121 Collapse << |
| NCT00566501 | Alzheimer's Disease | Phase 3 | Completed | - | United States, California ... more >> Apex Research Institute Santa Ana, California, United States, 92705 Collapse << |
| NCT00566501 | - | - | Completed | - | - |
| NCT00165763 | Vascular Dementia | Phase 4 | Completed | - | Philippines ... more >> Memory Center Quezon, Manila, Philippines Subic Bay Medical Center Olongapo, Zambales, Philippines Collapse << |
| NCT00868010 | Ischemic Stroke | Phase 3 | Unknown | November 2013 | United States, Ohio ... more >> Hillside Rehabilitation Hospital Not yet recruiting Warren, Ohio, United States, 44484 Contact: Nancy Landgraff, PhD 330-941-2703 nlandgra@cc.ysu.edu Principal Investigator: Nancy Landgraff, PhD United States, Pennsylvania University of Pittsburgh Medical Center Recruiting Pittsburgh, Pennsylvania, United States, 15213 Contact: Kara Kenton 412-246-5815 kentonkd@upmc.edu Sub-Investigator: Howard Aizenstein, MD, PhD Principal Investigator: Ellen M Whyte, MD Sub-Investigator: Meryl Butters, PhD Sub-Investigator: Ariel Gildengers, MD Sub-Investigator: Jordan Karp, MD Sub-Investigator: Oscar Lopez, MD Sub-Investigator: Sati Mazumdar, MD Sub-Investigator: Michael Munin, MD Sub-Investigator: Charles Reynolds, MD Sub-Investigator: Elizabeth Skidmore, PhD Collapse << |
| NCT01404169 | Alzheimer's Type Dementia | Phase 3 | Completed | - | - |
| NCT00711204 | Severe Alzheimer's Disease | Phase 4 | Withdrawn(No patients were enr... more >>olled in the study.) Collapse << | - | United States, Ohio ... more >> Kettlie Joseph Daniels, M.D. Inc. Toledo, Ohio, United States, 43609 Collapse << |
| NCT00571064 | Mild to Severe Alzheimer's Dis... more >>ease Collapse << | Phase 4 | Completed | - | - |
| NCT00571064 | - | - | Completed | - | - |
| NCT00452868 | - | - | Completed | - | - |
| NCT01327859 | Parkinson's Disease ... more >> Dementia Collapse << | Phase 3 | Completed | - | United Kingdom ... more >> Bath, Canterbury, United Kingdom, BA2 5RP Collapse << |
| NCT01276067 | Healthy | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Novum Pharmaceutical Research Services Pittsburgh,, Pennsylvania, United States Collapse << |
| NCT00452868 | Brain and Central Nervous Syst... more >>em Tumors Cognitive/Functional Effects Long-term Effects Secondary to Cancer Therapy in Children Neurotoxicity Psychosocial Effects of Cancer and Its Treatment Radiation Toxicity Collapse << | Early Phase 1 | Completed | - | United States, Massachusetts ... more >> Tufts-NEMC Cancer Center Boston, Massachusetts, United States, 02111 United States, North Carolina Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 Collapse << |
| NCT02450786 | Parkinson's Disease | Phase 2 | Unknown | March 2018 | Korea, Republic of ... more >> Severance Hospital Recruiting Seoul, Korea, Republic of, 120-752 Contact: Young Ho Sohn, MD, PhD 82-2-2228-1601 yhsohn62@yuhs.ac Collapse << |
| NCT02206620 | Parkinson's Disease | Phase 2 | Unknown | December 2017 | United States, Oregon ... more >> Oregon Health & Science University Recruiting Portland, Oregon, United States, 97239-3098 Contact: Andrew Fraser, BS 503-418-4387 frasean@ohsu.edu Principal Investigator: John Nutt, MD Collapse << |
| NCT02094053 | Down Syndrome | Phase 2 | Completed | - | Japan ... more >> Fukuoka-shi, Fukuoka, Japan Sapporo-shi, Hokkaido, Japan Yokohama-shi, Kanagawa, Japan Takatsuki-shi, Kyoto, Japan Matsumoto-shi, Nagano, Japan Nagasaki-shi, Nagasaki, Japan Izumi-shi, Osaka, Japan Saitama-shi, Saitama, Japan Chiyoda-ku, Tokyo, Japan Setagaya-ku, Tokyo, Japan Collapse << |
| NCT02162264 | - | - | Completed | - | Japan ... more >> Multiple Locations, Japan Collapse << |
| NCT00754052 | Down Syndrome ... more >> Cognitive Dysfunction Collapse << | Phase 3 | Terminated(Sufficient evidence... more >> of efficacy not met. Discontinuation not based on any safety concerns.) Collapse << | - | United States, Texas ... more >> Road Runner Research San Antonio, Texas, United States, 78258 United States, Virginia Neuroscience, Inc Herndon, Virginia, United States, 20170 Collapse << |
| NCT00754052 | - | - | Terminated(Sufficient evidence... more >> of efficacy not met. Discontinuation not based on any safety concerns.) Collapse << | - | - |
| NCT01276353 | Alzheimer's Type Dementia | Phase 2 | Completed | - | Japan ... more >> Kitakyushu, Fukuoka, Japan Mizunami, Gifu, Japan Yokosuka, Kanagawa, Japan Sanjo, Niigata, Japan Kurashiki, Okayama, Japan Fuji, Shizuoka, Japan Hachioji, Tokyo, Japan Kodaira, Tokyo, Japan Akita, Japan Fukuoka, Japan Saitama, Japan Collapse << |
| NCT00505167 | Dementia, Alzheimer Type | Phase 4 | Completed | - | Spain ... more >> Hospital de Barbastro Barbastro, Huesca, Spain, 50508 Cenro de especialidades San José. Hospital Miguel Servet Zaragoza, Spain, 50008 Hospital Royo Villanova Zaragoza, Spain Collapse << |
| NCT01276353 | - | - | Completed | - | - |
| NCT00047697 | - | - | Completed | - | - |
| NCT00987220 | - | - | Completed | - | United States, Connecticut ... more >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511 Collapse << |
| NCT02162251 | - | - | Completed | - | Japan ... more >> Multiple Locations, Japan Collapse << |
| NCT00688376 | Attention Impairment | Phase 3 | Completed | - | - |
| NCT00866060 | Moderate to Severe Alzheimer's... more >> Disease Collapse << | Phase 4 | Unknown | June 2013 | United Kingdom ... more >> Institute of Psychiatry Recruiting London, United Kingdom, SE5 8AF Contact: Robert J Howard, MD 020 7848 0545 r.howard@iop.kcl.ac.uk Principal Investigator: Robert J Howard, MD Collapse << |
| NCT00934375 | - | - | Completed | - | - |
| NCT00934375 | Mild Cognitive Impairment | Phase 4 | Completed | - | - |
| NCT01278407 | Dementia With Lewy Bodies (DLB... more >>) Collapse << | Phase 3 | Completed | - | - |
| NCT00478205 | Alzheimer's Disease | Phase 3 | Completed | - | United States, North Carolina ... more >> MedTrials, Inc. Hickory, North Carolina, United States, 28601 Collapse << |
| NCT01278407 | - | - | Completed | - | - |
| NCT00675025 | Down Syndrome | Phase 2 | Terminated(Sufficient evidence... more >> of efficacy not met. Discontinuation not based on any safety concerns.) Collapse << | - | - |
| NCT01251718 | - | - | Completed | - | - |
| NCT00478205 | - | - | Completed | - | - |
| NCT00959881 | Healthy Subjects | Phase 1 | Completed | - | United States, Kansas ... more >> Pfizer Investigational Site Overland Park, Kansas, United States, 66211 Collapse << |
| NCT03740178 | Alzheimer's Disease ... more >> Mild Cognitive Impairment Collapse << | Phase 1 | Not yet recruiting | June 26, 2019 | - |
| NCT00047697 | Autistic Disorder | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Western Psychiatric Institute & Clinic Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00800553 | Sleep Deprivation | Phase 4 | Completed | - | Singapore ... more >> Cognitive Neuroscience Laboratory, Duke-NUS Graduate Medical School Singapore, Singapore, 169611 Collapse << |
| NCT01584076 | Amblyopia | Phase 1 | Recruiting | December 2020 | United States, Massachusetts ... more >> Boston Children's Hospital Recruiting Boston, Massachusetts, United States, 02115 Contact: Sarah Whitecross, OC(C) 781-216-1463 sarah.whitecross@childrens.harvard.edu Contact: Carolyn Wu, MD 617-355-5685 carolyn.wu@childrens.harvard.edu Principal Investigator: Carolyn Wu, MD Principal Investigator: David Hunter, MD, PhD Sub-Investigator: Bharti Gangwani, MD Boston Children's Hospital at Waltham Recruiting Waltham, Massachusetts, United States, 02453 Contact: Sarah Whitecross, OC(C) 781-216-1463 sarah.whitecross@childrens.harvard.edu Contact: Carolyn Wu, MD 617-355-8761 carolyn.wu@childrens.harvard.edu Principal Investigator: Carolyn Wu, MD Principal Investigator: David Hunter, MD, PhD Sub-Investigator: Bharti Gangwani, MD Boston Children's Physicians South Recruiting Weymouth, Massachusetts, United States, 02190 Contact: Sarah Whitecross, OC(C) 781-216-1463 sarah.whitecross@childrens.harvard.edu Contact: Carolyn Wu, MD 617-355-8761 carolyn.wu@childrens.harvard.edu Principal Investigator: Carolyn Wu, MD Principal Investigator: David Hunter, MD, PhD Sub-Investigator: Bharti Gangwani, MD Collapse << |
| NCT00408525 | Alzheimer's Disease | Phase 1 | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Collapse << |
| NCT01466270 | - | - | Completed | - | - |
| NCT01120626 | Fragile X Syndrome | Phase 2 | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
| NCT02158910 | - | - | Completed | - | Korea, Republic of ... more >> Busan, Korea, Republic of Chungcheongbuk-do, Korea, Republic of Chungcheongnam-do, Korea, Republic of Daegu, Korea, Republic of Gangwon-do, Korea, Republic of Gwangju, Korea, Republic of Gyeonggji-do, Korea, Republic of Gyeongsangbuk-do, Korea, Republic of Gyeongsangnam-do, Korea, Republic of Jeju-do, Korea, Republic of Jeollabuk-do, Korea, Republic of Jeollanam-do, Korea, Republic of Seoul, Korea, Republic of Collapse << |
| NCT01063556 | End-Stage Renal Disease | Phase 4 | Completed | - | Japan ... more >> Moriya, Ibaraki, Japan Collapse << |
| NCT01120626 | - | - | Completed | - | - |
| NCT00467389 | Cocaine Abuse and Dependence | Phase 2 | Completed | - | United States, Missouri ... more >> VA Medical Center Kansas City, Missouri, United States, 64128 Collapse << |
