CAS No.: 1257792-41-8
(Z)-5-(2-Hydroxy-3-(2-(3-methyl-5-oxo-1-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-pyrazol-4(5H)-ylidene)hydrazinyl)phenyl)furan-2-carboxylic acid Catalog No. CSN20592
Synonyms: Hetrombopag
Hetrombopag ethanolamine is a thyroperoxidase (TPO) inhibitor potentially for the treatment of thrombocytopenia and a non-peptide small molecular TPO receptor agonists act as enhancers of stem cells in protecting cardiac myocyte survival from oxidative stress damage.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03603132 Immune Thrombocytopenia Phase 1 Recruiting November 2018 China, Hunan ... more >> The third xiangya hospital Hospital,of central south university Recruiting Changsha, Hunan, China, 410013 Contact: Guoping Yang, PhD Ygp9880@163.com Collapse << NCT03222843 Idiopathic Thrombocytopenic Pu... more >>rpura Collapse << Phase 3 Recruiting December 30, 2020 China, Hubei ... more >> Union Hospital Tongji Medical College Huazhong University of Science and technology Recruiting Wuhan, Hubei, China, 430022 Contact: Yu Hu, Ph.D dr_huyu@126.com Contact: Heng Mei, Ph.D mayheng@126.com China, Sichuan West China Hospital，Sichuan University Not yet recruiting Chengdu, Sichuan, China, 610041 Contact: Ting Niu, MD tingniu@sina.com China, Tianjin Hospital of Blood Diseases, Chinese Academy of Medical Sciences Recruiting Tianjin, Tianjin, China, 300041 Contact: Renchi Yang, MD rcyang65@163.com Collapse << NCT02409394 Healthy Phase 1 Completed - China, Sichuan ... more >> West Hospital, Sichuan University Chengdu, Sichuan, China Collapse << - 更多
- 参考文献
- [1] Zhou N, Wang J, et al. Hetrombopag, a Thrombopoietin Receptor Agonist, Protects Cardiomyocyte Survival from Oxidative Stress Damage as an Enhancer of Stem Cells. Cardiovasc Drugs Ther. 2016 Dec;30(6):567-577.
- [2] Chen T, Chen Z, et al. Development and validation of a LC-MS/MS method for quantification of hetrombopag for pharmacokinetics study. Springerplus. 2015 Oct 29;4:652.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1257792-41-8 | 储存条件 |
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| 分子式 | C25H22N4O5 | 运输 | 蓝冰 | |
| 分子量 | 458.47 | 别名 | Hetrombopag |
