CAS No.: 69-89-6
黄嘌呤 Catalog No. CSN19381
Synonyms: xanthine;Isoxanthine;1H-Purine-2,6(3H,7H)-Dione
Xanthine is a natural occuring purine-base adenosine receptor antagonist, from which a number of stimulants such as caffeine and theobromine are derived.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03680573 Cardiovascular Diseases ... more >> Cardiovascular Risk Factor Vasoconstriction Collapse << Phase 1 Completed - United States, Texas ... more >> Engineering Research Building Arlington, Texas, United States, 76019 Collapse << NCT03737409 Fibrotic Interstitial Lung Dis... more >>ease Collapse << Not Applicable Not yet recruiting December 1, 2023 Australia, Victoria ... more >> La Trobe University Not yet recruiting Melbourne, Victoria, Australia, 3181 Contact: Anne Holland, Professor +613 94796744 A.Holland@latrobe.edu.au Collapse << NCT02176460 Knee Osteoarthritis Phase 2 Phase 3 Completed - Singapore ... more >> Singapore General Hospital Singapore, Singapore, 169608 Collapse << - 更多
- 参考文献
- [1] Daly JW, Jacobson KA, Ukena D. Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63.
- [2] Smith SC, Wender SH. The use of amberlite resin in a separation of xanthine and guanine. J Am Chem Soc. 1948 Nov;70(11):3719.
- [3] Ashihara H, Mizuno K, Yokota T, Crozier A. Xanthine Alkaloids: Occurrence, Biosynthesis, and Function in Plants. Prog Chem Org Nat Prod. 2017;105:1-88
- [4] Pundir CS, Devi R. Biosensing methods for xanthine determination: a review. Enzyme Microb Technol. 2014 Apr 10;57:55-62
- [5] Stipek S, Novak L, Crkovska J, Zima T, Platenik J. Xanthine oxidoreductase. Biochemical, biological and pathogenic functions. Sb Lek. 1994;95(4):289-95
- [6] Flegel T, Freistadt R, Haider W. Xanthine urolithiasis in a dachshund. Vet Rec. 1998 Oct 10;143(15):420-3
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 69-89-6 | 储存条件 |
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| 分子式 | C5H4N4O2 | 运输 | 蓝冰 | |||
| 分子量 | 152.11 | 别名 | xanthine;Isoxanthine;1H-Purine-2,6(3H,7H)-Dione;2,6-Dihydroxypurine;NSC 14664;黄嘌呤 | |||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT03680573 | Cardiovascular Diseases ... more >> Cardiovascular Risk Factor Vasoconstriction Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> Engineering Research Building Arlington, Texas, United States, 76019 Collapse << |
| NCT03737409 | Fibrotic Interstitial Lung Dis... more >>ease Collapse << | Not Applicable | Not yet recruiting | December 1, 2023 | Australia, Victoria ... more >> La Trobe University Not yet recruiting Melbourne, Victoria, Australia, 3181 Contact: Anne Holland, Professor +613 94796744 A.Holland@latrobe.edu.au Collapse << |
| NCT02176460 | Knee Osteoarthritis | Phase 2 Phase 3 | Completed | - | Singapore ... more >> Singapore General Hospital Singapore, Singapore, 169608 Collapse << |
| NCT03218709 | Hyperuricemia | Phase 4 | Recruiting | April 2018 | China, Guangdong ... more >> Sun Yat-sen University Recruiting Guangzhou, Guangdong, China, 510080 Contact: Min Xia, Ph.D xiamin@mail.sysu.edu.cn Contact: Yi Guo, Ph.D guoyi_019@126.com Collapse << |
| NCT02790047 | Chronic Obstructive Pulmonary ... more >>Disease Collapse << | Not Applicable | Unknown | May 2018 | Thailand ... more >> School of Physical Therapy, Faculty of Associated Medical Sciences Not yet recruiting Muang Khon Kaen, Khon Kaen, Thailand, 40002 Srinagarind Hospital Recruiting Muang Khon Kaen, Khon Kaen, Thailand, 40002 Contact: Chatchai Phimphasak, M.Sc. (PT) +66861779571 chatmomo_chai@hotmail.com Collapse << |
| NCT00978653 | Hyperuricemia ... more >> Chronic Kidney Disease Collapse << | Not Applicable | Completed | - | Turkey ... more >> Istanbul Faculty of Medicine Istanbul, Turkey, 34390 Collapse << |