| NCT01466270 | Anxiety Disorder ... more >> Breast Cancer Cognition Disorders Depression Fatigue Sleep Disorders Collapse << | Phase 2 | Completed | - | - |
| NCT01845636 | Mild Cognitive Impairment | Phase 4 | Completed | - | United States, New York ... more >> New York State Psychiatric Institute New York, New York, United States, 10032 Collapse << |
| NCT00467389 | - | - | Completed | - | - |
| NCT00369785 | Brain Tumors ... more >>Metastatic Disease Collapse << | Phase 3 | Completed | - | United States, Kansas ... more >> Associates in Womens Health, PA - North Review Wichita, Kansas, United States, 67208 Cancer Center of Kansas, PA - Medical Arts Tower Wichita, Kansas, United States, 67208 Cancer Center of Kansas, PA - Wichita Wichita, Kansas, United States, 67214 CCOP - Wichita Wichita, Kansas, United States, 67214 Via Christi Cancer Center at Via Christi Regional Medical Center Wichita, Kansas, United States, 67214 United States, Maine Central Maine Comprehensive Cancer Center at Central Maine Medical Center Lewiston, Maine, United States, 04240 United States, New Hampshire New Hampshire Oncology - Hematology, PA - Hooksett Hooksett, New Hampshire, United States, 03106 Lakes Region General Hospital Laconia, New Hampshire, United States, 03246 United States, New York Don Monti Comprehensive Cancer Center at North Shore University Hospital Manhasset, New York, United States, 11030 United States, North Dakota CCOP - MeritCare Hospital Fargo, North Dakota, United States, 58122 Trinity CancerCare Center Minot, North Dakota, United States, 58701 United States, Ohio Summa Center for Cancer Care at Akron City Hospital Akron, Ohio, United States, 44309-2090 MetroHealth Cancer Care Center at MetroHealth Medical Center Cleveland, Ohio, United States, 44109 United States Air Force Medical Center - Wright-Patterson Wright-Patterson Air Force Base, Ohio, United States, 45433-5529 United States, Tennessee Thompson Cancer Survival Center Knoxville, Tennessee, United States, 37916 United States, Wisconsin Gundersen Lutheran Center for Cancer and Blood La Crosse, Wisconsin, United States, 54601 Collapse << |
| NCT01023425 | Alzheimer's Disease ... more >> Dementia Collapse << | Not Applicable | Completed | - | Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of, 135-710 Collapse << |
| NCT00843115 | - | - | Terminated(See Detailed Descri... more >>ption.) Collapse << | - | - |
| NCT00369785 | - | - | Completed | - | - |
| NCT00934531 | Falls Gait ... more >> Balance Mild Cognitive Impairment (MCI) Collapse << | Not Applicable | Active, not recruiting | June 2017 | Canada, Ontario ... more >> St. Joseph's Health Care London, Parkwood Hospital London, Ontario, Canada, N6C 5J1 Collapse << |
| NCT01845636 | - | - | Completed | - | - |
| NCT00352664 | Advanced Cancer | Phase 3 | Terminated(Low patient accrual... more >>) Collapse << | - | United States, Texas ... more >> U.T. M.D. Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00352664 | - | - | Terminated(Low patient accrual... more >>) Collapse << | - | - |
| NCT03349320 | - | - | Completed | - | - |
| NCT01146509 | Migraine Headache | Phase 2 | Completed | - | United States, Illinois ... more >> Diamond Headache Clinical Chicago, Illinois, United States, 60614 United States, Missouri Clinvest/Headache Care Center Springfield, Missouri, United States, 65804 United States, New York Elkind Headache Center Mount Vernon, New York, United States, 10550 United States, Pennsylvania The Clinical Trial Center, LLC Jenkintown, Pennsylvania, United States, 19046 Collapse << |
| NCT00843115 | - | - | Terminated(See Detailed Descri... more >>ption.) Collapse << | - | - |
| NCT01822951 | Alzheimer Disease | Phase 4 | Withdrawn | December 2016 | Austria ... more >> AKh Allgemeines Krankenhaus der Stadt Linz GmbH Linz, Austria, 4021 Collapse << |
| NCT00594633 | Brain Tumor B... more >>rain Cancer Cns Cancer Cognitive Dysfunction Collapse << | Phase 1 | Completed | - | United States, New York ... more >> Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Collapse << |
| NCT00220584 | Fragile X Syndrome | Phase 1 | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
| NCT01023867 | Alzheimer's Disease ... more >> Dementia Collapse << | Not Applicable | Completed | - | Korea, Republic of ... more >> Samsung Medical Center Seoul City, Korea, Republic of, 135-710 Collapse << |
| NCT01738295 | Healthy | Not Applicable | Completed | - | Canada, Quebec ... more >> School of optometry / Université de Montréal Montréal, Quebec, Canada, H3T 1P1 Collapse << |
| NCT03109314 | Amblyopia | Phase 4 | Recruiting | December 2018 | United States, California ... more >> University of California, Berkeley Recruiting Berkeley, California, United States, 94720 Contact: Dennis M Levi, OD, PhD 510-643-8685 dlevi@berkeley.edu Contact: Roger W Li, OD, PhD 510-643-8685 oroger@berkeley.edu Sub-Investigator: Susana T Chung, OD, PhD Sub-Investigator: Michael A Silver, PhD Collapse << |
| NCT00477659 | Alzheimer's Disease | Phase 4 | Completed | - | United States, Wisconsin ... more >> Pfizer Investigational Site Milwaukee, Wisconsin, United States, 53226 Collapse << |
| NCT00457769 | Stroke Vascul... more >>ar Dementia Memory Deficits Collapse << | Phase 1 | Active, not recruiting | December 2019 | United States, New Jersey ... more >> Kessler Foundation West Orange, New Jersey, United States, 08902 Collapse << |
| NCT01042314 | Alzheimer Disease | Phase 1 | Completed | - | United States, Maryland ... more >> Parexel International - Baltimore Epcu Baltimore, Maryland, United States, 21225 Collapse << |
| NCT02012595 | - | - | Completed | - | Denmark ... more >> Dept. of Nuclear Medicine & PET Center, Aarhus University Hospital Aarhus, Denmark, 8000 Collapse << |
| NCT01442766 | Acute Stroke | Phase 1 Phase 2 | Unknown | May 2014 | United Kingdom ... more >> Charing Cross Hospital, Imperial College Academic Health Science Centre Not yet recruiting London, United Kingdom, W6 8RF Contact: Paul Bentley, MA MRCP PhD 02033111184 p.bentley@imperial.ac.uk Collapse << |
| NCT02711683 | - | - | Recruiting | March 2018 | China, Shaanxi ... more >> First Affiliated Hospital of Xi'an Jiaotong University Recruiting Xi'an, Shaanxi, China, 710061 Contact: Jin Wang 0086-13572208524 drwangjin@163.com Collapse << |
| NCT01490567 | Impaired Cognition ... more >> Schizophrenia Collapse << | Phase 4 | Unknown | June 2012 | China, Hunan ... more >> the Second Xiangya Hospital of Central South University Recruiting Changsha, Hunan, China, 410011 Contact: Xiaofeng Guo, Doctor 86-731-85554052 gxfd@sina.com.cn Collapse << |
| NCT00754013 | Down Syndrome ... more >> Cognitive Dysfunction Collapse << | Phase 3 | Terminated(Sufficient evidence... more >> of efficacy not met.) Collapse << | - | United States, Texas ... more >> Road Runner Research San Antonio, Texas, United States, 78258 United States, Virginia NeuroScience, Inc. Herndon, Virginia, United States, 20170 Collapse << |
| NCT00754013 | - | - | Terminated(Sufficient evidence... more >> of efficacy not met.) Collapse << | - | - |
| NCT01191918 | Bipolar Disorder ... more >> Mania Collapse << | Phase 4 | Completed | - | - |
| NCT02927522 | Osteoarthritis ... more >> Femoral Head Necrosis Rheumatoid Arthritis Collapse << | Phase 3 | Not yet recruiting | October 2019 | - |
| NCT01504516 | Healthy | Phase 1 | Completed | - | India ... more >> Bioserve Clinical Research Private Limited Hyderabad, Andhra Pradesh, India, 500 037 Collapse << |
| NCT02448784 | - | - | Completed | - | Japan ... more >> Tokyo, Japan Collapse << |
| NCT01743976 | Neuropathic Pain | Phase 4 | Active, not recruiting | December 2018 | United States, North Carolina ... more >> Wake Forest Baptist Medical Center Winston-Salem, North Carolina, United States, 27157 Wake Forest Baptist Health Winston-Salem, North Carolina, United States, 27295 Collapse << |
| NCT01504503 | Healthy | Phase 1 | Completed | - | India ... more >> Bioserve Clinical Research Private Limited Hyderabad, Andhra Pradesh, India, 500 037 Collapse << |
| NCT02968719 | Alzheimer Disease | Phase 1 | Completed | - | United States, Arizona ... more >> Celerion Phoenix, Arizona, United States, 85283 Collapse << |
| NCT03299257 | OSA Sleepines... more >>s Collapse << | Phase 4 | Not yet recruiting | March 2, 2019 | Brazil ... more >> Instituto do Sono Active, not recruiting Sao Paulo, Brazil, 04024-002 Collapse << |
| NCT02064920 | Alzheimer's Disease | Phase 2 | Completed | - | - |
| NCT02064920 | - | - | Completed | - | - |
| NCT01297036 | Alzheimer Disease | Phase 1 | Completed | - | Korea, Republic of ... more >> Dept. of Clinical Pharmacology & Toxicology, Anam Hospital, Korea University College of Medicine Seoul, Korea, Republic of, 136-705 Collapse << |
| NCT00912457 | Obstructive Sleep Apnea | Phase 4 | Unknown | December 2009 | Brazil ... more >> Instituto do Sono / Associacao Fundo de Incentivo a Psicofarmacologia Recruiting Sao Paulo, Brazil, 04020-060 Contact: Lucia Sukys-Claudino, MD (55-48)-9129-7576 lucia@neuromeddiagnosticos.com.br Contact: Walter Moraes, MD, PhD (55-11)-5573-9238 walter.moraes@afip.com.br Principal Investigator: Sergio Tufik, MD, PhD Sub-Investigator: Dalva Poyares, MD, PhD Collapse << |
