CAS No.: 1200-22-2
硫辛酸 Catalog No. CSN12507
Synonyms: (R)-(+)-α-Lipoic acid;R-(+)-Thioctic acid;(R)-(+)-alpha-Lipoic Acid
Lipoic Acid can inhibit TNF-alpha-induced NF-kappaB activation.
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批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01902381 Previously Treated Myelodyspla... more >>stic Syndromes Collapse << Phase 2 Suspended(Lack of accrual) November 2018 United States, North Carolina ... more >> Comprehensive Cancer Center of Wake Forest University Winston-Salem, North Carolina, United States, 27157 Collapse << NCT01839981 Acinar Cell Adenocarcinoma of ... more >>the Pancreas Duct Cell Adenocarcinoma of the Pancreas Recurrent Pancreatic Cancer Stage III Pancreatic Cancer Stage IV Pancreatic Cancer Collapse << Phase 1 Completed - United States, North Carolina ... more >> Comprehensive Cancer Center of Wake Forest University Winston-Salem, North Carolina, United States, 27157 Collapse << NCT01471652 Chronic Fatigue Syndrome Phase 2 Withdrawn(PI left the institut... more >>ion) Collapse << - United States, New York ... more >> Columbia University Department of Clinical Genetics New York, New York, United States, 10032 Collapse << - 更多
- 参考文献
- [1] Petronilho F, Florentino D, et al. Alpha-Lipoic Acid Attenuates Oxidative Damage in Organs After Sepsis. Inflammation. 2016 Feb;39(1):357-365.
- [2] Lee HA, Hughes DA. Alpha-lipoic acid modulates NF-kappaB activity in human monocytic cells by direct interaction with DNA. Exp Gerontol. 2002 Jan-Mar;37(2-3):401-10.
- [3] Li BJ, Hao XY, Ren GH, Gong Y. Effect of lipoic acid combined with paclitaxel on breast cancer cells. Genet Mol Res. 2015 Dec 22;14(4):17934-40
- [4] Zhao H, Bu M, Li B, Zhang Y. Lipoic acid inhibited desflurane-induced hippocampal neuronal apoptosis through Caspase3 and NF-KappaB dependent pathway. Tissue Cell. 2018 Feb;50:37-42
- [5] Van Nguyen T, Piao CH, Fan YJ, Shin DU, Kim SY, Song HJ, Song CH, Shin HS, Chai OH. Anti-allergic rhinitis activity of α-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling. Sci Rep. 2020 Jul 27;10(1):12528
- [6] Fratantonio D, Speciale A, Molonia MS, Bashllari R, Palumbo M, Saija A, Cimino F, Monastra G, Virgili F. Alpha-lipoic acid, but not di-hydrolipoic acid, activates Nrf2 response in primary human umbilical-vein endothelial cells and protects against TNF-α induced endothelium dysfunction. Arch Biochem Biophys. 2018 Oct 1;655:18-25
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1200-22-2 | 储存条件 |
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| 分子式 | C8H14O2S2 | 运输 | 蓝冰 | |||
| 分子量 | 206.33 | 别名 | (R)-(+)-α-Lipoic acid;R-(+)-Thioctic acid;(R)-(+)-alpha-Lipoic Acid;alpha-Lipoic Acid;(R)-α-Lipoic Acid;(R)-(+)-Lipoic Acid;Lipoic Acid;(R)-5-(1,2-Dithiolan-3-yl)pentanoic acid;Lipoate;Verla-Lipon;Thioctacide T;Thioctic Acid;Thiogamma Injekt;Thiogamma oral;硫辛酸 | |||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT01902381 | Previously Treated Myelodyspla... more >>stic Syndromes Collapse << | Phase 2 | Suspended(Lack of accrual) | November 2018 | United States, North Carolina ... more >> Comprehensive Cancer Center of Wake Forest University Winston-Salem, North Carolina, United States, 27157 Collapse << |
| NCT01839981 | Acinar Cell Adenocarcinoma of ... more >>the Pancreas Duct Cell Adenocarcinoma of the Pancreas Recurrent Pancreatic Cancer Stage III Pancreatic Cancer Stage IV Pancreatic Cancer Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> Comprehensive Cancer Center of Wake Forest University Winston-Salem, North Carolina, United States, 27157 Collapse << |
| NCT01471652 | Chronic Fatigue Syndrome | Phase 2 | Withdrawn(PI left the institut... more >>ion) Collapse << | - | United States, New York ... more >> Columbia University Department of Clinical Genetics New York, New York, United States, 10032 Collapse << |
| NCT02696512 | Brain Injury | Phase 1 Phase 2 | Unknown | April 2017 | United States, New Jersey ... more >> International Brain Research Foundation Recruiting Edison, New Jersey, United States, 08837 Contact: Philip Defina, PhD 732-494-7600 pdefina@ibrfinc.org Principal Investigator: Philip Defina, PhD Collapse << |