| NCT02529189 | Cardiovascular Diseases | Phase 2 | Recruiting | April 2021 | United Kingdom ... more >> William Harvey Research Institute, Barts and The London School of Medicine Recruiting London, United Kingdom, EC1M 6BQ Contact: Amrita Ahluwalia, BSc, PhD k.s.rathod@qmul.ac.uk Contact: Krishnaraj Rathod, MBBS k.s.rathod@qmul.ac.uk Principal Investigator: Anthony Mathur, MB BChir PhD Sub-Investigator: Krishnaraj S Rathod, MBBS Sub-Investigator: Daniel A Jones, MBBS PhD Sub-Investigator: Amy Robertson, BSc Sub-Investigator: Shanti Velmurugan, MBBS PhD Collapse << |
| NCT01363869 | Hyperuricemia ... more >> Gout Collapse << | Not Applicable | Completed | - | Thailand ... more >> Department of Internal Medicine, Faculty of Medicine, Chiang Mai University Chiang Mai, Thailand, 50200 Collapse << |
| NCT02217189 | Asthenozoospermia | Phase 2 | Completed | - | Iraq ... more >> Babylon University Hilla, Babylon, Iraq, 51002 Collapse << |
| NCT02999152 | Bone Metastasis ... more >> Malignant Hemopathy Collapse << | Not Applicable | Recruiting | December 31, 2019 | France ... more >> Institut de Cancérologie Lucien Neuwirth Recruiting Saint-Priest en Jarez, France, 42270 Principal Investigator: Nicolas Magné, PhD Sub-Investigator: Guy De Laroche, MD Sub-Investigator: Grégoire Pigne, MD Sub-Investigator: Denis Guyotat, PhD Sub-Investigator: Jérôme Cornillon, MD Institut Gustave Roussy Not yet recruiting Villejuif, France, 94800 Contact: Valentine Martin, MD Principal Investigator: Valentine Martin, MD Sub-Investigator: Angela Boros, MD Collapse << |
| NCT03316131 | Asymptomatic Hyperuricemia | Phase 2 | Completed | - | United States, California ... more >> Research Site Glendale, California, United States, 91206 United States, Maryland Research Site Baltimore, Maryland, United States, 21225 Collapse << |
| NCT02281799 | Pancreatitis ... more >>Inflammatory Bowel Diseases Collapse << | Phase 4 | Recruiting | January 2019 | Israel ... more >> Shaare Zedek Recruiting Jerusalem, Israel, 91031 Collapse << |
| NCT00763048 | - | - | Completed | - | - |
| NCT03418779 | IgA Nephropathy at High Risk o... more >>f Developing ESRD Collapse << | Phase 2 Phase 3 | Recruiting | August 31, 2021 | China, Beijing ... more >> Guang anmen Hospital, China Academy of Chinese Medical Sciences Recruiting Beijing, Beijing, China, 100053 Contact: Shen Li 010-88001057 lishen58173@163.com Contact: Jinpu Li +86 18642168989 Collapse << |
| NCT02047461 | Molybdenum Cofactor Deficiency... more >>, Type A Collapse << | Phase 2 | Active, not recruiting | June 2020 | United States, Wisconsin ... more >> Children's Hospital of Wisconsin Milwaukee, Wisconsin, United States, 53226 Australia Monash Medical Centre Melbourne, Australia Netherlands Beatrix Children's Hospital Groningen, Netherlands Tunisia Unité des maladies métaboliques Tunis, Tunisia United Kingdom Royal Hospital for Sick Children Glasgow, United Kingdom Collapse << |
| NCT00763048 | Gingival Diseases | Phase 3 | Completed | - | United States, Massachusetts ... more >> Forsyth Institute Boston, Massachusetts, United States, 02115 Collapse << |
| NCT03680638 | Cardiovascular Diseases ... more >> Cardiovascular Risk Factor Vasodilation Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> Engineering Research Building Arlington, Texas, United States, 76019 Collapse << |
| NCT02293824 | - | - | Completed | - | United States, North Carolina ... more >> North Carolina Children's Hospital Chapel Hill, North Carolina, United States, 27599 Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT02498652 | - | - | Completed | - | - |