| NCT02822573 | Cognitive Dysfunction ... more >> Memory Impairment Collapse << | Phase 3 | Recruiting | October 12, 2020 | United States, North Carolina ... more >> Wake Forest School of Medicine Recruiting Winston-Salem, North Carolina, United States, 27157 Contact: Tammy Vogler, RN 336-713-6907 tvogler@wakehealth.edu Collapse << |
| NCT00465283 | Schizophrenia ... more >> Schizoaffective Disorder Schizophreniform Disorder Collapse << | Phase 4 | Unknown | January 2010 | Israel ... more >> Beer Yaakov MHC Recruiting Beer Yaacov, Israel, 70350 Contact: Tali Nachshoni, M.D. 972-8-9258372 bynachshoni@beer-ness.health.gov.il Principal Investigator: Tali Nachshoni, MD Collapse << |
| NCT02097056 | - | - | Completed | - | - |
| NCT01521117 | Parkinson's Disease | Phase 4 | Unknown | July 2012 | United States, Oregon ... more >> Parkinson's Center of Oregon - Oregon Health and Science University Recruiting Portland, Oregon, United States, 97239 Contact: Seth Kareus, MD kareus@ohsu.edu Collapse << |
| NCT02331771 | Memory Impairment | Not Applicable | Terminated(Lack of sufficient ... more >>enrollment) Collapse << | - | United States, Colorado ... more >> Porter Adventist Hospital Denver, Colorado, United States, 80210 Collapse << |
| NCT01633593 | Elderly Delir... more >>ium of Unknown (Axis III) Etiology Intensive Care (ICU) Myopathy Collapse << | Phase 4 | Terminated(Difficulty in recru... more >>iting subjects for the trial.) Collapse << | - | Brazil ... more >> FAMEMA Marilia, Sao Paulo, Brazil, 1750000 Collapse << |
| NCT02097056 | Alzheimer's Disease | Phase 4 | Completed | - | Korea, Republic of ... more >> Chungju, Chungcheongbuk-do, Korea, Republic of Ansan, Gyeonggi-do, Korea, Republic of Buchoen, Gyeonggi-do, Korea, Republic of Seongnam, Gyeonggi-do, Korea, Republic of Jinju, Gyeongsangnam-do, Korea, Republic of Iksan, Jeollabuk-do, Korea, Republic of Hwasun, Jeollanam-do, Korea, Republic of Busan, Korea, Republic of Daegu, Korea, Republic of Daejeon, Korea, Republic of Incheon, Korea, Republic of Jeju, Korea, Republic of Seoul, Korea, Republic of Collapse << |
| NCT02305836 | Cognitive Impairment | Phase 2 | Recruiting | December 2019 | China ... more >> Guang'an Men Hospotal Affiliated to China Academy of Chinese Medical Sciences Recruiting Beijing, China, 100053 Contact: Weina Peng 86-18610935028 wnpeng@hotmail.com Collapse << |
| NCT02415062 | Parkinson's Disease | Phase 2 | Unknown | December 2017 | Korea, Republic of ... more >> Inje university, busan paik hospital Recruiting Busan, Korea, Republic of Contact: Sang-jin kim, professor 82-10-9525-6207 jsk120@hanmail.net Collapse << |
| NCT01260922 | Healthy | Phase 1 | Completed | - | United States, Minnesota ... more >> PRACS Institute, Ltd. East Grand Forks, Minnesota, United States, 56721 Collapse << |
| NCT03073876 | Alzheimer Disease | Phase 4 | Active, not recruiting | July 31, 2019 | United States, New York ... more >> Winthrop-University Hospital Mineola, New York, United States, 11501 Collapse << |
| NCT01260948 | - | - | Completed | - | - |
| NCT01260922 | - | - | Completed | - | - |
| NCT03698695 | Cognitive Impairment ... more >> Alzheimer Disease Collapse << | Phase 1 | Recruiting | July 31, 2019 | France ... more >> CHU Bordeaux Not yet recruiting Bordeaux, France Contact: Pierre-Olivier Girodet, Prof. CHU Clermont Ferrand Recruiting Clermont-Ferrand, France Contact: Gisèle Pickering, Prof. CHU Grenoble Not yet recruiting Grenoble, France Contact: Jean-Luc Cracowski, Prof. CHU Lille Recruiting Lille, France Contact: Dominique Deplanque, Prof. CHU Marseille Recruiting Marseille, France Contact: Olivier Blin, Prof. Biotrial Recruiting Rennes, France Contact: Hakim Charfi, Dr. CHU Toulouse Not yet recruiting Toulouse, France Contact: Claire Thalamas, Dr. Collapse << |
| NCT01877538 | - | - | Completed | - | - |
| NCT01260948 | Healthy | Phase 1 | Completed | - | United States, Minnesota ... more >> PRACS Institute, Ltd. East Grand Forks, Minnesota, United States, 56721 Collapse << |
| NCT01014858 | Parkinson's Disease | Phase 3 | Terminated(Due to low recruitm... more >>ent) Collapse << | - | United Kingdom ... more >> Newcastle Newcastle Upon Tyne, Tyne and Wear, United Kingdom, NE4 5PL Royal United Hospital (RUH) Bath NHS Bath, United Kingdom, BA1 3NG Sandwell and West Birmingham NHS Foundation Trust Birmingham, United Kingdom, B18 7QH Steps and Pines, Southmead Hospital Bristol, United Kingdom, BS10 5NB Pennine Acute Hospitals NHS Trust Bury, United Kingdom, BL9 7TD Cambridge Centre for Brain Repair Cambridge, United Kingdom, CB2 0PY Dr Lakmali Sugathapala Derby, United Kingdom, DE22 3NE Royal Bournemouth & Christchurch Hospitals NHS Foundation Trust Dorset, United Kingdom, BH23 2JX NHS Greater Glasgow and Clyde Glasgow, United Kingdom, G51 4TF Dr Pippa Metcalf Gloucester, United Kingdom, Gloucester Llandudno Hospital, Betsi Cadwaladr University Health Board & School of Medical Sciences Llandudno, United Kingdom, LL30 1LB King's College Hospital NHS Foundtion Trust London, United Kingdom, SE59RS Manchester Mental Health & Social Care NHS Trust Manchester, United Kingdom, M8 5RB Milton Keynes Milton Keynes, United Kingdom, MK6 5LD Royal Gwent Hospital Newport, United Kingdom, NP20 2UB North Tyneside General Hospital Northumberland, United Kingdom, NE29 8NH Norfolk and Norwich University Hospitals NHS Foundation Trust Norwich, United Kingdom, NR4 7UY Oxford University Hospitals NHS Foundation Trust Oxford, United Kingdom, OX3 9DU Plymouth Hospitals NHS Trust Plymouth, United Kingdom, PL6 8DH Poole Hospital NHS Trust Poole, United Kingdom, BH15 2JB Southampton General Hospital Southampton, United Kingdom, SO16 6YD Dr Dhakam Surrey, United Kingdom, KT16 0PZ Collapse << |
| NCT01951118 | Alzheimer Disease ... more >> Mild Cognitive Impairment Delirium, Dementia, Amnestic, Cognitive Disorders Collapse << | Phase 4 | Active, not recruiting | May 2019 | United States, New York ... more >> New York State Psychiatric Institute New York, New York, United States, 10032 Collapse << |
| NCT01923259 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Algorithme Pharma Inc. Mount Royal, Quebec, Canada, H3P 3P1 Collapse << |
| NCT01923558 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Algorithme Pharma Inc. Mount Royal, Quebec, Canada, H3P 3P1 Collapse << |
| NCT01877538 | - | - | Completed | - | Denmark ... more >> Dep. of Nuclear Medicine and PET centre, Aarhus University Hospital Aarhus, Denmark, 8000 Collapse << |
| NCT02660983 | Dementia Associated With Cereb... more >>rovascular Disease Collapse << | Phase 4 | Active, not recruiting | January 1, 2019 | Korea, Republic of ... more >> Seo-Gu, Busan, Korea, Republic of Buk-Gu, Daegu, Korea, Republic of Jung-Gu, Daegu, Korea, Republic of Nam-Gu, Daegu, Korea, Republic of Chuncheon-Si, Gangwon-do, Korea, Republic of Donggu, Gwangju, Korea, Republic of Anyang, Gyeonggi-do, Korea, Republic of Bucheon-Si, Gyeonggi-do, Korea, Republic of Goyang-Si, Gyeonggi-do, Korea, Republic of Seongnam-Si, Gyeonggi-do, Korea, Republic of Suwon-City, Gyeonggi-do, Korea, Republic of Wonmi-Gu, Gyeonggi-do, Korea, Republic of Changwon-Si, Gyeongsangnam-do, Korea, Republic of Yangsan-Si, Gyeongsangnam-do, Korea, Republic of Jung-Gu, Incheon, Korea, Republic of Namdong-Gu, Incheon, Korea, Republic of Dongjak-Gu, Seoul, Korea, Republic of Gangdong-Gu, Seoul, Korea, Republic of Gangnam-Gu., Seoul, Korea, Republic of Gwangjin-Gu, Seoul, Korea, Republic of Jongno-Gu, Seoul, Korea, Republic of Jungnang-Gu, Seoul, Korea, Republic of Seocho-Gu, Seoul, Korea, Republic of Seodaemun-Gu, Seoul, Korea, Republic of Seongbuk-Gu, Seoul, Korea, Republic of Seongdong-Gu, Seoul, Korea, Republic of Songpa-Gu, Seoul, Korea, Republic of Yangcheon-Ku, Seoul, Korea, Republic of Yeongdeungpo-Gu, Seoul, Korea, Republic of Collapse << |
| NCT01439230 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Montreal, Quebec, Canada, H3X 2H9 Collapse << |
| NCT02550665 | Alzheimer's Disease | Phase 3 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of, 05505 Collapse << |
| NCT03259958 | Alzheimer's Disease | Phase 1 | Completed | - | United States, Arizona ... more >> Celerion Inc. Phoenix, Arizona, United States, 85283 Collapse << |
| NCT03599726 | Parkinson Disease | Early Phase 1 | Recruiting | January 1, 2019 | United States, Oregon ... more >> Oregon Health & Science University Recruiting Portland, Oregon, United States, 97239 Contact: Makena Strand 503-418-2602 strandm@ohsu.edu Principal Investigator: Martina Mancini, PhD Collapse << |
