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CAS No.: 50679-08-8
Synonyms: (±)-Terfenadine;MDL-991;MDL 9918
Terfenadine is a potent open-channel blocker of hERG with a mean IC50 of 204 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01940393 | Urticaria | Phase 4 | Completed | - | Colombia ... more >> Medellin Medellin, Antioquia, Colombia Collapse << |
NCT02056743 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Clinical Trial Center of Chonbuk National University Hospital Jeonju, Jeollabuk-do, Korea, Republic of Collapse << |
NCT02966665 | Chronic Obstructive Pulmonary ... more >>Disease Pulmonary Artery Hypertension Heart Failure Hypertension Collapse << | Phase 1 | Recruiting | August 2020 | United States, Utah ... more >> George E Wahlen VA Medical Center Recruiting Salt Lake City, Utah, United States, 84132 Contact: Russell Richardson, Ph.D. 801-582-1565 r.richardson@hsc.utah.edu Contact: Ashley Nelson, MD 801-582-1565 ext 4127 ash.nelson@hsc.utah.edu Collapse << |
实验方案
技术信息
CAS号 | 50679-08-8 | 储存条件 |
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分子式 | C32H41NO2 | 运输 | 蓝冰 | |||||||
分子量 | 471.67 | 别名 | (±)-Terfenadine;MDL-991;MDL 9918;NSC 665802;BRN-5857899;Seldane;Terfen;特非那定 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01940393 | Urticaria | Phase 4 | Completed | - | Colombia ... more >> Medellin Medellin, Antioquia, Colombia Collapse << |
NCT02056743 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Clinical Trial Center of Chonbuk National University Hospital Jeonju, Jeollabuk-do, Korea, Republic of Collapse << |
NCT02966665 | Chronic Obstructive Pulmonary ... more >>Disease Pulmonary Artery Hypertension Heart Failure Hypertension Collapse << | Phase 1 | Recruiting | August 2020 | United States, Utah ... more >> George E Wahlen VA Medical Center Recruiting Salt Lake City, Utah, United States, 84132 Contact: Russell Richardson, Ph.D. 801-582-1565 r.richardson@hsc.utah.edu Contact: Ashley Nelson, MD 801-582-1565 ext 4127 ash.nelson@hsc.utah.edu Collapse << |
NCT02391688 | Drug Interaction | Phase 1 | Completed | - | Switzerland ... more >> Centre de Recherche Clinique, HUG, Rue Gabrielle Perret-Gentil 4 Genève, Switzerland, 1211 Collapse << |
NCT00637585 | Allergic Rhinitis | Phase 4 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT02171546 | Healthy | Phase 1 | Terminated | - | - |
NCT01683552 | ITCH | Phase 2 | Completed | - | Italy ... more >> Campus Bio-Medico of Rome University Roma, Italy, 00128 Collapse << |
NCT00783146 | Seasonal Allergic Rhinitis | Phase 4 | Completed | - | - |
NCT02551536 | Allergic Rhinitis | Phase 4 | Completed | - | - |
NCT00783211 | Seasonal Allergic Rhinitis | Phase 4 | Completed | - | - |
NCT03012763 | Pharmacokinetics ... more >> Magnetic Resonance Imaging Administration, Oral Collapse << | Phase 1 | Completed | - | - |
NCT01133470 | Healthy | Phase 1 | Completed | - | India ... more >> Veeda Clinical Research Pvt. Ltd., Ahmedabad, Gujrat, India, 380015 Collapse << |
NCT01586091 | Allergic Rhinitis | Phase 1 | Completed | - | Germany ... more >> University of Berlin Charité Berlin, Germany, 10117 Collapse << |
NCT01306721 | Rhinitis Seasonal | Phase 3 | Completed | - | Japan ... more >> Investigational Site Number 392002 Koganei-Shi, Japan Investigational Site Number 392003 Osaka-Shi, Japan Investigational Site Number 392001 Shinjuku-Ku, Japan Collapse << |
NCT03108274 | Drug Interaction Potentiation | Phase 1 | Completed | - | New Zealand ... more >> Auckland Clinical Studies Auckland, New Zealand, 1150 Collapse << |
NCT02175485 | Rhinitis Allergic | Phase 4 | Completed | - | Japan ... more >> Investigational Site Number 392-001 Shinjuku-ku, Japan Collapse << |
