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CAS No.: 59729-37-2
Synonyms: HOE 239;非昔硝唑
Fexinidazole is a 5-nitroimidazole drug for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02571062 | Trypanosomiasis, African | Phase 1 | Completed | - | France ... more >> Biotrial Rennes, France Collapse << |
NCT02498782 | Chagas Disease ... more >> Trypanosomiasis, South American South American Trypanosomiasis Disease, Chagas Collapse << | Phase 2 | Unknown | February 2016 | Bolivia ... more >> Plataforma Atención Integral de Pacientes con Enfermedad de Chagas Recruiting Cochabamba, Bolivia Contact: Faustino Torrico, MD 59177411905 foxtorrico@yahoo.com Contact: Cristina Alonso, MD 59172211312 calonso@dndi.org Principal Investigator: Faustino Torrico, MD Plataforma de Atención Integral de Pacientes con Enfermedad de Chagas Recruiting Tarija, Bolivia Contact: Lourdes O Daza, MD 5916672252 lourdesortizd@yahoo.es Contact: Erika Ribeiro, Pharm D 59175969924 ecorreia@dndi.org Principal Investigator: Lourdes O Daza, MD Collapse << |
NCT01483170 | Trypanosomiasis, African | Phase 1 | Terminated(poor tolerability a... more >>t highest dose) Collapse << | - | France ... more >> SGS Life Sciences Paris, France, 75015 Collapse << |
实验方案
技术信息
CAS号 | 59729-37-2 | 储存条件 |
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分子式 | C12H13N3O3S | 运输 | 蓝冰 | |||||||
分子量 | 279.31 | 别名 | HOE 239;非昔硝唑 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02571062 | Trypanosomiasis, African | Phase 1 | Completed | - | France ... more >> Biotrial Rennes, France Collapse << |
NCT02498782 | Chagas Disease ... more >> Trypanosomiasis, South American South American Trypanosomiasis Disease, Chagas Collapse << | Phase 2 | Unknown | February 2016 | Bolivia ... more >> Plataforma Atención Integral de Pacientes con Enfermedad de Chagas Recruiting Cochabamba, Bolivia Contact: Faustino Torrico, MD 59177411905 foxtorrico@yahoo.com Contact: Cristina Alonso, MD 59172211312 calonso@dndi.org Principal Investigator: Faustino Torrico, MD Plataforma de Atención Integral de Pacientes con Enfermedad de Chagas Recruiting Tarija, Bolivia Contact: Lourdes O Daza, MD 5916672252 lourdesortizd@yahoo.es Contact: Erika Ribeiro, Pharm D 59175969924 ecorreia@dndi.org Principal Investigator: Lourdes O Daza, MD Collapse << |
NCT01483170 | Trypanosomiasis, African | Phase 1 | Terminated(poor tolerability a... more >>t highest dose) Collapse << | - | France ... more >> SGS Life Sciences Paris, France, 75015 Collapse << |
NCT02169557 | Human African Trypanosomiasis ... more >>(HAT) Collapse << | Phase 2 Phase 3 | Unknown | April 2017 | Congo, The Democratic Republic... more >> of the Kinshasa, Congo, The Democratic Republic of the Collapse << |
NCT02184689 | Human African Trypanosomiasis ... more >>(HAT) Collapse << | Phase 2 Phase 3 | Unknown | July 2017 | Congo, The Democratic Republic... more >> of the Kinshasa, Congo, The Democratic Republic of the Collapse << |
NCT01685827 | Human African Trypanosomiasis ... more >>(HAT) Sleeping Sickness Collapse << | Phase 2 Phase 3 | Completed | - | Central African Republic ... more >> Batangafo Batangafo, Central African Republic Congo, The Democratic Republic of the Bagata Hospital Bagata, Bandundu, Congo, The Democratic Republic of the Congo Masi Manimba Hospital Masi Manimba, Bandundu - DRC, Congo Vanga Hospital Vanga, Bandundu - DRC, Congo HGR Mushie hospital Mushie, Bandundu, Congo CRT (Centre de Réference et de Traitement) Dipumba, Dipumba general hospital Mbuji Mayi, East Kasai, Congo HS Katanda hospital Katanda, Kasaï Oriental, Congo HGR ISANGI hospital Isangi, Province Orientale, Congo HGR (General Reference Hospital) Bandundu Bandundu, Congo Dingila Dingila, Congo Collapse << |