| NCT02255799 | Traumatic Brain Injury ... more >> Memory Deficits Collapse << | Phase 3 | Recruiting | September 2018 | United States, Indiana ... more >> Indiana University Recruiting Indianapolis, Indiana, United States, 46202 Contact: Becky Runkel, MHA 317-329-2217 becky.runkel@rhin.com Principal Investigator: Flora Hammond, MD United States, Massachusetts Spaulding Rehabilitation Hospital Recruiting Charlestown, Massachusetts, United States, 02129 Contact: Joseph Giacino, PhD 617-952-5232 jgiacino@partners.org Contact: Ross Zafonte, DO 617-952-5227 rzafonte@partners.org Principal Investigator: Joseph Giacino, PhD Sub-Investigator: Ross Zafonte, DO United States, Pennsylvania Moss Rehabilitation Research Institute Recruiting Elkins Park, Pennsylvania, United States, 19027 Contact: Tessa Hart, PhD 215-663-6153 thart@einstein.edu Contact: John Whyte, MD, PhD 215-663-6872 jwhyte@einstein.edu Principal Investigator: Tessa Hart, PhD Sub-Investigator: John Whyte, MD, PhD United States, Texas TIRR Memorial Hermann Recruiting Houston, Texas, United States, 77030 Contact: Jay Bogaards, MA 713-797-7102 Jay.Bogaards@memorialhermann.org Contact: Angelle Sander, PhD 713-797-7161 Angelle.Sander@memorialhermann.org Principal Investigator: Angelle Sander, PhD Sub-Investigator: Mark Sherer, PhD Collapse << |
| NCT03438604 | Alzheimer's Disease | Phase 1 | Completed | - | United States, Arizona ... more >> Celerion Phoenix, Arizona, United States, 85283 Collapse << |
| NCT03397862 | Skin Irritation ... more >> Sensitization Collapse << | Phase 1 | Completed | - | United States, Arizona ... more >> Celerion Inc. Phoenix, Arizona, United States, 85283 United States, Nebraska Celerion Inc. Lincoln, Nebraska, United States, 68502 Collapse << |
| NCT02787746 | Alzheimer's Disease | Phase 4 | Active, not recruiting | December 2018 | China, Beijing ... more >> Beijing Friendship Hospital, Capital Medical University Beijing, Beijing, China Collapse << |
| NCT02222727 | Aneurysmal Subarachnoid Hemorr... more >>hage Delayed Neurological Deficit Delayed Cerebral Ischemia Vasospasm Collapse << | Phase 2 | Terminated(CT scanner software... more >> incompatible) Collapse << | - | United Kingdom ... more >> St George's University of London London, United Kingdom, SW17 0RE Collapse << |
| NCT03432195 | Alzheimer's Disease | Phase 1 | Completed | - | United States, Arizona ... more >> Celerion Tempe, Arizona, United States, 85283 Collapse << |
| NCT01439243 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Montreal, Quebec, Canada, H3X 2H9 Collapse << |
| NCT02839642 | Progressive Supranuclear Palsy... more >> (PSP) Collapse << | Phase 3 | Recruiting | November 2019 | France ... more >> Service de Neurologie et Pathologie du Mouvement Hôpital de La Timone Recruiting Marseille Cedex 5, France, 13385 Contact: Alexandre EUSEBIO, Dr 04.91.38.43.33 ext +33 alexandre.eusebio@ap-hm.fr Collapse << |
| NCT02626572 | Alzheimer's Disease | Phase 2 | Completed | - | - |
| NCT03025334 | Parkinson Disease ... more >> Mild Cognitive Impairment Collapse << | Not Applicable | Recruiting | December 2020 | Canada, Manitoba ... more >> University of Manitoba Recruiting Winnipeg, Manitoba, Canada, R3E 0J9 Contact: Ji Hyun Ko, PhD 204-318-2566 ji.ko@umanitoba.ca Collapse << |
| NCT01213355 | Healthy | Phase 1 | Completed | - | France ... more >> Pfizer Investigational Site Rennes, France, 35000 Collapse << |
| NCT01253434 | Japanese Healthy Male Adult Vo... more >>lunteers Collapse << | Phase 1 | Completed | - | Japan ... more >> Kagoshima, Japan Collapse << |
| NCT02570581 | Healthy | Phase 1 | Completed | - | France ... more >> Center for Clinical Research - Archet 1 Hospital Nice Hospital Nice, France, 06200 Collapse << |
| NCT01554475 | - | - | Completed | - | Norway ... more >> Kløveråsen Bodø, Norway, N-8076 Collapse << |
| NCT01401582 | - | - | Active, not recruiting | - | - |
| NCT02549196 | Dementia of Alzheimer's Type | Phase 2 | Completed | - | United States, Florida ... more >> Quantum Laboratories Deerfield Beach, Florida, United States, 33064 Collapse << |
| NCT02462291 | Alzheimer Disease ... more >> Behavioral Disorders Cognitive Impairment Collapse << | Not Applicable | Completed | - | Italy ... more >> Mons. Mazzali Foundation Mantua Italy, Mantua, Italy, 46100 Collapse << |
| NCT01401582 | Dementia | Not Applicable | Active, not recruiting | March 2018 | Germany ... more >> Institute for Community Medicine Greifswald, Mecklenburg- Western Pommerania, Germany, 17489 Collapse << |
| NCT02860338 | - | - | Completed | - | - |
| NCT00291421 | - | - | Completed | - | - |
| NCT00548145 | Alzheimer Disease ... more >> Hypercholesterolemia Collapse << | Not Applicable | Terminated | - | Japan ... more >> Osaka University Hospital Suita, Osaka, Japan, 565-0871 Collapse << |
| NCT01852110 | Alzheimer's Disease | Phase 2 | Terminated(Stage 1 interim ana... more >>lysis of efficacy met the criteria for early trial termination (futility). The trial was terminated at Stage 1; did not proceed to Stage 2.) Collapse << | - | - |
| NCT02696512 | Brain Injury | Phase 1 Phase 2 | Unknown | April 2017 | United States, New Jersey ... more >> International Brain Research Foundation Recruiting Edison, New Jersey, United States, 08837 Contact: Philip Defina, PhD 732-494-7600 pdefina@ibrfinc.org Principal Investigator: Philip Defina, PhD Collapse << |
| NCT01852110 | - | - | Terminated(Stage 1 interim ana... more >>lysis of efficacy met the criteria for early trial termination (futility). The trial was terminated at Stage 1; did not proceed to Stage 2.) Collapse << | - | - |
| NCT02374567 | Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse << | Phase 3 | Terminated | - | Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse << |
| NCT00548145 | - | - | Terminated | - | - |
| NCT02462291 | - | - | Completed | - | - |
| NCT01249196 | Alzheimer's Disease | Phase 3 | Completed | - | Korea, Republic of ... more >> SKChemicals invetigational site Seoul, Korea, Republic of Collapse << |
| NCT02623764 | - | - | Active, not recruiting | November 2019 | - |
| NCT01696591 | - | - | Unknown | September 2013 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Seoul, Korea, Republic of, 135-710 Contact: Duk L. Na, MD, PhD +82-2-3410-3594 dukna@naver.com Collapse << |
| NCT03565809 | - | - | Enrolling by invitation | December 2018 | France ... more >> University Hospital Toulouse, France, 31000 Collapse << |
| NCT00880412 | Alzheimer's Disease | Phase 2 | Completed | - | France ... more >> Hôpital Privé Les Magnolias Ballainvilliers, France, 91160 Cabinet Médical Bergerac, France, 24100 Fleyriat Hospital Bourg en Bresse, France, 01012 Cabinet Médical Dijon, France, 21000 Charles Foix Hospital Ivry sur Seine, France, 94026 Cabinet Médical La Seyne sur Mer, France, 83500 Roger Salengro Hospital Lille, France, 59037 Dupuytren Hospital Limoges, France, 87042 Clinique Léopold Bellan Magnanville, France, 78200 Cabinet Médical Montpellier, France, 34070 Cabinet Médical 2 Montpellier, France, 34080 CHU Nantes Hôpital Laennec Nantes, France, 44093 Cabinet Médical 2 Nice, France, 06000 Cabinet Médical Nice, France, 06000 CHU Cochin Broca Paris, France, 75013 Cabinet Médical Rambouillet, France, 78120 CHU Rennes Rennes, France, 35033 Cabinet Médical Rodez, France, 12000 Cabinet Médical Rueil Malmaison, France, 92500 Cabinet Médical Saint Brieuc, France, 22000 Cabinet Médical Toulon, France, 83000 Purpan-Casselardit Hospital - University of Toulouse Toulouse, France, 31059 Collapse << |
| NCT00348140 | Alzheimer's Disease | Phase 3 | Completed | - | - |
| NCT00702780 | Alzheimer's Disease | Not Applicable | Completed | - | Korea, Republic of ... more >> Kangwon National University Hospital Chuncheon, Korea, Republic of Seoul National University Bundang Hospital Seongnam, Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Konkuk University Hospital Seoul, Korea, Republic of Collapse << |
| NCT02670161 | Brain Tumors ... more >>Epilepsy Migraine Mild Cognitive Impairment Concussion Multiple Sclerosis Neuropathy Parkinson's Restless Legs Syndrome Stroke Collapse << | Phase 4 | Enrolling by invitation | April 2020 | - |
| NCT00702780 | - | - | Completed | - | - |
| NCT00348140 | - | - | Completed | - | - |
| NCT00105105 | Alzheimer's Disease | Phase 2 | Terminated | - | United States, Arizona ... more >> Pivotal Research Center Mesa, Arizona, United States, 85210 Pivotal Research Center Peoria, Arizona, United States, 85381 United States, California ATP Clinical Trials Fountain Valley, California, United States, 92708 UCI Irvine Medical Center Orange, California, United States, 92868 California Neuroscience Research Medical Group, Inc. Sherman Oaks, California, United States, 91403 AVI Clinical Research Torrance, California, United States, 90505 United States, Florida Baumel-Eisner Neuromed Inst Boca Raton, Florida, United States, 33486 Baumel-Eisner Neuromed Inst Ft. Lauderdale, Florida, United States, 33321 Clinical Physiology Associates Ft. Myers, Florida, United States, 33916 Baumel-Eisner Neuromed Inst Miami Beach, Florida, United States, 33154 Stedman Clinical Trials Tampa, Florida, United States, 33613 Johnnie B. Byrd, Sr. Alzheimer's Center & Research Inst Tampa, Florida, United States, 33647 United States, New Jersey Memory Enhancement Center Long Branch, New Jersey, United States, 07740 United States, New York Eastside Medical Research New York, New York, United States, 10021 United States, Ohio Neuro Center of Ohio Toledo, Ohio, United States, 43623 United States, Oklahoma Pahl Pharmaceutical Research, LLC Oklahoma City, Oklahoma, United States, 73118 Clinical Pharmaceutical Trials, Inc. Tulsa, Oklahoma, United States, 74104 United States, Pennsylvania Clinical Trials Research Services Pittsburgh, Pennsylvania, United States, 15206 United States, Texas Grayline Clinical Drug Trials Wichita Falls, Texas, United States, 76309 United States, Virginia International Clinical Research Associates Richmond, Virginia, United States, 23229 International Clinical Research Associates Virginia Beach, Virginia, United States, 23452 Collapse << |