| NCT03177122 | Sterility Inf... more >>ertility Collapse << | Phase 4 | Recruiting | July 2019 | Lebanon ... more >> American University of Beirut Medical Center Recruiting Beirut, Lebanon Contact: Johnny Awwad, MD 00961 1 350000 ext 5606 jawwad@aub.edu.lb Collapse << |
| NCT02115724 | Cardiovascular Disease | Not Applicable | Recruiting | April 2020 | United States, Georgia ... more >> Georgia Prevention Institute , Georgia Regents University Recruiting Augusta, Georgia, United States, 30912 Contact: Ryan Harris, PhD 706-721-5998 ryharris@gru.edu Contact: Jacob Looney, BS 706 721-5483 jlooney@gru.edu Principal Investigator: Ryan Harris, PhD Collapse << |
| NCT01398943 | Pulmonary Disease, Chronic Obs... more >>tructive Collapse << | Not Applicable | Completed | - | United States, Georgia ... more >> Augusta University Augusta, Georgia, United States, 30912 Collapse << |
| NCT00664001 | Acute Mountain Sickness | Phase 3 | Completed | - | United Kingdom ... more >> University of Edinburgh Edinburgh, United Kingdom Collapse << |
| NCT02392767 | Endothelial Dysfunction ... more >> Hyperhomocysteinemia Hypertension Grade I, Subgroup "Borderline" (WHO) Collapse << | Not Applicable | Completed | - | Germany ... more >> BioTeSys Esslingen, Germany, 73728 Collapse << |
| NCT02774226 | Chronic Obstructive Pulmonary ... more >>Disease (COPD) Collapse << | Phase 2 | Recruiting | September 2018 | United States, Georgia ... more >> Georgia Prevention Institute Recruiting Augusta, Georgia, United States, 30912 Contact: Ryan Harris, Ph.D. 706-721-5998 ryharris@augusta.edu Contact: Nichole Seigler, BA 706-721-5998 maseigler@augusta.edu Collapse << |
| NCT01398943 | - | - | Completed | - | - |
| NCT02392767 | - | - | Completed | - | - |
| NCT00122447 | - | - | Completed | - | - |
| NCT02690064 | Cystic Fibrosis | Not Applicable | Recruiting | December 2018 | United States, Georgia ... more >> Georgia Prevention Institute Recruiting Augusta, Georgia, United States, 30912 Contact: Ryan Harris, Ph.D. 706-721-5998 ryharris@gru.edu Contact: Nichole Seigler, BA 706-721-5998 maseigler@gru.edu Collapse << |
| NCT01398423 | Hypertension ... more >>Diabetes Mellitus, Type 2 Collapse << | Phase 2 | Completed | - | United States, California ... more >> Garden Grove, California, United States, 92844 La Mesa, California, United States, 91942 Northridge, California, United States, 91324 Riverside, California, United States, 92505 Tustin, California, United States, 92780 United States, Florida Kissimmee, Florida, United States, 34741 Miami, Florida, United States, 33015 United States, Georgia Macon, Georgia, United States, 31217 Tucker, Georgia, United States, 30084 United States, Maryland Reisterstown, Maryland, United States, 21136 United States, Minnesota Brooklyn Center, Minnesota, United States, 55430 United States, North Carolina Cary, North Carolina, United States, 27511 Greenville, North Carolina, United States, 27834 New Bern, North Carolina, United States, 28562 Raleigh, North Carolina, United States, 27610 United States, South Carolina Aiken, South Carolina, United States, 29801 United States, Texas San Antonio, Texas, United States, 78215 San Antonio, Texas, United States, 78228 United States, Virginia Norfolk, Virginia, United States, 23507 Collapse << |
| NCT02348125 | Autism Spectrum Disorders ... more >> Mitochondrial Diseases Collapse << | Phase 1 | Recruiting | June 2017 | United States, Pennsylvania ... more >> St. Christopher's Hospital for Children Recruiting Philadelphia, Pennsylvania, United States, 19134 Contact: Michael J Goldenthal, PhD 215-427-6786 michael.goldenthal@drexelmed.edu Collapse << |
| NCT00122447 | Impaired Glucose Tolerance ... more >> Prediabetic State Collapse << | Not Applicable | Completed | - | United States, Georgia ... more >> Grady Health System Atlanta, Georgia, United States, 30303 Emory University Hospital Atlanta, Georgia, United States, 30322 Collapse << |