| NCT02629393 | Molybdenum Cofactor Deficiency... more >>, Type A Collapse << | Phase 2 Phase 3 | Active, not recruiting | September 2020 | United States, Ohio ... more >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 United States, Wisconsin Children's Hospital of Wisconsin Milwaukee, Wisconsin, United States, 53226-4874 France CHU Lyon - Hôpital Femme Mère- Enfant Lyon, Rhone, France, 69677 Israel HaEmek Medical Center Afula, Israel, 18341 Malaysia Hospital Kuala Lumpur Kuala Lumpur, Malaysia, 50586 Spain Hospital Sant Joan de Deu Esplugues de Llobregat, Barcelona, Spain, 08950 Turkey Hacettepe University of Medicine Ankara, Turkey, 06100 Akdeniz University Medical Faculty Antalya, Turkey, 07058 United Kingdom Willink Biochemical Genetics Unit Manchester, Greater Manchester, United Kingdom, M13 9WL Collapse << |
| NCT00175019 | Gout | Phase 3 | Completed | - | - |
| NCT02498652 | Gout | Phase 2 | Completed | - | United States, California ... more >> Anaheim, California, United States, 92801 United States, Florida DeLand, Florida, United States, 32720 South Miami, Florida, United States, 33143 United States, Texas Dallas, Texas, United States, 75231 Collapse << |
| NCT00175019 | - | - | Completed | - | - |
| NCT02275884 | Parkinson Disease | Not Applicable | Unknown | June 2015 | Germany ... more >> Department of Neurology, Dresden University of Technology Recruiting Dresden, Saxony, Germany, 01307 Contact: Simone Schmidt +49 351 458 2524 ext 2524 simone.schmidt@uniklinikum-dresden.de Principal Investigator: Matthias Löhle, MD Sub-Investigator: Alexander Storch, MD Collapse << |
| NCT02170012 | Healthy Elderly | Phase 1 | Terminated(The study was prema... more >>turely terminated on 17th December 2014 due to safety concerns.) Collapse << | - | United States, Florida ... more >> Miami Research Associates, Inc. South Miami, Florida, United States, 33143 MRA Clinical Research, LLC South Miami, Florida, United States, 33143 Collapse << |
| NCT02185638 | Obesity | Not Applicable | Completed | - | Denmark ... more >> Department Of Human Nutrition, Faculty of Science, University of Copenhagen Frederiksberg, Denmark, 1958 Collapse << |
| NCT03040778 | Medication-related Osteonecros... more >>is of the Jaw Bisphosphonate-related Osteonecrosis of the Jaw Avascular Necrosis Collapse << | Phase 3 | Recruiting | January 2020 | United States, Alabama ... more >> University of Alabama at Birmingham Not yet recruiting Birmingham, Alabama, United States, 35242 Contact: Anthony Morlandt, DDS, MD 205-934-3435 Morlandt@uab.edu United States, Michigan University of Michigan Not yet recruiting Ann Arbor, Michigan, United States, 48109-0018 Contact: Brent Ward, DDS, MD 734-763-5963 bward@umich.edu United States, New York New York Center for Orthognathic and Maxillofacial Surgery Not yet recruiting Lake Success, New York, United States, 11042 Contact: Salvatore Ruggiero, DMD, MD 516-775-1818 drruggiero@nycoms.com United States, Washington University of Washington Recruiting Seattle, Washington, United States, 98195 Contact: Jasjit Dillon, DDS, MBBS 206-543-7722 dillonj5@uw.edu Collapse << |
| NCT02151617 | Healthy | Phase 1 | Completed | - | United States, Connecticut ... more >> New Haven Clinical Research Unit New Haven, Connecticut, United States, 06511 Collapse << |
| NCT03534037 | Hyperuricemia ... more >> Metabolic Syndrome Left Ventricular Diastolic Dysfunction Collapse << | Phase 4 | Active, not recruiting | March 2020 | Taiwan ... more >> Tri-service General Hospital, songshan branch Taipei, Songshan Dist., Taiwan, 105 Collapse << |