| NCT00951834 | Alzheimer's Disease | Phase 2 Phase 3 | Completed | - | Germany ... more >> Charite University Medicine Berlin Berlin, Germany, 10117 Charité Universitätsmedizin Berlin Klinik für Psychiatrie und Psychotherapie Berlin, Germany, 10117 Klinik für Neurologie Ulm, Germany, 89081 Collapse << |
| NCT02586909 | Alzheimer's Disease | Phase 3 | Terminated(Intepirdine did not... more >> meet its primary efficacy endpoints in lead-in study RVT-101-3001.) Collapse << | - | - |
| NCT02491268 | Mild Cognitive Impairment | Phase 2 | Recruiting | December 2020 | Japan ... more >> National Cerebral and Cardiovascular Center Recruiting Suita, Osaka, Japan, 565-8565 Contact: Masafumi Ihara, MD, PhD, FACP +81668335012 ihara@ncvc.go.jp Contact: Ryosuke Kakuta +81668335012 r_kakuta@ncvc.go.jp Principal Investigator: Kazuyuki Nagatsuka, MD, PhD Collapse << |
| NCT01450839 | Healthy | Phase 1 | Completed | - | Japan ... more >> Kagoshima, Japan Collapse << |
| NCT01626391 | Alzheimer's Disease | Phase 2 | Terminated(This study has been... more >> terminated for administrative reasons only.) Collapse << | - | Germany ... more >> Achim, Germany Berlin, Germany Leipzig, Germany München, Germany United Kingdom Birmingham, United Kingdom Bradford, United Kingdom Crowborough, United Kingdom Duston, United Kingdom Oxford, United Kingdom Sheffield, United Kingdom St Leonards on Sea, United Kingdom Staffordshire, United Kingdom Collapse << |
| NCT03352739 | Alzheimer Disease | Not Applicable | Recruiting | December 1, 2020 | China ... more >> Xuanwu Hospital, Capital Medical University. Recruiting Beijing, China, 100053 Contact: Peng-Hu Wei, M.D. +86-18601986863 Collapse << |
| NCT01152216 | Alzheimer's Disease | Phase 3 | Terminated | - | - |
| NCT00051909 | Alzheimer's Disease | Phase 2 | Completed | - | United States, California ... more >> Beverly Hills, California, United States Fresno, California, United States United States, Florida Boca Raton, Florida, United States Fort Lauderdale, Florida, United States Miami Beach, Florida, United States United States, Massachusetts Boston, Massachusetts, United States United States, Oklahoma Oklahoma City, Oklahoma, United States Tulsa, Oklahoma, United States United States, Texas Wichita Falls, Texas, United States Collapse << |
| NCT01626391 | - | - | Terminated(This study has been... more >> terminated for administrative reasons only.) Collapse << | - | - |
| NCT01428362 | Alzheimer's Disease | Phase 2 | Completed | - | United States, California ... more >> San Francisco, California, United States, 94109 Santa Monica, California, United States, 90404 United States, Florida Sunrise, Florida, United States, 33351 United States, Kentucky Louisville, Kentucky, United States, 40217 United States, Nevada Las Vegas, Nevada, United States, 89113 United States, New Jersey Toms River, New Jersey, United States, 08755 United States, New York New Windsor, New York, United States, 12553 United States, North Carolina Durham, North Carolina, United States, 27710 Raleigh, North Carolina, United States, 27612 United States, Ohio Toledo, Ohio, United States, 43623 United States, Texas Plano, Texas, United States, 75075 Collapse << |
| NCT01872598 | Alzheimer Disease | Phase 3 | Active, not recruiting | October 2019 | Spain ... more >> Hospital Universitario Ramón y Cajal Madrid, Spain, 28034 Collapse << |
| NCT02185053 | Alzheimer's Disease | Phase 2 | Completed | - | United States, Florida ... more >> CPC1 West Palm Beach, Florida, United States Collapse << |
| NCT01677754 | Alzheimer's Disease | Phase 2 | Completed | - | - |
| NCT00018278 | Alzheimer Disease | Phase 4 | Completed | - | United States, California ... more >> Department of Veterans Affairs San Diego, California, United States, 92161 Collapse << |
| NCT01944436 | - | - | Completed | - | Canada, Ontario ... more >> Sunnybrook Health Sciences Centre Toronto, Ontario, Canada, M4N3M5 Collapse << |
| NCT02918266 | Healthy Volunteers | Phase 1 | Terminated(Terminated prematur... more >>ely due to indication change.) Collapse << | - | United States, California ... more >> Glendale, California, United States Collapse << |
| NCT00004807 | Rett Syndrome | Not Applicable | Completed | - | - |
| NCT02337907 | Alzheimer Disease | Phase 2 | Completed | - | - |
| NCT00519298 | Healthy Adult | Phase 1 | Completed | - | France ... more >> Rouffach, France, 68250 Collapse << |
| NCT00234637 | Alzheimer's Disease | Phase 4 | Completed | - | France ... more >> Département de Gérontologie Clinique Limoges, Cedex, France, 87042 Collapse << |
| NCT01529619 | Alzheimer's Disease | Phase 4 | Completed | - | Japan ... more >> Novartis Investigative Site Nagoya-city, Aichi, Japan, 467-8602 Novartis Investigative Site Fukuoka-city, Fukuoka, Japan, 814-0180 Novartis Investigative Site Miyoshi-city, Hiroshima, Japan, 728-0013 Novartis Investigative Site Ohtake, Hiroshima, Japan, 739-0696 Novartis Investigative Site Kita-gun, Kagawa, Japan, 761-0793 Novartis Investigative Site Kamakura-city, Kanagawa, Japan, 247-8533 Novartis Investigative Site Kawasaki-city, Kanagawa, Japan, 216-8511 Novartis Investigative Site Yokohama, Kanagawa, Japan, 241-0811 Novartis Investigative Site Koshi-city, Kumamoto, Japan, 861-1116 Novartis Investigative Site Kyoto-city, Kyoto, Japan, 600-8558 Novartis Investigative Site Kyoto, Japan, 606-0851 Collapse << |
| NCT02337907 | - | - | Completed | - | - |
| NCT02007291 | - | - | Completed | - | - |
| NCT03221894 | - | - | Recruiting | September 2017 | China ... more >> Dongzhimen Hospital Recruiting Beijing, China Contact: Jing Shi, M.D. 86-10-84013132 shijing87@hotmail.com Collapse << |
| NCT02007291 | - | - | Completed | - | - |
| NCT00006399 | Alzheimer Disease | Phase 2 | Completed | - | United States, Vermont ... more >> Clinical Neuroscience Research Unit, University of Vermont Burlington, Vermont, United States, 05401 Collapse << |
| NCT03184467 | Alzheimer Disease | Phase 2 | Recruiting | June 2019 | Korea, Republic of ... more >> Hanyang University Guri Hospital Recruiting Guri-si, Gyunggi-do, Korea, Republic of, 11923 Contact: Seong-Ho Koh, MD, PhD. ksh213@hanyang.ac.kr Collapse << |
| NCT01843556 | Healthy Elderly Male | Phase 1 | Completed | - | Japan ... more >> Kagoshima, Japan Collapse << |
| NCT00428090 | Alzheimer's Disease | Phase 3 | Completed | - | - |
| NCT02703636 | Mild to Moderate Alzheimer's D... more >>isease Collapse << | Phase 4 | Completed | - | Japan ... more >> Novartis Investigative Site Fukuoka-city, Fukuoka, Japan, 814-001 Novartis Investigative Site Fukuoka-city, Fukuoka, Japan, 814-0180 Novartis Investigative Site Aizuwakamatsu, Fukushima, Japan, 965-8585 Novartis Investigative Site Tsukuba-city, Ibaraki, Japan, 305-8576 Novartis Investigative Site Kita-gun, Kagawa, Japan, 761-0793 Novartis Investigative Site Sagamihara-city, Kanagawa, Japan, 252-5188 Novartis Investigative Site Kochi-city, Kochi, Japan, 780-0842 Novartis Investigative Site Kurashiki-city, Okayama, Japan, 710-0826 Novartis Investigative Site Osaka-city, Osaka, Japan, 543-8555 Novartis Investigative Site Suita-city, Osaka, Japan, 565 0871 Novartis Investigative Site Kasukabe-city, Saitama, Japan, 344-0036 Novartis Investigative Site Koshigaya-city, Saitama, Japan, 343-0032 Novartis Investigative Site Fuji-city, Shizuoka, Japan Novartis Investigative Site Bunkyo-ku, Tokyo, Japan, 113-8431 Novartis Investigative Site Hachioji-city, Tokyo, Japan, 193-0944 Novartis Investigative Site Shinjuku-ku, Tokyo, Japan, 160-0023 Novartis Investigative Site Niigata, Japan Novartis Investigative Site Okayama, Japan, 710-0813 Novartis Investigative Site Tokyo, Japan, 168-8535 Collapse << |
| NCT01028911 | Alzheimer's Disease | Phase 1 | Terminated(This study terminat... more >>ed 27Apr2010 due to slow recruitment and the need to use the existing information to determine dosing for another study.) Collapse << | - | United States, Kansas ... more >> Pfizer Investigational Site Wichita, Kansas, United States, 67207 Pfizer Investigational Site Wichita, Kansas, United States, 67211 Collapse << |
| NCT00267163 | Cognition Disorders | Phase 4 | Completed | - | United States, California ... more >> UCLA, The Semel Institute for Neuroscience and Human Behavior Los Angeles, California, United States, 90024 Collapse << |
| NCT00428090 | - | - | Completed | - | - |
| NCT03441516 | Alzheimer's Disease | Phase 4 | Enrolling by invitation | December 31, 2019 | Korea, Republic of ... more >> Dong-A University Hospital Busan, Korea, Republic of Gyeongsang National University Hospital Busan, Korea, Republic of Inje University Busan Paik Hospital Busan, Korea, Republic of Inje University Haeundae Paik Hospital Busan, Korea, Republic of Pusan National University Yangsan Hospital Busan, Korea, Republic of Samsung Changwon Hospital Busan, Korea, Republic of Collapse << |