| NCT01224353 | Diabetics | Phase 2 Phase 3 | Unknown | July 2011 | China, Jiangsu ... more >> Jiangsu Provincial People's Hospital Not yet recruiting Nanjing, Jiangsu, China, 210029 Contact: Qi Wan 86 13770316989 qi_wan@126.com Sub-Investigator: Jie Gong Sub-Investigator: Wei Wang Principal Investigator: Qi Wan Sub-Investigator: Ping Gu Affiliated Hospital of Nantong University Not yet recruiting Nantong, Jiangsu, China, 226001 Contact: Kaifu Ke 0513-85052569 kekaifu_nt@126.com Sub-Investigator: Maohong Cao Principal Investigator: Kaifu Ke Sub-Investigator: Aihong Li The Second Affiliated Hospital of Soochow University Not yet recruiting Suzhou, Jiangsu, China, 215004 Contact: Heqing Zhao 86 13004571960 zhao_heqing@163.com Principal Investigator: Heqing Zhao Sub-Investigator: Xia Zhang Sub-Investigator: Weidong Hu The First Affiliated Hospital of Soochow University Not yet recruiting Suzhou, Jiangsu, China, 215006 Contact: Wanli Dong 86 512 65223637 ext 8317 dwlsz@163.com Principal Investigator: Wanli Dong Sub-Investigator: Shouru Xue Sub-Investigator: Xiaowei Hu Sub-Investigator: Hongxia Wang Wuxi No.2 People's Hospital Not yet recruiting Wuxi, Jiangsu, China, 214002 Contact: Yuenan Kong 86 051267727501 ext 3503 kkyynn2008@yahoo.cn Principal Investigator: Yuenan Kong Sub-Investigator: Wenzhuo Dai Sub-Investigator: Tao Ma Collapse << |
| NCT01177189 | Aging | Not Applicable | Terminated(Inadequate effect s... more >>ize.) Collapse << | - | - |
| NCT00948324 | Type 2 Diabetes Mellitus | Phase 4 | Suspended | December 2021 | - |
| NCT03629613 | Cardiovascular Diseases | Not Applicable | Not yet recruiting | August 1, 2019 | - |
| NCT00237718 | End-stage Renal Disease | Phase 2 | Completed | - | United States, Tennessee ... more >> Fresenius Medical Care North America Nashville, Tennessee, United States, 37215 Collapse << |
| NCT00117403 | Alzheimer's Disease | Phase 1 | Completed | - | United States, Arizona ... more >> University of Arizona Tucson, Arizona, United States, 85724 United States, California University of California- Irvine Irvine, California, United States, 92697 University of California, San Diego La Jolla, California, United States, 92037 University of California, Los Angeles Los Angeles, California, United States, 90095 United States, Florida Wien Center, Mount Sinai Medical Center Miami Beach, Florida, United States, 33140 United States, Kentucky University of Kentucky Lexington, Kentucky, United States, 40536 United States, New Jersey University of Medicine and Dentistry of New Jersey Piscataway, New Jersey, United States, 08855 United States, New York Neurological Care of CNY Syracuse, New York, United States, 13210 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44120 United States, Oregon Oregon Health Sciences University Portland, Oregon, United States, 97239 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, South Carolina Medical University of South Carolina North Charleston, South Carolina, United States, 29406 United States, Washington University of Washington Seattle, Washington, United States, 98108 Collapse << |
| NCT01872351 | - | - | Withdrawn(PI left the institut... more >>ion) Collapse << | - | United States, New York ... more >> Columbia University Medical Center New York, New York, United States, 10032 Collapse << |
| NCT00237718 | - | - | Completed | - | - |
| NCT02157207 | Healthy | Not Applicable | Completed | - | United States, Illinois ... more >> University of Illinois - Chicago Chicago, Illinois, United States, 60612 Collapse << |
| NCT01054768 | Anemia, Sickle Cell | Phase 2 | Completed | - | United States, California ... more >> Children's Hospital & Research Center Oakland Oakland, California, United States, 94609 Collapse << |
| NCT00004770 | Mitochondrial Myopathy | Not Applicable | Completed | - | - |
| NCT01495260 | Adrenomyeloneuropathy | Phase 2 | Completed | - | Spain ... more >> Hospital Universitari de Bellvitge L'Hospitalet de LLobregat, Barcelona, Spain, 08907 Collapse << |
| NCT00719706 | Bipolar Depression | Phase 2 | Completed | - | United States, Massachusetts ... more >> McLean Hospital Belmont, Massachusetts, United States, 02478 Collapse << |
