|(S)-N-(丙-2-炔-1-基)-2,3-二氢-1H-茚-1-胺甲磺酸盐|CsnPharm

CAS No.: 202464-88-8

(S)-Rasagiline mesylate/(S)-雷沙吉兰甲磺酸 Catalog No. CSN18085

Synonyms: TVP1022 mesylate;S-PAI mesylate;(S)-Rasagiline Mesylate

TVP1022 mesylate is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.

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技术信息

生物活性

描述TVP1022 mesylate is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00203125	Parkinson's Disease	Phase 3	Completed	-	-
NCT01723228	Parkinson's Disease	Phase 4	Completed	-	-
NCT00104273	Dementia Alzh... more >>eimer's Disease Collapse <<	Phase 2	Completed	-	-

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参考文献

[1] Ertracht O, Liani E, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69.
[2] Berdichevski A, Meiry G, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.7406 mL
- 18.7028 mL
- 37.4056 mL
- 5 mM
- 0.7481 mL
- 3.7406 mL
- 7.4811 mL
- 10 mM
- 0.3741 mL
- 1.8703 mL
- 3.7406 mL

技术信息

CAS号	202464-88-8	储存条件	粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C13H17NO3S	运输	蓝冰
分子量	267.34	别名	TVP1022 mesylate;S-PAI mesylate;(S)-Rasagiline Mesylate;(S)-雷沙吉兰甲磺酸

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT00203125	Parkinson's Disease	Phase 3	Completed	-	-
NCT01723228	Parkinson's Disease	Phase 4	Completed	-	-
NCT00104273	Dementia Alzh... more >>eimer's Disease Collapse <<	Phase 2	Completed	-	-
NCT00256204	Parkinson's Disease	Phase 3	Completed	-	-
NCT00399477	Parkinson's Disease	Phase 4	Completed	-	-
NCT00256204	-	-	Completed	-	-
NCT00936676	-	-	Completed	-	-
NCT01879748	Parkinson's Disease	Phase 1	Completed	-	United States, California ... more >> Teva Investigational Site 10738 Glendale, California, United States Collapse <<
NCT01723228	-	-	Completed	-	-
NCT00203034	Parkinson's Disease	Phase 3	Completed	-	United States, Illinois ... more >> Rush - Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, New York Columbia - Presbyterian Medical Center New York, New York, United States, 10032 University of Rochester Rochester, New York, United States, 14642 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 Collapse <<
NCT01032486	-	-	Completed	-	-
NCT00203060	Parkinson's Disease	Phase 3	Completed	-	-
NCT00203177	Parkinson's Disease	Phase 3	Completed	-	United States, California ... more >> Margolin Brain Institute Fresno, California, United States, 93720 United States, Georgia Emory University Atlanta, Georgia, United States, 30329 United States, Illinois Rush - Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, Nebraska Creighton University Omaha, Nebraska, United States, 68131 United States, New York Long Island Jewish Medical Center New Hyde Park, New York, United States, 11040 University of Rochester Rochester, New York, United States, 14642 United States, Pennsylvania Pennsylvania Hospital Philadelphia, Pennsylvania, United States, 19107 Canada, Quebec CHUM-Hotel-Dieu Montreal, Quebec, Canada, H2w1T8 Collapse <<
NCT00203138	Parkinson's Disease	Phase 3	Completed	-	-
NCT00977665	Multiple System Atrophy	Phase 2	Completed	-	-
NCT00977665	-	-	Completed	-	-
NCT00203164	Parkinson's Disease	Phase 3	Completed	-	United States, California ... more >> Margolin Brain Institute Fresno, California, United States, 93720 United States, Illinois Rush - Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, Nebraska Creighton University Omaha, Nebraska, United States, 68131 United States, New York Long Island Jewish Medical Center New Hyde Park, New York, United States, 11040 University of Rochester Rochester, New York, United States, 14642 United States, Pennsylvania Pennsylvania Hospital Philadelphia, Pennsylvania, United States, 19107 Collapse <<

(S)-Rasagiline mesylate/(S)-雷沙吉兰甲磺酸 Catalog No. CSN18085

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