| NCT00031018 | Memory Disorders ... more >> Alzheimer's Disease Collapse << | Phase 2 | Unknown | - | United States, Texas ... more >> University of Texas - Houston, Gerontology Center of the UTMSI Houston, Texas, United States, 77030 Collapse << |
| NCT01098383 | Autism | Phase 4 | Unknown | December 2017 | Israel ... more >> Sheba Medical Center Recruiting Tel Hashomer, Ramat Gan, Israel, 52621 Contact: Shahar Shefer, Dr +972-(0)54-4381594 DRShahar.Shefer@sheba.health.gov.il Sub-Investigator: Maaian Millikovsky, BA Collapse << |
| NCT01028911 | - | - | Terminated(This study terminat... more >>ed 27Apr2010 due to slow recruitment and the need to use the existing information to determine dosing for another study.) Collapse << | - | - |
| NCT00766363 | - | - | Completed | - | - |
| NCT00551161 | Alzheimer Disease | Phase 4 | Completed | - | United States, New York ... more >> The Litwin-Zucker Research Center Manhasset, New York, United States, 11030 Collapse << |
| NCT01527916 | Alzheimer's Disease | Phase 2 | Completed | - | - |
| NCT00551161 | - | - | Completed | - | - |
| NCT02769065 | Alzheimer Disease ... more >> Healthy Volunteers Collapse << | Phase 1 | Terminated(Terminated prematur... more >>ely as data from cohort no longer needed due to indication change.) Collapse << | - | United States, California ... more >> Glendale, California, United States Collapse << |
| NCT02187276 | - | - | Completed | - | - |
| NCT00693004 | Alzheimer's Disease | Phase 2 | Terminated | - | - |
| NCT01940952 | Alzheimer's Disease | Phase 3 | Unknown | - | Korea, Republic of ... more >> Samguns Medical Center Not yet recruiting Seoul, Korea, Republic of, 135-710 Contact: Enda Go, Clinical Research Coordinator 82-2-3410-2868 ed.ko@samsung.com Principal Investigator: Duk L. Na, MD. PhD Collapse << |
| NCT00766363 | Alzheimer's Disease ... more >> Central Nervous System Diseases Collapse << | Phase 1 | Completed | - | United States, California ... more >> Pacific Research Network, Inc. San Diego, California, United States, 92103 United States, Florida MD Clinical Hallandale Beach, Florida, United States, 33009 United States, New Jersey Comprehensive Clinical Research Berlin, New Jersey, United States, 08009 Global Medical Institutes, LLC Princeton, New Jersey, United States, 08540 Collapse << |
| NCT00443014 | Alzheimer Disease | Phase 4 | Completed | - | Norway ... more >> Arran Lulesami Centre Drag, Nordland, Norway, 8270 Collapse << |
| NCT03454646 | Alzheimer Disease ... more >> Cholinesterase Inhibitors Collapse << | Phase 4 | Not yet recruiting | September 15, 2021 | France ... more >> CHU d'Amiens Centre Mémoire Ressources Recherche Not yet recruiting Amiens, France, 80054 Contact: Agnès DEVENDEVILLE 03.22.66.82.40 devendeville.agnes@chu-amiens.fr CHU d'Angers Centre Mémoire Ressources Recherche Angers, France, 49933 CHU de Bastia Centre Mémoire Ressources Recherche Not yet recruiting Bastia, France, 20604 Contact: Georges RETTALI 04.95.59.18.32 georges.retali@ch-bastia.fr CHU de Besançon Centre Mémoire Ressources Recherche Besançon, France, 25030 CHU de Bordeaux - Service de Neurologie - Centre Mémoire Ressources Recherche - Not yet recruiting Bordeaux, France, 33076 Contact: Jean-François DARTIGUES 0557820116 jean-françois.dartigues@u-bordeaux.fr CHRU Cavale Blanche Service de Gériatrie Brest, France, 29200 Service de Neuropsychologie Hôpital Neurologique Pierre Wertheimer Not yet recruiting Bron, France, 69677 Contact: Hélène MOLLION 04.72.35.71.79 helene.mollion@chu-lyon.fr CHU Côte de Nacre Service de neurologie et CMRR Caen, France, 14033 CHU de Clermont Ferrand Centre Mémoire Ressources Recherche Clermont-Ferrand, France, 63000 Hôpital Pasteur Service de Neurologie Colmar, France, 68000 CHU de Dijon- CMRR Not yet recruiting Dijon, France, 21679 Contact: Yannick BEJOT 03.80.29.58.03 yannick.bejot@chu-dijon.fr Chu de Grenoble CMRR, Neurologie Not yet recruiting Grenoble, France, 38043 Contact: Olivier MOREAUD 04 76 76 57 90 omoreaud@chu-grenoble.fr Hôpital Roger Salengro CMRR Lille, France, 59037 CHU Limoges Service de neurologie et CMRR Not yet recruiting Limoges, France, 87000 Contact: Leslie CARTZ-PIVER 05.55.43.12.15 Lcp.coglim@gmail.com AP-HM Marseille, France CHU Montpellier Hôpital Gui de Chauliac CMRR Not yet recruiting Montpellier, France, 34295 Contact: Audrey GABOREAU DE LOUSTAL 04.67.33.60.29 a-gabelle@chu-montpellier.fr CHU de Nantes Clinique Neurologique Hôpital GR Laennec Not yet recruiting Nantes, France, 44093 Contact: Claire BOUTOLEAU 02.40.16.54.22 claire.boutoleaubretonniere@chu-nantes.fr Institut Claude Pompidou Centre Mémoire de Ressources et de Recherche Not yet recruiting Nice, France, 06100 Contact: Renaud David 04.92.03.47.70 claire.paquet@inserm.fr APHP Hôpital Broca Not yet recruiting Paris, France, 75013 Contact: Olivier HANON 01.44.08.35.03 olivier.hanon@brc.aphp.fr Hôpital Universitaire de la Pitié Salpêtrière Pavillon François Lhermitte Not yet recruiting Paris, France, 75013 Contact: Stéphane EPELBAUM 01.42.16.75.22 stephane.epelbaum@psl.aphp.fr APHP Groupe Hospitalier Saint Louis Lariboisière Fernand Widal CMRR Not yet recruiting Paris, France, 75475 Contact: Claire PAQUET 01.40.05.49.54 claire.paquet@inserm.fr CHU La Milétrie Pôle de Gériatrie Not yet recruiting Poitiers, France, 86021 Contact: Marc PACCALIN 05.49.44.44.27 m.paccalin@chu-poitiers.fr CHU Reims Hôpital Maison Blanche Court Séjour Gériatrique Not yet recruiting Reims, France, 51092 Contact: Jean-Luc NOVELLA 03.26.78.44.10 jl.novella@chu-reims.fr CHU de Rennes - Hôpital Pontchaillou / Service de Neurologie Not yet recruiting Rennes, France, 35033 Contact: Serge BELLIARD 02.99.87.30.26 serge.belliard@chu-rennes.fr CHU de Rouen Hôpital Charles Nicolle Service Neurologie Not yet recruiting Rouen, France, 76031 Contact: David Wallon 06.08.97.29.59 david.wallon@chu-rouen.fr Chu de Saint-Etienne, CMRR Not yet recruiting Saint-Étienne, France, 42055 Contact: Isabelle ROUCH 04.77.12.73.98 isabelle.rouch@chu-st-etienne.fr Chu de Strasbourg Hôpital Ka Robertsau Pôle de Gériatrie - CMRR Not yet recruiting Strasbourg, France, 67200 Contact: Frédéric BLANC 03.88.12.86.38 frederic.blanc@chru-strasbourg.fr Centre de Recherche Clinique du Gérontopôle Cité de la Santé Toulouse, France CHRU de Bretonneau Unité de gérontopsychiatrie Not yet recruiting Tours, France, 37000 Contact: Thomas DESMIDT 06.68.07.97.06 t.desmidt@chu-tours.fr CHU Nancy Service de Gériatrie-CMRR Not yet recruiting Vandoeuvre les nancy, France, 54511 Contact: Thérèse RIVASSEAU JONVAUX 03.83.15.35.71 t.jonveaux@chu-nancy.fr Hospice Civil de Lyon Hôpital des Charpennes Not yet recruiting Villeurbanne, France, 69100 Contact: Pierre KROLAK SALMON 04.72.43.20.50 pierre.krolak-salmon@chu-lyon.fr Collapse << |
| NCT01362686 | Dementia Alzh... more >>eimer's Disease Collapse << | Not Applicable | Terminated(Low study accrual c... more >>aused the study to be ended early.) Collapse << | - | United States, Indiana ... more >> Touchpoint Fishers, Indiana, United States, 46037 Methodist Center for Geriatric Medicine Indianapolis, Indiana, United States, 46202 University Clinical Neurology Indianapolis, Indiana, United States, 46202 Wishard Health Services Indianapolis, Indiana, United States, 46202 St. Vincent Center for Healthy Aging Indianapolis, Indiana, United States, 46260 Collapse << |
| NCT02860065 | Alzheimer's Disease | Phase 2 | Withdrawn | June 30, 2017 | United States, Michigan ... more >> Henry Ford Health System--West Bloomfield Hospital West Bloomfield Township, Michigan, United States, 48322 Collapse << |
| NCT00948909 | Alzheimer's Disease | Phase 2 | Completed | - | United States, California ... more >> Site Reference ID/Investigator# 19904 Fresno, California, United States, 93720 United States, Florida Site Reference ID/Investigator# 23025 West Palm Beach, Florida, United States, 33407 United States, Indiana Site Reference ID/Investigator# 19905 Indianapolis, Indiana, United States, 46260 Bulgaria Site Reference ID/Investigator# 22944 Pleven, Bulgaria, 5800 Site Reference ID/Investigator# 22942 Plovdiv, Bulgaria, 4000 Site Reference ID/Investigator# 22945 Sofia, Bulgaria, 1113 Site Reference ID/Investigator# 22946 Sofia, Bulgaria, 1431 Czech Republic Site Reference ID/Investigator# 20276 Litomerice, Czech Republic, 412 01 Site Reference ID/Investigator# 20273 Plzen, Czech Republic, 301 36 Site Reference ID/Investigator# 20274 Prague 10, Czech Republic, 100 00 Site Reference ID/Investigator# 20272 Prague 2, Czech Republic, 120 00 Site Reference ID/Investigator# 20701 Prague 5, Czech Republic, 15006 Slovakia Site Reference ID/Investigator# 23625 Bratislava, Slovakia, 82606 Site Reference ID/Investigator# 23624 Bratislava, Slovakia Site Reference ID/Investigator# 23622 Michalovce, Slovakia, 07101 Site Reference ID/Investigator# 23942 Rimavska Sobota, Slovakia, 979 12 South Africa Site Reference ID/Investigator# 20267 Belville, South Africa, 7530 Site Reference ID/Investigator# 20266 Cape Town, South Africa, 7500 Site Reference ID/Investigator# 20261 Durban, South Africa, 4001 Site Reference ID/Investigator# 21682 George, South Africa, 6529 Site Reference ID/Investigator# 20265 Johannesburg, South Africa, 2196 Site Reference ID/Investigator# 20271 Port Elizabeth, South Africa, 6001 Site Reference ID/Investigator# 20263 Richards Bay, South Africa, 3900 United Kingdom Site Reference ID/Investigator# 20187 Blackburn, United Kingdom, BB2 3HH Site Reference ID/Investigator# 20183 Bradford, United Kingdom, BD3 0DQ Site Reference ID/Investigator# 20191 Crowborough, United Kingdom, TN6 1HB Site Reference ID/Investigator# 20184 Glasgow, United Kingdom, G20 0XA Site Reference ID/Investigator# 20190 London, United Kingdom, TW8 8DS Site Reference ID/Investigator# 20192 Southampton, United Kingdom, SO30 3JB Collapse << |