NCT03025789 | Trypanosomiasis, African ... more >> Sleeping Sickness Trypanosomiasis; Gambian Collapse << | Phase 3 | Recruiting | March 2020 | Congo, The Democratic Republic... more >> of the Hôpital de Dipumba Recruiting Mbuji-Mayi, Kasaï Oriental, Congo, The Democratic Republic of the Contact: Dieudonné Mpoyi, Doctor dmpoyi@dndi.org Contact: Médard Ilunga, Doctor milunga@dndi.org Principal Investigator: Dieudonné Mpoyi, Doctor Sub-Investigator: Médard Ilunga, Doctor Hopital General de réference Recruiting Bagata, Congo, The Democratic Republic of the Contact: Papy Kavunga, MD plukula@dndi.org Principal Investigator: Papy Kavunga, Doctor Sub-Investigator: Mathieu Nkeri, Doctor Sub-Investigator: John Twampo, Doctor Hopital Général de réference Recruiting Bandundu, Congo, The Democratic Republic of the Contact: Helen Mahenzi, MD hmahenzi@dndi.org Principal Investigator: Helene Mahenzi, Doctor Sub-Investigator: Joseph MAKAYA, Doctor Sub-Investigator: Bedel Mulumba, Doctor Hopital de Kimpese Recruiting Kimpese, Congo, The Democratic Republic of the Contact: Jean-Papa Mavakala, Dr jpmavakala@dndi.org Principal Investigator: Jean-Papa Mavakala, Dr Hôpital Général de Référence Roi Baudouin Recruiting Kinshasa, Congo, The Democratic Republic of the Contact: Luwawu Ntoya, Doctor lntoya@dndi.org Principal Investigator: Luwawu Ntoya, Doctor Sub-Investigator: Vincent Kobo, Doctor Hopital Genral de Reference Masi MAnimba Recruiting Masi-Manimba, Congo, The Democratic Republic of the Contact: Willy Kuziena, Doctor Principal Investigator: Willy Kuziena Mindele, Doctor Sub-Investigator: Augustin Kukembila Musoki, Doctor Sub-Investigator: Felix Akwaso Masa, Doctor Hopital General de réference Recruiting Mushie, Congo, The Democratic Republic of the Contact: Guylain Mandula, MD gmandula@dndi.org Principal Investigator: Guylain Mandula, Doctor Sub-Investigator: Tim Mayala, Doctor HGR Nkara Recruiting Nkara, Congo, The Democratic Republic of the Contact: Steve Inzodi, Dr sinzodi@dndi.org Principal Investigator: Steve Inzodi, Dr Guinea Hopital de Dubreka Recruiting Dubreka, Guinea Contact: Mariame Camara, Dr mcamara@dndi.org Principal Investigator: Mariame Camara, Dr Collapse << |
NCT01980199 | Visceral Leishmaniasis | Phase 2 | Terminated(Lack of efficacy) | - | Sudan ... more >> Doka Hospital Doka, Gedaref, Sudan Collapse << |
NCT03587766 | Chagas' Disease (Chronic) Nos | Phase 2 | Recruiting | December 2019 | Spain ... more >> Hospital Clinic Recruiting Barcelona, Catalunia, Spain, 08036 Contact: Maria Jesús Pinazo, MD +34932275400 mariajesus.pinazo@isglobal.org Contact: Elizabeth de Jesus Posada, MD +34932275400 elizabeth.posada@isglobal.org Sub-Investigator: Irene Losada, MD Collapse << |
NCT01340157 | PK in Healthy Volunteers | Phase 1 | Completed | - | France ... more >> SGS Aster s.a.s. Paris, France, 75015 Collapse << |
NCT00982904 | Human African Trypanosomiasis | Phase 1 | Completed | - | France ... more >> SGS Aster Paris, France, 75015 Collapse << |
靶点 | Description | IC50 |
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