| NCT02187029 | Gout | Phase 1 | Terminated(B7911002 was premat... more >>urely discontinued due to a safety concern that led to decision to terminate the study on 10 Nov 2014) Collapse << | - | United States, Florida ... more >> MRA Clinical Research, LLC Miami, Florida, United States, 33143 Miami Research Associates, Inc. South Miami, Florida, United States, 33143 United States, Kansas Vince and Associates Clinical Research Inc. Overland Park, Kansas, United States, 66211 Vince and Associates Clinical Research, Inc. Overland Park, Kansas, United States, 66212 Collapse << |
| NCT02060552 | Primary Gout | Phase 4 | Completed | - | China, Hubei ... more >> Yikai YU Wuhan, Hubei, China, 430030 Collapse << |
| NCT02187029 | - | - | Terminated(B7911002 was premat... more >>urely discontinued due to a safety concern that led to decision to terminate the study on 10 Nov 2014) Collapse << | - | - |
| NCT00174941 | Gout | Phase 2 | Completed | - | - |
| NCT02082769 | Gout | Phase 3 | Completed | - | - |
| NCT00174967 | - | - | Completed | - | - |
| NCT00174941 | - | - | Completed | - | - |
| NCT00188968 | Apnea Infant,... more >> Premature Bronchopulmonary Dysplasia Collapse << | Phase 3 | Completed | - | Canada, Manitoba ... more >> Health Sciences Centre Winnipeg, Manitoba, Canada, R3A 1R9 St. Boniface General Hospital Winnipeg, Manitoba, Canada Collapse << |
| NCT00174967 | Gout | Phase 2 | Completed | - | - |
| NCT02082769 | - | - | Completed | - | - |
| NCT03511248 | Heart Failure ... more >> Heart Failure, Systolic Collapse << | Phase 2 | Recruiting | December 2020 | United Kingdom ... more >> Queen Mary University of London Recruiting London, United Kingdom Contact: Prof Amrita Ahluwalia, BSc PhD a.ahluwalia@qmul.ac.uk Contact: Dr Christopher P Primus, MBBS BSc MRCP c.primus@qmul.ac.uk Principal Investigator: Amrita Ahulwalia, BSc PhD Sub-Investigator: Christopher P Primus, MBBS BSc MRCP Principal Investigator: Simon Woldman, MD FESC FRCP Principal Investigator: Ceri Davies, MD FRCP FESC Sub-Investigator: Charlotte Manisty, MBBS PhD MRCP Sub-Investigator: Shanti Velmurugan, MBBS PhD MRCP Sub-Investigator: Clement Lau, MBChB BMedSci MRCP Sub-Investigator: Krishnaraj Rathod, MBBS BMedSci MRCP Collapse << |
| NCT00102440 | - | - | Completed | - | - |
| NCT01228903 | - | - | Completed | - | - |
| NCT03680404 | Cardiovascular Diseases ... more >> Cardiovascular Risk Factor Vasoconstriction Collapse << | Phase 1 | Not yet recruiting | October 1, 2019 | United States, Texas ... more >> Engineering Research Building Not yet recruiting Arlington, Texas, United States, 76019 Contact: R. Matthew Brothers, PhD 8172723156 matthew.brothers@uta.edu Contact: John D Akins, MS 8172721835 john.akins@uta.edu Collapse << |
| NCT00102440 | Gout | Phase 3 | Completed | - | - |
| NCT02338323 | Chronic Kidney Disease ... more >> Hyperuricemia Abnormal Renal Function Collapse << | Not Applicable | Unknown | December 2018 | China, Shanghai ... more >> Department of Nephrology & Rheumatology, Shanghai Tenth People's Hospital Recruiting Shanghai, Shanghai, China, 200072 Contact: Ai Peng, MD, PhD pengai@tongji.edu.cn Contact: Ling Wang, MD, PhD nowax@126.com Sub-Investigator: Ling Wang, MD, PhD Collapse << |
| NCT02147002 | Chronic Kidney Disease ... more >> Cardiovascular Complications Collapse << | Not Applicable | Unknown | December 2014 | Poland ... more >> 1Katedra i Klinika Nefrologii, Nadciśnienia Tętniczego i Chorób Wewnętrznych, Bydgoszcz Recruiting Bydgoszcz, Kujawsko-pomorskie, Poland, 85-094 Contact: Agnieszka Pluta, dr 693716980 ext 0048 agnieszkapluta@poczta.onet.pl Principal Investigator: Paweł Stróżecki, dr Collapse << |
| NCT02944214 | Chronic Kidney Disease ... more >> Hyperuricemia Abnormal Renal Function Collapse << | Not Applicable | Not yet recruiting | December 2019 | China, Shanghai ... more >> Department of Nephrology & Rheumatology, Shanghai Tenth People's Hospital Not yet recruiting Shanghai, Shanghai, China, 200072 Contact: Ai Peng, MD, PhD pengai@tongji.edu.cn Collapse << |
