CAS No.: 53846-50-7
8-异戊烯基柚皮素 Catalog No. CSN14057
Synonyms: Sophoraflavanone B;Flavaprenin;YS04
8-Prenylnaringenin is a phytoestrogen isolated and purified from the herbs of Humulus lupulus with the highest estrogenic activity, shows slight activity in this assay but significant activity by immunostaining, improves mitochondrial function, whereas a high dose of XN (5 µM) worsens the functionality of this organelle, and has more potent effects on promoting osteoblastic bone formation and inhibiting osteoclastic bone resorption by ERα instead of ERβ than the two classic phytoestrogens: genistein and daidzein.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02848430 Food-Drug Interactions Not Applicable Active, not recruiting October 18, 2018 United States, Illinois ... more >> University of Illinois at Chicago Chicago, Illinois, United States, 60612 Collapse << NCT03140397 Safety After Oral Intake ... more >> Pharmacokinetics After Oral Intake Immune Cells Activity Collapse << Early Phase 1 Completed - Germany ... more >> University of Hohenheim Stuttgart, Baden-Württemberg, Germany, 70599 Eberhard Karls University Tuebingen Tübingen, Baden-Württemberg, Germany, 72076 Collapse << - 参考文献
- [1] De Ryck T, Van Impe A, et al. 8-prenylnaringenin and tamoxifen inhibit the shedding of irradiated epithelial cells and increase the latency period of radiation-induced oral mucositis : cell culture and murine model. Strahlenther Onkol. 2015 May;191(5):429-36.
- [2] Urmann C, Oberbauer E, et al. Neurodifferentiating potential of 8-prenylnaringenin and related compounds in neural precursor cells and correlation with estrogen-like activity. Planta Med. 2015 Mar;81(4):305-11.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 53846-50-7 | 储存条件 |
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| 分子式 | C20H20O5 | 运输 | 蓝冰 | |
| 分子量 | 340.37 | 别名 | Sophoraflavanone B;Flavaprenin;YS04;8-异戊烯基柚皮素 |
