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CAS No.: 93106-60-6

恩诺沙星 Catalog No. CSN13081

Synonyms: BAY Vp 2674;PD160788;ENR

Enrofloxacin is a fluoroquinolone antibiotic used as a veterinary antibacterial agent.

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技术信息

生物活性

描述Enrofloxacin (EF) is an extensively used animal-specific antibacterial agent that leaves drug residues in the environment^[3]. The in vivo effectiveness of enrofloxacin against E. coli in different organs varied, with the Emax ranging from - 4.4 to - 5.8 Log10 colony forming units (cfu)/mL or cfu/g. The AUC0-24/MIC ratio of the combination of enrofloxacin and ciprofloxacin producing bactericidal and elimination effects were 21.29 and 32.13 in blood; 41.68, and 58.52 in the liver; and 27.65 and 46.22 in the lung, respectively^[4]. The most effective antibiotics tested in vitro were fluoroquinolones (MIC90 danofloxacin 0.312 μg/mL, enrofloxacin 0.312 μg/mL, marbofloxacin 0.625 μg/mL)^[5]. Enrofloxacin reduced C. jejuni cell densities within the cecal and colonic digesta for all treatments, and densities shed in feces as a function of antibiotic duration^[6].
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03575312	Healthy	Not Applicable	Completed	-	Germany ... more >> Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Germany, 30625 Collapse <<

参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.7825 mL
- 13.9123 mL
- 27.8246 mL
- 5 mM
- 0.5565 mL
- 2.7825 mL
- 5.5649 mL
- 10 mM
- 0.2782 mL
- 1.3912 mL
- 2.7825 mL

技术信息

CAS号

93106-60-6

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C19H22FN3O3

运输

蓝冰

分子量

359.39

别名

BAY Vp 2674;PD160788;ENR;Baytril;CFPQ;endrofloxicin;恩诺沙星

溶解度

DMSO	1.0 mg/mL (2.8 mM) warming
Water	Insoluble

动物实验配方

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