| NCT01228903 | Kidney Disease | Not Applicable | Completed | - | United States, Colorado ... more >> University of Colorado at Denver Aurora, Colorado, United States, 80045 Collapse << |
| NCT03361618 | Infertility Unexplained | Not Applicable | Completed | - | Iraq ... more >> Mahmoud Hussein Hadwan Hilla, Babylon, Iraq, 51002 Collapse << |
| NCT02214589 | Prevention of Procedural Pain ... more >> Reduction of Procedural Pain Biochemical Effects of Oral Sucrose Collapse << | Not Applicable | Recruiting | July 2019 | United States, California ... more >> Loma Linda University Children's Hospital Recruiting Loma Linda, California, United States, 92354 Contact: Danilyn M Angeles, PhD 909-558-7563 dangeles@llu.edu Collapse << |
| NCT01894659 | Neonatal Procedural Pain | Not Applicable | Active, not recruiting | June 2019 | United States, California ... more >> Loma Linda University Medical Center Loma Linda, California, United States, 92354 Collapse << |
| NCT00664001 | Acute Mountain Sickness | Phase 3 | Completed | - | United Kingdom ... more >> University of Edinburgh Edinburgh, United Kingdom Collapse << |
| NCT03731741 | Anemia of Chronic Kidney Disea... more >>se Collapse << | Phase 2 | Completed | - | Egypt ... more >> Tanta university hospital Tanta, Egypt Collapse << |
| NCT00948194 | Liver Transplantation ... more >> Ischemia/Reperfusion Injury Oxidative Injury Collapse << | Not Applicable | Completed | - | United States, Colorado ... more >> University of Colorado Hospital Aurora, Colorado, United States, 80045 Collapse << |
| NCT03326167 | - | - | Recruiting | December 15, 2019 | France ... more >> Service de Médecine Nucléaire - Hôpital Louis Pradel - Hospices Civils de Lyon Recruiting Bron, France, 69677 Contact: Marc JANIER, PU-PH 0472357227 ext +33 marc.janier@chu-lyon.fr Principal Investigator: Marc JANIER, PU-PH Collapse << |
| NCT01701622 | Blood Pressure ... more >> Gout Collapse << | Not Applicable | Terminated(unable to enroll pa... more >>rticipants) Collapse << | - | United States, Mississippi ... more >> University of Mississippi Medical Center General Medicine/Hypertension and Family Medicine Clinics Jackson, Mississippi, United States, 39216 Collapse << |
| NCT01701622 | - | - | Terminated(unable to enroll pa... more >>rticipants) Collapse << | - | - |
| NCT00164112 | Healthy | Phase 4 | Completed | - | - |
| NCT01735188 | - | - | Completed | - | - |
| NCT02202239 | Hemodynamics ... more >>Oxidative Stress Anesthesia Collapse << | Phase 4 | Unknown | August 2015 | - |
| NCT02451774 | Acute Lymphoblastic Leukemia | Phase 2 Phase 3 | Recruiting | December 2020 | Mexico ... more >> Hospital Civil de Guadalajara "Dr. Juan I. Menchaca" Recruiting Guadalajara, Jalisco, Mexico, 44340 Contact: Ramon O Gonzalez Ramella, PhD 5213331719826 glezramella@hotmail.com Contact: Fabiola P Medina Barajas, PhD 5213313461917 favyri@hotmail.com Collapse << |
| NCT00477789 | Chronic Heart Failure | Phase 4 | Completed | - | Italy ... more >> Division of Cardiology, University Hospital of Verona Verona, Italy, 37129 Collapse << |
| NCT03700645 | Diabetes Mellitus ... more >> Ischemic Heart Disease Multi Vessel Coronary Artery Disease Collapse << | Phase 4 | Not yet recruiting | January 31, 2020 | - |
| NCT01894165 | Molybdenum Cofactor Deficiency... more >> (MoCD) Rare Autosomal Recessive Disorder Deficiency of Activity of Molybdenum-dependent Enzymes (Sulfite Oxidase [SOX], Xanthine Dehydrogenase, and Aldehyde Oxidase) Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> Parexel Baltimore EPCU Baltimore, Maryland, United States, 21225 Collapse << |
| NCT02600780 | Hyperuricemia | Phase 4 | Completed | - | Pakistan ... more >> Dow University of Health Sciences Karachi, Sindh, Pakistan, 74900 Collapse << |