| NCT00645190 | Alzheimer Disease | Phase 3 | Completed | - | - |
| NCT00043589 | Memory Disorders | Not Applicable | Completed | - | United States, California ... more >> Aging Clinical Research Center, VA Palo Alto Health Care System Palo Alto, California, United States, 94305 Collapse << |
| NCT01903824 | Cognitive Impairment | Phase 1 | Completed | - | Netherlands ... more >> Teva Investigational Site 38051 Leiden, Netherlands Collapse << |
| NCT01362686 | - | - | Terminated(Low study accrual c... more >>aused the study to be ended early.) Collapse << | - | - |
| NCT03030105 | Alzheimer Disease | Phase 1 | Completed | - | United States, Texas ... more >> ICON Early Phase Services, LLC Austin, Texas, United States, 78209 Collapse << |
| NCT00062972 | Multiple Sclerosis | Phase 3 | Withdrawn(Study terminated/wit... more >>hdrawn) Collapse << | - | United States, New York ... more >> University Hospital and Medical Center Stony Brook, New York, United States, 11794-8121 Collapse << |
| NCT00042172 | Cognition Disorders ... more >> Alzheimer Disease Collapse << | Phase 4 | Completed | - | United States, Iowa ... more >> University of Iowa Department of Psychiatry Iowa City, Iowa, United States, 52242 Collapse << |
| NCT00602680 | Alzheimer's Disease | Phase 2 | Terminated(Insufficient expect... more >>ed benefit risk) Collapse << | - | France ... more >> Sanofi-Aventis Administrative Office Paris, France Collapse << |
| NCT03011476 | Parkinson Disease | Phase 4 | Recruiting | December 30, 2018 | Korea, Republic of ... more >> Kyung Hee Universtiy Hospital Recruiting Seoul, Korea, Republic of, 02447 Contact: Su Jin Hahn, BA 82-2-958-9579 khcri@khmc.or.kr Contact: Kyung Wha Hahn, BA 82-2-958-9566 yynam@khmc.or.kr Collapse << |
| NCT03283059 | Alzheimer Disease | Phase 3 | Recruiting | February 16, 2020 | China, Shanghai ... more >> Shanghai Mental Health Center Recruiting Shanghai, Shanghai, China, 200030 Contact: Shifu Xiao, M.D., Ph.D. +86 21 64387250 ext 73441 xiaoshifu@msn.com Contact: Tao Wang, M.D., Ph.D. +86 18017311279 wtshhwy@163.com Collapse << |
| NCT01018875 | Alzheimer's Disease | Phase 2 | Completed | - | Russian Federation ... more >> Site Reference ID/Investigator# 22687 Kazan, Russian Federation, 420012 Site Reference ID/Investigator# 22636 Moscow, Russian Federation, 115522 Site Reference ID/Investigator# 23702 Moscow, Russian Federation, 123995 Site Reference ID/Investigator# 22689 Saratov, Russian Federation, 410060 Site Reference ID/Investigator# 22635 St. Petersburg, Russian Federation, 190005 Site Reference ID/Investigator# 22633 St. Petersburg, Russian Federation, 190103 Site Reference ID/Investigator# 22637 St. Petersburg, Russian Federation, 190121 Site Reference ID/Investigator# 22632 St. Petersburg, Russian Federation, 192019 Site Reference ID/Investigator# 22634 St. Petersburg, Russian Federation, 192019 Site Reference ID/Investigator# 24563 St. Petersburg, Russian Federation, 194044 Ukraine Site Reference ID/Investigator# 22630 Dnipropetrovs'k, Ukraine, 49027 Site Reference ID/Investigator# 22625 Donetsk, Ukraine Site Reference ID/Investigator# 22624 Glevakha, Ukraine, 08631 Site Reference ID/Investigator# 22629 Kharkiv, Ukraine, 61168 Site Reference ID/Investigator# 24565 Kherson, Ukraine, 73488 Site Reference ID/Investigator# 24566 Kiev, Ukraine, 04112 Site Reference ID/Investigator# 22622 Kiev, Ukraine, 04114 Site Reference ID/Investigator# 22623 Kiev, Ukraine, 05113 Site Reference ID/Investigator# 22628 Lugansk, Ukraine, 91045 Site Reference ID/Investigator# 43143 Odessa, Ukraine, 65006 Site Reference ID/Investigator# 22627 Poltava, Ukraine, 36006 Collapse << |
| NCT01137526 | Alzheimer's Disease | Phase 2 | Completed | - | Russian Federation ... more >> Site Reference ID/Investigator# 40834 Ekaterinburg, Russian Federation, 620030 Site Reference ID/Investigator# 36304 Kazan, Russian Federation, 420097 Site Reference ID/Investigator# 36306 Kirov, Russian Federation, 610014 Site Reference ID/Investigator# 37944 Moscow, Russian Federation, 119048 Site Reference ID/Investigator# 26909 Saratov, Russian Federation, 410060 Site Reference ID/Investigator# 26904 St. Petersburg, Russian Federation, 190005 Site Reference ID/Investigator# 26902 St. Petersburg, Russian Federation, 190103 Site Reference ID/Investigator# 36305 St. Petersburg, Russian Federation, 198510 Site Reference ID/Investigator# 38383 Yaroslavl, Russian Federation, 150030 South Africa Site Reference ID/Investigator# 45584 Belville, South Africa, 7530 Site Reference ID/Investigator# 47102 George, South Africa, 6529 Site Reference ID/Investigator# 45583 Johannesburg, South Africa, 2196 Ukraine Site Reference ID/Investigator# 39855 Donetsk, Ukraine, 83003 Site Reference ID/Investigator# 26914 Kharkiv, Ukraine, 61177 Site Reference ID/Investigator# 26912 Kiev, Ukraine, 04114 Site Reference ID/Investigator# 40484 Lviv, Ukraine, 79010 Site Reference ID/Investigator# 27002 Poltava, Ukraine, 36006 Site Reference ID/Investigator# 39856 Poltava, Ukraine, 36024 Site Reference ID/Investigator# 40482 Simferopil, Ukraine, 95006 Site Reference ID/Investigator# 40483 Ternopil, Ukraine, 46020 Site Reference ID/Investigator# 35660 Vinnytsia, Ukraine, 21005 United Kingdom Site Reference ID/Investigator# 36327 Bath, United Kingdom, BA1 3NG Site Reference ID/Investigator# 35657 Blackburn, United Kingdom, BB2 3HH Site Reference ID/Investigator# 36330 Crowborough, United Kingdom, TN6 1HB Site Reference ID/Investigator# 36326 Glasgow, United Kingdom, G20 0XA Site Reference ID/Investigator# 44123 Ivybridge, Devon, United Kingdom, PL21 9AB Site Reference ID/Investigator# 35658 London, United Kingdom, TW8 8DS Site Reference ID/Investigator# 35902 Northampton, United Kingdom, NN5 6UD Site Reference ID/Investigator# 36328 Oxford, United Kingdom, OX3 9DU Site Reference ID/Investigator# 36329 Peterborough, United Kingdom, PE2 7JU Collapse << |
| NCT00139373 | Supranuclear Palsy, Progressiv... more >>e Collapse << | Phase 2 | Unknown | - | France ... more >> Centre d'Investigation Clinique-HÔPITAL PITIÉ-SALPETRIERE Recruiting Paris, France, 75013 Contact: Marie-Laure Welter, MD 33-42161950 marie-laure.welter@psl.aphp.fr Contact: Bertrand Gaymard, MD, PhD 33-142162218 gaymard@ccr.jussieu.fr Principal Investigator: Bertrand Gaymard, MD, PhD Collapse << |
| NCT03090516 | Alzheimer's | Phase 2 Phase 3 | Recruiting | March 10, 2018 | China, Jiangsu ... more >> Ting Wu Recruiting Nanjing, Jiangsu, China, 210000 Contact: Ting Wu, professor 18851122018 wuting80000@126.com Contact: Wanrong Zhang, master 15851875395 zwr10010533@163.com Collapse << |
| NCT00315367 | Relapsing-Remitting Multiple S... more >>clerosis Collapse << | Phase 4 | Completed | - | United States, Wisconsin ... more >> Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226 Collapse << |
| NCT00104273 | Dementia Alzh... more >>eimer's Disease Collapse << | Phase 2 | Completed | - | - |
| NCT03151382 | Alzheimer Disease ... more >> Cognitive Function Collapse << | Phase 4 | Not yet recruiting | June 30, 2018 | - |
| NCT00142324 | Alzheimer's Disease | Phase 4 | Unknown | - | United Kingdom ... more >> Queen Elizabeth Psychiatric Hospital Birmingham, United Kingdom, B15 2QZ Department of Psychiatry for the Elderly, Leicester General Hospital Leicester, United Kingdom, LE5 4PW Institute of Psychiatry, King's College, London London, United Kingdom, SE5 8AF Old Age Psychiatry, Wythenshawe Hospital, Manchester Manchester, United Kingdom, M23 9LT Institute for Ageing and Health, Newcastle General Hospital, Newcastle Newcastle upon Tyne, United Kingdom, NE4 6BE Department of Psychiatry, Warneford Hospital, Oxford Oxford, United Kingdom, OX3 7JX MARC, Moorgreen Hospital, Southamptom Southampton, United Kingdom, S030 3JB Department of Old Age Psychiatry, Victoria Hospital, Swindon Swindon, United Kingdom, SN1 4HZ Collapse << |
| NCT00165724 | Alzheimer's Disease | Phase 4 | Completed | - | Korea, Republic of ... more >> Bobath Memorial Hospital Bundang, Korea, Republic of Bundang Seoul National University Hospital Bundang, Korea, Republic of Changwon Fatima Hospital Changwon, Korea, Republic of Yeungnam University Hospital Daegu, Korea, Republic of Inha University Hospital Incheon, Korea, Republic of Catholic University Hospital Seoul, Korea, Republic of Eulji University Hospital Seoul, Korea, Republic of Collapse << |
| NCT02035982 | Alzheimer's Disease ... more >> Dementia Collapse << | Phase 3 | Completed | - | Canada, Ontario ... more >> North York General Hospital Toronto, Ontario, Canada, M2K1E1 Sunnybrook Health Sciences Centre Toronto, Ontario, Canada, M4N 3M5 Collapse << |