NCT00420082 | Seasonal Allergic Rhinitis | Phase 2 | Completed | - | Austria ... more >> Allergy Center Vienna West Vienna, Austria, A-1150 Collapse << |
NCT01133483 | Healthy | Phase 1 | Completed | - | India ... more >> Veeda Clinical Research Pvt. Ltd., Ahmedabad, Gujrat, India, 380015 Collapse << |
NCT00435461 | Rhinitis, Allergic, Seasonal | Phase 4 | Completed | - | United States, Texas ... more >> GSK Investigational Site Austin, Texas, United States, 78731 GSK Investigational Site Austin, Texas, United States, 78750 GSK Investigational Site Kerrville, Texas, United States, 78028 GSK Investigational Site New Braunfels, Texas, United States, 78130 GSK Investigational Site San Antonio, Texas, United States, 78205 GSK Investigational Site San Antonio, Texas, United States, 78229 Collapse << |
NCT00045955 | Asthma | Phase 3 | Completed | - | United States, New Jersey ... more >> Aventis Pharmaceutical Inc. Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT00502775 | Rhinitis, Allergic, Seasonal | Phase 4 | Completed | - | - |
NCT00636870 | Allergic Rhinitis | Phase 4 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT00502775 | - | - | Completed | - | - |
NCT00637611 | Seasonal Allergic Rhinitis | Phase 4 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT00435461 | - | - | Completed | - | - |
NCT00637455 | Seasonal Allergic Rhinitis | Phase 4 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT00783133 | Seasonal Allergic Rhinitis | Phase 4 | Completed | - | - |
NCT00794768 | Seasonal Allergic Rhinitis | Phase 4 | Completed | - | - |
NCT00794248 | Seasonal Allergic Rhinitis | Phase 4 | Completed | - | - |
NCT00638118 | Allergic Rhinitis | Phase 4 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT01469234 | - | - | Completed | - | - |
NCT01852318 | Uremic Pruritus | Phase 4 | Unknown | May 2015 | Taiwan ... more >> National Taiwan University (NTUH); NTUH Hsin-Chu Branch; NTUH Yun-Lin Branch; Cathay General hospital Not yet recruiting Taipei, Taiwan, 100; 300; 640; 280 Contact: Hsien-Yi Chiu, MD 0972654317 extra.owl0430@yahoo.com.tw Principal Investigator: Hsien-Yi Chiu, MD Collapse << |
NCT01526213 | Food-drug Interaction | Not Applicable | Completed | - | United States, North Carolina ... more >> North Carolina Clinical and Translational Research Center Chapel Hill, North Carolina, United States, 27599 Collapse << |
NCT02908750 | Non Small Cell Lung Cancer | Phase 1 | Active, not recruiting | March 13, 2019 | France ... more >> Research Site Rennes Cedex 9, France, 35033 Korea, Republic of Research Site Seongnam-si, Korea, Republic of, 13620 Research Site Seoul, Korea, Republic of, 05505 Spain Research Site Madrid, Spain, 28040 Research Site Madrid, Spain, 28046 Research Site Madrid, Spain, 28050 Research Site Sevilla, Spain, 41013 Collapse << |
NCT03183297 | Veisalgia | Phase 1 | Not yet recruiting | December 2017 | - |
NCT00044811 | Asthma | Phase 3 | Completed | - | United States, New Jersey ... more >> Aventis Pharmaceuticals Inc. Bridgewater, New Jersey, United States, 08807 Costa Rica Sanofi-Aventis Admnistrative Office Costa Rica, Costa Rica Guatemala Sanofi-Aventis Administrative Office Guatemala City, Guatemala Hungary Sanofi-Aventis Administrative Office Budapest, Hungary Mexico Sanofi-Aventis Administrative Office Mexico, Mexico Poland Sanofi-Aventis Administrative Office Warszawa, Poland Russian Federation Sanofi-Aventis Administrative Office Moscow, Russian Federation Collapse << |
NCT01469234 | Rhinitis | Phase 4 | Completed | - | - |
NCT00044824 | Asthma | Phase 3 | Completed | - | United States, New Jersey ... more >> Aventis Pharmaceuticals Inc. Bridgewater, New Jersey, United States, 08807 Costa Rica Sanofi-Aventis Admnistrative Office Costa Rica, Costa Rica Guatemala Sanofi-Aventis Administrative Office Guatemala City, Guatemala Hungary sanofi-aventis Hungaria Budapest, Hungary Mexico Sanofi-Aventis Administrative Office Mexico, Mexico Poland sanofi-aventis Poland Warszawa, Poland Russian Federation Sanofi-Aventis Aministrative Office Moscow, Russian Federation Collapse << |