| NCT03162653 | Encephalopathy, Hypoxic-Ischem... more >>ic Infant, Newborn, Diseases Collapse << | Phase 3 | Recruiting | December 2020 | Austria ... more >> Medizinische Universitaet Wien Active, not recruiting Wien, Austria, 1090 Belgium Katholieke Universiteit Leuven Active, not recruiting Leuven, Belgium, 3000 Estonia Tartu Ulikool Not yet recruiting Tartu, Estonia, 50090 Contact: Renata Poláčková, Prof. Dr. Finland Helsingin Ja Uudenmaan Sairaanhoitopiirin Kuntayhtymä Active, not recruiting Helsinki, Finland, 00029 Germany University Hospital Tübingen Recruiting Tübingen, Germany, 72076 Contact: Axel R Franz, MD +49707129 ext 0 albino@med.uni-tuebingen.de Contact: Gabriele von Oldershausen +49707129 ext 0 albino@med.uni-tuebingen.de Principal Investigator: Axel R Franz, MD Sub-Investigator: Christian Maiwald, MD Sub-Investigator: Jörg Arand, MD Italy Universita Degli Studi Di Udine Active, not recruiting Udine, Italy, 33100 Netherlands Universitair Medisch Centrum Utrecht Recruiting Utrecht, Netherlands, 3584 CX Contact: Manon Benders, Prof. MD PhD Norway Oslo Universitetssykehus Hf Active, not recruiting Oslo, Norway, 0450 Poland Uniwersytet Medyczny Im Karola Marcinkowskiego W Poznaniu Active, not recruiting Poznań, Poland, 61701 Portugal Universidade Do Porto Not yet recruiting Porto, Portugal, 4099 002 Contact: Hercilia Guimarães, Prof. MD PhD Spain Para La Investigacion Del Hospital UniversitarioLa Fe De La Comunidad Valenciana Not yet recruiting Valencia, Spain, 46026 Contact: Maximo Vento, Prof. MD PhD Switzerland Universitaet Zuerich Not yet recruiting Zuerich, Switzerland, 8006 Contact: Dirk Bassler, Prof. Dr. Collapse << |
| NCT01736514 | Gout | Phase 3 | Completed | - | Taiwan ... more >> Kaohsiung, Taiwan Linkou, Taiwan Taichung, Taiwan Taipei, Taiwan Collapse << |
| NCT02095405 | Supraventricular Tachycardia (... more >>SVT) Atrial Fibrillation Collapse << | Not Applicable | Completed | - | Canada, Ontario ... more >> University of Ottawa Heart Institute Ottawa, Ontario, Canada, K1Y 4W7 Collapse << |
| NCT02373384 | Urolithiasis ... more >>Renal Stones Collapse << | Phase 4 | Completed | - | Egypt ... more >> Urology and Nephrology Center Mansoura, DK, Egypt, 35516 Collapse << |
| NCT03512496 | Nutrition Ped... more >>iatric Obesity Pediatric Caffeine Metabolism Disorder, Glucose Health Behavior Glucose Intolerance Collapse << | Not Applicable | Recruiting | December 1, 2020 | Canada, Alberta ... more >> University of Calgary Recruiting Calgary, Alberta, Canada, T2N 1N4 Contact: Shyamchand Mayengbam, PhD 4032203431 shyamchandsingh.maye@ucalgary.ca Collapse << |
| NCT01052272 | Diabetes | Phase 2 Phase 3 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294-2180 Collapse << |
| NCT01052272 | - | - | Completed | - | - |
| NCT00997542 | Chronic Heart Failure ... more >> Hyperuricemia Collapse << | Phase 4 | Completed | - | United Kingdom ... more >> Royal Brompton Hospital London, United Kingdom, SW3 6NP Collapse << |
| NCT01320722 | - | - | Completed | - | - |
| NCT00241839 | - | - | Completed | - | - |
| NCT00174915 | Gout | Phase 3 | Completed | - | - |
| NCT01320722 | Renal Function ... more >> Endothelial Function Blood Pressure Overweight Obesity Collapse << | Phase 3 | Completed | - | United States, Massachusetts ... more >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Collapse << |
| NCT01799018 | - | - | Completed | - | United States, New York ... more >> State University of New York Upstate Medical University Syracuse, New York, United States, 13210 Collapse << |
| NCT02752633 | - | - | Completed | - | - |
| NCT00174915 | - | - | Completed | - | - |
