CAS No.: 5302-45-4
三七素 Catalog No. CSN13605
Synonyms: Dencichin;ODAP;β-ODAP
β-ODAP is an analog of glutamic acid present in Lathyrus sativus (grass pea) that activates AMPA receptors.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Eslavath RK, Sharma D, et al. β-N-oxalyl-L-α, β- diaminopropionic acid induces HRE expression by inhibiting HIF-prolyl hydroxylase-2 in normoxic conditions. Eur J Pharmacol. 2016 Nov 15;791:405-411.
- [2] Jammulamadaka N, Burgula S, et al. β-N-oxalyl-L-α,β-diaminopropionic acid regulates mitogen-activated protein kinase signaling by down-regulation of phosphatidylethanolamine-binding protein 1. J Neurochem. 2011 Jul;118(2):176-86.
- [3] Lin CY, Lynch G, Gall CM. AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling. J Neurochem. 2005 Jul;94(2):531-46
- [4] Kusama-Eguchi K, Ikegami F, Kusama T, Lambein F, Watanabe K. Effects of β-ODAP and its biosynthetic precursor on the electrophysiological activity of cloned glutamate receptors. Environ Toxicol Pharmacol. 1996 Dec 20;2(4):339-42
- [5] Kusama-Eguchi K, Miyano T, Yamamoto M, Suda A, Ito Y, Ishige K, Ishii M, Ogawa Y, Watanabe K, Ikegami F, Kusama T. New insights into the mechanism of neurolathyrism: L-β-ODAP triggers [Ca2+]i accumulation and cell death in primary motor neurons through transient receptor potential channels and metabotropic glutamate receptors. Food Chem Toxicol. 2014 May;67:113-22
- [6] Jiao CJ, Jiang JL, Ke LM, Cheng W, Li FM, Li ZX, Wang CY. Factors affecting β-ODAP content in Lathyrus sativus and their possible physiological mechanisms. Food Chem Toxicol. 2011 Mar;49(3):543-9
- [7] Xiong JL, Bai X, Batool A, Kong HY, Tan RY, Wang YF, Li ZX, Xiong YC. [Ecological function and application of toxin beta-ODAP in grass pea (Lathyrus sativus)]. Ying Yong Sheng Tai Xue Bao. 2014 Apr;25(4):1197-205. Chinese
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 5302-45-4 | 储存条件 |
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| 分子式 | C5H8N2O5 | 运输 | 蓝冰 | |
| 分子量 | 176.13 | 别名 | Dencichin;ODAP;β-ODAP;BRN-2259036;Ox-Dapro;三七素 |