| NCT02453932 | Vascular Dementia | Phase 3 | Completed | - | China, Beijing ... more >> Dongzhimen Hospital,Beijing University of Chinese Medicine Beijing, Beijing, China, 100700 Collapse << |
| NCT03569579 | Central Nervous System Disease... more >>s Collapse << | Phase 1 | Completed | - | Korea, Republic of ... more >> Chonbuk National University Hospital Jeonju, Korea, Republic of Collapse << |
| NCT00967707 | Post-traumatic Neuropathic Pai... more >>n Collapse << | Phase 2 | Completed | - | Sweden ... more >> Multidisciplinary Pain Centre, Uppsala University Hospital Uppsala, Sweden, 75185 Collapse << |
| NCT01379001 | Cholinergic Function | Not Applicable | Completed | - | - |
| NCT00069550 | Rett Syndrome | Phase 3 | Unknown | - | United States, Maryland ... more >> Kennedy Krieger Institute Recruiting Baltimore, Maryland, United States Contact: SakkuBai R. Naidu, MD 443-923-2778 Contact: Genila Bibat, MD 443-923-2778 bibat@kennedykrieger.org Collapse << |
| NCT01409564 | - | - | Completed | - | - |
| NCT00206947 | Schizophrenia | Phase 2 | Terminated(No more funding) | - | Denmark ... more >> Center for Neuropsychiatric Schizophrenia Research, University of Copenhagen, Dept. F, Bispebjerg Hospital Copenhagen NV, Denmark, DK-2400 Dept. of Psychiatry O, Rigshospitalet, Blegdamsvej 9 Copenhagen, Denmark, DK-2100 Psychiatric Center, Glostrup Glostrup, Denmark, DK-2600 Danish Research Center for Magnetic Resonance Imaging, Hvidovre Hospital Hvidovre, Denmark, DK-2650 Collapse << |
| NCT00000173 | Alzheimer Disease | Phase 3 | Completed | - | - |
| NCT00482001 | Mental Health ... more >> Geriatrics Collapse << | Phase 4 | Completed | - | Canada, Ontario ... more >> Lakehead University Thunder Bay, Ontario, Canada, P7B 5E1 Sunnybrook Health Sciences Centre Toronto, Ontario, Canada, M4N 3M5 Collapse << |
| NCT00467766 | Alzheimer Disease ... more >> Caregivers Collapse << | Not Applicable | Completed | - | United States, New York ... more >> Aging and Dementia Research Center, Silberstein Institute, NYU School of Medicine New York, New York, United States, 10016 Australia, New South Wales Prince of Wales Hospital Randwick, New South Wales, Australia, 2031 United Kingdom University of Manchester, Division of Psychiatry Manchester, United Kingdom, M23 9LT Collapse << |
| NCT01409564 | Alzheimer's Dementia | Phase 4 | Completed | - | Korea, Republic of ... more >> SMG-SNU Boramae Medical Center Seoul, Korea, Republic of, 156-707 Collapse << |
| NCT00369603 | Alzheimer's Disease | Phase 4 | Terminated(Reduced access to A... more >>chEI medication-naive mild AD patients.) Collapse << | - | United States, North Carolina ... more >> Joseph & Kathleen Bryan Alzheimer's Disease Research Unit Durham, North Carolina, United States, 27705 Collapse << |
| NCT00384423 | Alzheimer's Disease | Phase 2 | Completed | - | United States, California ... more >> California Clinical Trials Medical Group, Inc Paramount, California, United States, 90723 Southwest CLinical Research Rancho Mirage, California, United States, 94109 Pacific Research Network, Inc San Diego, California, United States, 92103 San Francisco Clinical Research Center San Francisco, California, United States, 94109 Torrance Clinical Research Torrance, California, United States, 90505 United States, Connecticut Research Center for Clinical Studies Darien, Connecticut, United States, 06820 United States, Florida Miami Jewish Home and Hospital for the Aged Miami, Florida, United States, 33137 Berma Research Plantation, Florida, United States, 33317 Meridien Research St Petersburg, Florida, United States, 33709 Comprehensive NeuroScience, Inc St. Petersburg, Florida, United States, 33702 United States, Georgia Atlanta Center for Medical Research Atlanta, Georgia, United States, 30308 United States, Louisiana J. Gary Booker, MD Shreveport, Louisiana, United States, 71104 United States, Massachusetts Neuroscience Research of the Berkshires Pittsfield, Massachusetts, United States, 01201 United States, Ohio Neurology Specialists Dayton, Ohio, United States, 45408 United States, Oklahoma Saint Johns Office Building Tulsa, Oklahoma, United States, 74104 United States, Pennsylvania The Clinical Trial Center, LLC Jenkintown, Pennsylvania, United States, 19046 United States, South Carolina Alliance for Neuro Research, LLC Greenville, South Carolina, United States, 29615 Collapse << |
| NCT00151398 | Alzheimer Disease | Phase 2 | Completed | - | - |
| NCT02648906 | Alzheimer Disease | Phase 4 | Unknown | - | Korea, Republic of ... more >> Seoul National University Bundang Hospital Recruiting Sungnam, Korea, Republic of Collapse << |
| NCT00586196 | - | - | Completed | - | - |
| NCT00586196 | Delirium | Phase 2 | Completed | - | United States, Massachusetts ... more >> Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 Collapse << |
| NCT02573519 | Diabetic Autonomic Neuropathy ... more >> Gastrointestinal Motility Disorder Diabetes Mellitus Change of Transit or Circulation Collapse << | Not Applicable | Recruiting | August 2019 | Denmark ... more >> Department of Hematology and Gastroenterology, Aarhus University Hospital Recruiting Aarhus, Denmark, 8000 Contact: Mette Winther Andersen +45 22635197 meteader@rm.dk Contact: Klaus Krogh, Professor +45 23385937 klaukrog@rm.dk Sub-Investigator: Anne-Mette Haase, P.hD. Sub-Investigator: Lotte Fynne, P.hD. Collapse << |
| NCT01772095 | - | - | Completed | - | Greece ... more >> Aiginition University Hospital Athens, Greece Collapse << |
| NCT00842816 | Alzheimer's Disease | Phase 2 | Completed | - | - |
| NCT02406261 | Healthy | Phase 1 | Completed | - | United States, Florida ... more >> Covance Inc Daytona Beach, Florida, United States, 32117 United States, Texas Covance Inc Dallas, Texas, United States, 75247 Collapse << |
| NCT00777608 | Alzheimer's Disease | Phase 1 | Completed | - | - |
| NCT00895895 | - | - | Terminated(See termination rea... more >>son in detailed description.) Collapse << | - | - |
| NCT00895895 | Alzheimer Disease | Phase 2 | Terminated(See termination rea... more >>son in detailed description.) Collapse << | - | - |
| NCT00777608 | - | - | Completed | - | - |
| NCT01658228 | Depression Mi... more >>ld Cognitive Impairment Collapse << | Phase 4 | Completed | - | United States, New York ... more >> New York State Psychiatric Institute New York, New York, United States, 10032 United States, North Carolina Duke University Durham, North Carolina, United States, 27710 Collapse << |
| NCT00480870 | Alzheimer Disease ... more >> Sleep Apnea, Obstructive Collapse << | Phase 4 | Completed | - | Brazil ... more >> Instituto do Sono Sao Paulo, Brazil, 04020-060 Collapse << |
| NCT01039701 | Mild to Moderate Alzheimer's D... more >>isease Collapse << | Phase 2 | Completed | - | Czech Republic ... more >> Research Site Litomerice, Czech Republic Research Site Praha 10 - Strasnice, Czech Republic Research Site Praha 10, Czech Republic Research Site Praha 6, Czech Republic Hungary Research Site Debrecen, Hungary Research Site Esztergom, Hungary Research Site Miskolc, Hungary Research Site Nagykallo, Hungary Research Site Nyiregyhaza, Hungary Research Site Szeged, Hungary Slovakia Research Site Bratislava, Slovakia Research Site Roznava, Slovakia Research Site Zlate Moravce, Slovakia Collapse << |
| NCT01658228 | - | - | Completed | - | - |
| NCT00015132 | Cocaine-Related Disorders | Phase 2 | Completed | - | United States, Ohio ... more >> Cincinnati MDRU Cincinnati, Ohio, United States, 45220 Collapse << |
| NCT01712074 | Alzheimer's Disease | Phase 2 | Terminated(The study was termi... more >>nated October 23, 2015 as pre-specified, interim analysis futility criteria were met. The termination was not due to safety concerns.) Collapse << | - | - |
| NCT00829374 | Alzheimer's Disease | Phase 3 | Completed | - | - |
| NCT00165815 | Dementia With Parkinson's Dise... more >>ase Collapse << | Phase 3 | Completed | - | Germany ... more >> Allgemeines Krankenhaus Barmbeck Hamburg, Hambug, Germany Parkinson Klinik Wolfach Wolfach, Germany Ireland Belfast City Hospital Belfast, Ireland Unit 20 Black Poo Technology Centerl Blackpool, Ireland Collapse << |
| NCT01972204 | Alzheimer's Type Dementia | Not Applicable | Unknown | - | Japan ... more >> Shonan Fujisawa Tokushukai Hospital Recruiting Tsujidoukandai 1-5-1, Fujisawa-City, Kanagawa, Japan Principal Investigator: Tetsumasa Kamei Collapse << |
| NCT00672945 | Alzheimer's Disease | Phase 2 | Terminated | - | - |
| NCT01712074 | - | - | Terminated(The study was termi... more >>nated October 23, 2015 as pre-specified, interim analysis futility criteria were met. The termination was not due to safety concerns.) Collapse << | - | - |
| NCT00165659 | Alzheimer Disease | Phase 2 | Completed | - | - |
| NCT02857244 | Parkinson's Disease | Phase 2 | Withdrawn(Site did not obtain ... more >>LIRB approval due to medication usage.) Collapse << | November 2017 | United States, Illinois ... more >> University of Chicago Medical Center Chicago, Illinois, United States, 60637 Collapse << |
| NCT02055703 | Healthy Subjects | Phase 1 | Completed | - | United States, Texas ... more >> WCT Early Development San Antonio, Texas, United States, 78217 Collapse << |
| 靶点 | Description | IC50 |
|---|---|---|
| AChE | IC50:11.6nM | |
| AChE (bovine) | IC50:8.12nM |