| NCT01550107 | Sarcopenia | Phase 4 | Completed | - | United Kingdom ... more >> University of Dundee Medical School Dundee, Angus, United Kingdom, DD1 9SY Collapse << |
| NCT01794078 | Acute Mountain Sickness and Fa... more >>tigue Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> Duke Center for Hyperbaric Medicine Durham, North Carolina, United States, 27710 Duke Clinical Research Unit (DCRU) Durham, North Carolina, United States, 27710 Collapse << |
| NCT01157936 | Systolic and Diastolic Blood P... more >>ressure Levels Uric Acid Levels Metabolic Syndrome Parameters Hepatic Enzymes Collapse << | Phase 2 | Completed | - | Mexico ... more >> Insituto Nacional de Cardiología Ignacio Chávez Mexico, Mexico, 14080 Collapse << |
| NCT01784536 | Healthy | Phase 1 | Completed | - | United States, Wisconsin ... more >> Spaulding Clinical West Bend, Wisconsin, United States, 53095 Collapse << |
| NCT01472692 | Prehypertension ... more >> Gout Pulse Wave Velocity Hypertension 24 Hour Blood Pressure Collapse << | Phase 4 | Completed | - | United States, California ... more >> Univerisity Of California San Diego San Diego, California, United States, 92037 Collapse << |
| NCT03226899 | Gout Chronic ... more >>Kidney Disease (CKD) Collapse << | Phase 4 | Recruiting | December 2022 | - |
| NCT00987415 | Heart Failure ... more >> Elevated Serum Uric Acid Collapse << | Phase 2 | Completed | - | United States, Georgia ... more >> Morehouse School of Medicine Atlanta, Georgia, United States United States, Massachusetts Harvard University Boston, Massachusetts, United States United States, Minnesota University of Minnesota Minneapolis, Minnesota, United States Mayo Clinic Rochester, Minnesota, United States United States, North Carolina Duke University Medical Center Durham, North Carolina, United States United States, Ohio University Hospitals-Case Medical Center Cleveland, Ohio, United States, 44106 United States, Texas Baylor College of Medicine Houston, Texas, United States United States, Utah Univ. of Utah Health Sciences Center Salt Lake City, Utah, United States United States, Vermont University of Vermont Burlington, Vermont, United States Canada University of Montreal Montreal PQ, Canada Collapse << |
| NCT00987415 | - | - | Completed | - | - |
| NCT00214084 | Obstructive Sleep Apnea | Not Applicable | Withdrawn | - | United States, Wisconsin ... more >> University of Wisconsin Madison, Wisconsin, United States, 53792 Collapse << |
| NCT01987570 | Patients With Grade II Ankle S... more >>prain Collapse << | Phase 3 | Completed | - | Spain ... more >> University of Valencia Valencia, Spain, 46010 Hospital Universitari i Politècnic La Fe Valencia, Spain, 46026 Collapse << |
| NCT00181155 | Congestive Heart Failure | Phase 2 | Completed | - | United States, Maryland ... more >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 Collapse << |
| NCT00181155 | - | - | Completed | - | - |
| NCT03395977 | Oxidative Stress ... more >> Endothelial Function Cardiovascular System Hypertension Collapse << | Not Applicable | Recruiting | December 31, 2020 | Belgium ... more >> Erasme Hospital Recruiting Brussels, Belgique, Belgium, 1070 Contact: Benjamin De Becker +32474328542 Benjamin.De.Becker@erasme.ulb.ac.be Principal Investigator: Benjamin De Becker Collapse << |
| NCT01508702 | Gout | Phase 3 | Completed | - | - |
| NCT02752633 | Adenine Phosphoribosyltransfer... more >>ase Deficiency Collapse << | Phase 4 | Completed | - | Iceland ... more >> Landspitali - The National University Hospital of Iceland Reykjavik, Iceland, 101 Collapse << |
| NCT00688480 | Kidney Disease ... more >> Left Ventricular Hypertrophy Collapse << | Phase 4 | Completed | - | United Kingdom ... more >> Division of Medicine and Therapeutics, Ninewells Hospital & Medical School Dundee, United Kingdom, DD1 9SY Collapse << |