NCT01526213 | - | - | Completed | - | - |
NCT00261079 | Pruritus | Phase 4 | Completed | - | Korea, Republic of ... more >> Handok Seoul, Korea, Republic of Collapse << |
NCT00562120 | Allergic Rhinitis | Phase 2 | Completed | - | United States, Nebraska ... more >> Pfizer Investigational Site Omaha, Nebraska, United States, 68131 Collapse << |
NCT00637884 | Cat Induced Allergic Rhinitis | Phase 4 | Completed | - | - |
NCT00562120 | - | - | Completed | - | - |
NCT00649376 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT00647985 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
NCT00547768 | Allergy | Phase 4 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT00741897 | Rhinitis, Allergic, Perennial | Phase 4 | Completed | - | Philippines ... more >> Sanofi-aventis administrative office Makati City, Philippines Collapse << |
NCT00835276 | - | - | Completed | - | - |
NCT00835640 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58102 Collapse << |
NCT01033396 | Allergic Rhinitis | Phase 2 | Completed | - | Canada, Ontario ... more >> Pfizer Investigational Site Kingston, Ontario, Canada, K7L 2V7 Collapse << |
NCT01066754 | Healthy | Phase 1 | Completed | - | Canada ... more >> Anapharm Inc., Sainte-Foy Quebec, Canada, G1V 2K8 Collapse << |
NCT01066767 | Healthy | Phase 1 | Completed | - | Canada ... more >> Anapharm Inc., Sainte-Foy Quebec, Canada, G1V 2K8 Collapse << |
NCT00835276 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58102 Collapse << |
NCT01172522 | - | - | Completed | - | - |
NCT00835640 | - | - | Completed | - | - |
NCT01888718 | Healthy | Phase 1 | Completed | - | India ... more >> Bioserve Clinical Research Private Limited Balanagar, Hyderabad, Andhra Pradesh, India, 500 037 Collapse << |
NCT01767272 | Healthy | Not Applicable | Completed | - | - |
NCT01172522 | Edema | Phase 2 | Completed | - | United States, New Jersey ... more >> TKL Research Paramus, New Jersey, United States, 07652 Collapse << |
NCT01298505 | Healthy | Phase 1 | Terminated(This study was stop... more >>ped due to lack of evidence for clinical efficacy.) Collapse << | - | Singapore ... more >> Pfizer Investigational Site Singapore, Singapore, 188770 Collapse << |
NCT03078777 | Hemodialysis | Phase 4 | Recruiting | August 2020 | Canada, Ontario ... more >> London Health Sciences Centre Recruiting London, Ontario, Canada, N6A5A5 Contact: Brad Urquhart, PhD 5196613756 Brad.Urquhart@schulich.uwo.ca Collapse << |
NCT02157558 | Drug Interactions | Phase 1 | Completed | - | United States, Texas ... more >> Lexicon Investigational Site Dallas, Texas, United States, 75247 Collapse << |
NCT03664882 | Rhinitis Seasonal | Phase 3 | Recruiting | February 2019 | Canada ... more >> Investigational Site Number Recruiting Canada, Canada Collapse << |
NCT00699894 | Postoperative Nausea and Vomit... more >>ing Collapse << | Not Applicable | Withdrawn(Logistical difficult... more >>ies running the study) Collapse << | - | United States, New York ... more >> Long Island Jewish Medical Center/Schneider's Children Hospital New Hyde Park, New York, United States, 11040 Collapse << |
NCT03425097 | Gastroesophageal Reflux | Phase 2 | Recruiting | May 2019 | United States, California ... more >> Silicon Valley Gastroenterology 2490 Hospital Dr. Suite 211 Recruiting Mountain View, California, United States, 94040 Contact: George Triadafilopoulos, MD 650-988-7530 vagt@stanford.edu Collapse << |
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