| NCT00002154 | Cognitive Disorders ... more >> HIV Infections Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> Johns Hopkins Hosp Baltimore, Maryland, United States, 212876965 United States, New York Columbia Univ New York, New York, United States, 10032 Univ of Rochester Med Ctr Rochester, New York, United States, 14642 Collapse << |
| NCT00719706 | - | - | Completed | - | - |
| NCT01895699 | Contrast Agent ... more >> Endothelial Function Cytokines Apoptosis of Endothelial Progenitor Cell Free Radical Alpha-lipoic Acid Collapse << | Phase 4 | Completed | - | China, Hubei ... more >> Wuhan General Hospital Wuhan, Hubei, China, 430070 Collapse << |
| NCT00308971 | Chronic Kidney Disease | Phase 2 | Completed | - | United States, Maine ... more >> Maine Medical Center Portland, Maine, United States, 04102 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
| NCT02971878 | Culture Media ... more >> Blastocyst Antioxidants Embryo Human Collapse << | Not Applicable | Completed | - | Sweden ... more >> Fertilitetscentrum Gothenburg, Box 5418, Sweden, 40229 Collapse << |
| NCT00328601 | Diabetic Polyneuropathy | Phase 3 | Completed | - | Israel ... more >> Wolfson Medical Center, Diabetes Unit Holon, Israel, 58100 Haddassah Medical Center Ein Kerem, Diabetes Unit Jerusalem, Israel, 91120 Russian Federation Chair of Nervous Diseases of IM Sechenov Moscow Medical Academy at City Clinical Hospital Moscow, Russian Federation, 119048 Chair of Endocrinology and Diabetology of Russian Medical Academy of Postgraduate Education at Central Clinical Hospital of Ministry of Communication RF Moscow, Russian Federation, 125315 Federal Centre of Medical Social Expertise and Rehabilitation of Invalids, Centre Diabetic Food Moscow, Russian Federation, 127486 Collapse << |
| NCT02775266 | Diabetes Mellitus ... more >> Periodontitis Collapse << | Not Applicable | Completed | - | India ... more >> Mohans Diabetic Centre Hyderabad, Telangana, India, 500029 Collapse << |
| NCT00703989 | Type 1 Diabetes | Not Applicable | Completed | - | United States, New York ... more >> GCRC, Albert Einstein College of Medicine Bronx, New York, United States, 10461 Collapse << |
| NCT00387543 | - | - | Completed | - | United States, Minnesota ... more >> Mayo Clinic Rochester, Minnesota, United States, 55905 Collapse << |
| NCT00977483 | Diabetic Polyneuropathy | Phase 3 | Completed | - | - |
| NCT01524861 | Apical Ballooning Syndrome ... more >> Nervous System Diseases, Sympathetic Collapse << | Phase 4 | Completed | - | Italy ... more >> Dept Geriatric and Metabolic diseases SUN Naples, Italy Collapse << |
| NCT01261143 | Diabetic Neuropathies | Phase 3 | Completed | - | Korea, Republic of ... more >> Kyung soo Ko Seoul, Korea, Republic of Collapse << |
| NCT01696448 | Metabolic Syndrome | Not Applicable | Completed | - | United States, Georgia ... more >> Atlanta Vascular Research Foundation Atlanta, Georgia, United States, 30342 Collapse << |
| NCT02016495 | Pregnancy | Phase 4 | Completed | - | Italy ... more >> Clinica Villa delle Querce Naples, Italy Collapse << |
| NCT00033176 | Acquired Immunodeficiency Synd... more >>rome HIV Infections Collapse << | Phase 2 | Completed | - | United States, California ... more >> Quest Clinical Research San Francisco, California, United States, 94115 Eye Clinic, Santa Clara Valley Medical Center San Jose, California, United States, 95128 Collapse << |
| NCT00187564 | Diabetes Mellitus, Type 1 | Not Applicable | Completed | - | United States, California ... more >> UCSF Division of Pediatric Endocrinology San Francisco, California, United States, 94143-0434 Collapse << |
| NCT03023514 | Women Infertility | Phase 4 | Completed | - | Greece ... more >> Iakentro Advanced Medical Centre, IVF Unit Thessaloniki, Greece Collapse << |
| NCT01808300 | Healthy | Phase 1 | Completed | - | - |
| NCT00490867 | Type 2 Diabetes | Phase 2 | Completed | - | - |
| NCT00505427 | Insulin Resistance ... more >> Oxidative Stress Collapse << | Phase 1 | Completed | - | United States, California ... more >> University of California at San Francisco San Francisco, California, United States, 94143 Collapse << |