| NCT02122718 | Ischaemic Stroke | Phase 4 | Recruiting | September 2020 | United Kingdom ... more >> Altnagelvin Campus Recruiting Londonderry, County Derry, United Kingdom, BT47 6SB Contact: John Corrigan, MD Broomfield Hospital Recruiting Chelmsford, Essex, United Kingdom, CM1 7ET Contact: Ramanathan Kirthivasan, MD 01245 514746 Ramanathan.Kirthivasan@meht.nhs.uk Southend University Hospital Recruiting Westcliff-on-Sea, Essex, United Kingdom, SS0 0RY Contact: Paul Guyler, MD paul.guyler@southend.nhs.uk Darent Valley Hospital Recruiting Dartford, Kent, United Kingdom, DA2 8DA Contact: Imran Ashraf The Royal London Hospital Recruiting Whitechapel, London, United Kingdom, E1 1BB Contact: Sageet Amlani, MD Northumbria NHS Trust Recruiting Ashington, Northumberland, United Kingdom, NE63 9JJ Contact: Christopher Price Royal United Hospital Recruiting Bath, Somerset, United Kingdom, BA1 3NG Contact: Louise Shaw, MD louisej.shaw@nhs.net Royal Stoke University Hosptial Suspended Stoke-on-Trent, Staffordshire, United Kingdom, ST4 6QG NHS Grampian Recruiting Aberdeen, United Kingdom, AB25 2ZD Contact: Mary MacLeod NHS Lanarkshire Recruiting Airdrie, United Kingdom, ML6 0JS Contact: Mark Barber NHS Tayside Recruiting Dundee, United Kingdom, DD1 9SY Contact: Allan Struthers South West Acute Hospital Recruiting Enniskillen, United Kingdom, BT74 6DN Contact: Breffi Keegan, MD 02866382000 Breffni.Keegan@westerntrust.hscni.net NHS Greater Glagsow and Clyde Recruiting Glasgow, United Kingdom, G11 6NT Contact: Jesse Dawson Leeds Teaching Hospitals NHS Trust Recruiting Leeds, United Kingdom, LS1 3EX Contact: Ahamad Hassan Barnet Hospital Suspended London, United Kingdom, EN5 3DJ Guys and St Thomas NHS Foundation Trust Recruiting London, United Kingdom, SE1 7EH Contact: Ajay Bhalla UCL Stroke Research Centre Recruiting London, United Kingdom, WC1B 5EH Contact: David Werring, MD Luton and Dunstable University Hosptial Recruiting Luton, United Kingdom, LU4 0DZ Contact: Lakshmanan Sekaran, MD Newcastle UPon Tyne Hospitals NHS Trust Recruiting Newcastle, United Kingdom, NE2 4AB Contact: Alezander Dyker Nottingham University Recruiting Nottingham, United Kingdom, NG5 1PB Contact: Ganesh Subramanian City Hospital Sunderland NHS Foundation Trust Recruiting Sunderland, United Kingdom, SR4 7TP Contact: Naweed Sattar Collapse << |
| NCT02533648 | Type 2 Diabetes Mellitus | Phase 3 | Unknown | May 2016 | France ... more >> CRNH Rhône Alpes Recruiting Lyon, France, 69310 Contact: Martine LAVILLE, Professor +33. 4 78 86 29 81 martine.laville@chu-lyon.fr Contact: Nathalie FEUGIER +33. 4 78 86 19 72 nathalie.feugier@chu-lyon.fr Principal Investigator: Martine LAVILLE, professor Collapse << |
| NCT01830725 | - | - | Completed | - | United States, Mississippi ... more >> Keesler Medical Center Keesler AFB, Mississippi, United States, 39564 Collapse << |
| NCT01639534 | - | - | Completed | - | United States, Virginia ... more >> Virginia Commonwealth University Richmond, Virginia, United States, 23298 Collapse << |
| NCT01508702 | - | - | Completed | - | - |
| NCT01332799 | Complications of Renal Transpl... more >>ant Collapse << | Phase 4 | Active, not recruiting | March 2018 | United States, Iowa ... more >> University of Iowa Hospitals and Clinics Iowa City, Iowa, United States, 52240 Collapse << |
| NCT00241839 | Cardiovascular Diseases ... more >> Heart Diseases Hypertension Collapse << | Phase 3 | Completed | - | United States, Florida ... more >> University of Florida Gainesville, Florida, United States, 32610 Collapse << |
| 靶点 | Description | IC50 |
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