| NCT00477607 | Ototoxicity U... more >>nspecified Adult Solid Tumor Collapse << | Phase 2 Phase 3 | Completed | - | United States, Oregon ... more >> VA Medical Center, Portland Portland, Oregon, United States, 97201 Oregon Health & Science University Portland, Oregon, United States, 97239 Collapse << |
| NCT00079807 | HIV Periphera... more >>l Neuropathy Collapse << | Phase 1 Phase 2 | Completed | - | United States, North Carolina ... more >> University of North Carolina Chapel Hill Chapel Hill, North Carolina, United States, 27599-7025 Collapse << |
| NCT00065624 | Hypercholesterolemia | Phase 2 | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
| NCT01650181 | Liver Disease | Phase 4 | Completed | - | Mexico ... more >> Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Mexico City, Mexico, 14000 Collapse << |
| NCT00477607 | - | - | Completed | - | - |
| NCT02601898 | Subchorionic Hematoma in the F... more >>irst Trimester Pregnancy Miscarriage Collapse << | Phase 4 | Completed | - | Italy ... more >> Azienda USL Ferrara Ferrara, Italy Collapse << |
| NCT01208948 | Diabetes Mellitus ... more >> Macular Edema Collapse << | Phase 3 | Completed | - | Germany ... more >> Department of Ophthalmology Munich, Germany, 80336 Collapse << |
| NCT00676156 | Multiple Sclerosis | Phase 1 | Completed | - | United States, Oregon ... more >> Oregon Health and Science University Multiple Sclerosis Dept. Portland, Oregon, United States, 97239 Collapse << |
| NCT00845156 | Insulin Resistance | Not Applicable | Completed | - | United States, California ... more >> University of California at San Francisco San Francisco, California, United States, 94143 Collapse << |
| NCT01138774 | Obesity Body ... more >>Fat Insulin Resistance Collapse << | Not Applicable | Completed | - | Spain ... more >> Department of Nutrition, Food Science, Physiology and Toxicology. University of Navarra Pamplona, Navarra, Spain, 31008 Collapse << |
| NCT01984567 | Oxidative Stress | Not Applicable | Unknown | January 2014 | Netherlands ... more >> Maastricht University Medical Centre Maastricht, Limburg, Netherlands, 6229 ER Collapse << |
| NCT00090402 | - | - | Completed | - | - |
| NCT01537549 | Progressive Supranuclear Palsy | Phase 1 Phase 2 | Completed | - | United States, New York ... more >> Weill Cornell Medical College New York, New York, United States, 10021 Collapse << |
| NCT03428139 | Radicular; Neuropathic, Lumbar... more >>, Lumbosacral Collapse << | Phase 2 | Completed | - | Egypt ... more >> Assiut university faculty of medicine Assiut, Egypt, 7111 Collapse << |
| NCT00112996 | Neurotoxicity ... more >> Unspecified Adult Solid Tumor, Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific Collapse << | Phase 3 | Completed | - | United States, Arkansas ... more >> Hembree Mercy Cancer Center at St. Edward Mercy Medical Center Fort Smith, Arkansas, United States, 72913 United States, Indiana Horizon Oncology Center Lafayette, Indiana, United States, 47905 United States, Kansas CCOP - Wichita Wichita, Kansas, United States, 67214-3882 United States, Louisiana Cabrini Center for Cancer Care at Christus St. Frances Cabrini Hospital Alexandria, Louisiana, United States, 71301 United States, Michigan CCOP - Kalamazoo Kalamazoo, Michigan, United States, 49007-3731 United States, Minnesota CCOP - Metro-Minnesota St. Louis Park, Minnesota, United States, 55416 United States, Missouri Cancer Research for the Ozarks Springfield, Missouri, United States, 65804 United States, Oregon CCOP - Columbia River Oncology Program Portland, Oregon, United States, 97225 United States, Pennsylvania CCOP - Main Line Health Wynnewood, Pennsylvania, United States, 19096 United States, South Carolina CCOP - Greenville Greenville, South Carolina, United States, 29615 United States, Texas University of Texas M.D. Anderson CCOP Research Base Houston, Texas, United States, 77030-4009 CCOP - Scott and White Hospital Temple, Texas, United States, 76508 United States, Wisconsin Marshfield Clinic - Marshfield Center Marshfield, Wisconsin, United States, 54449 Collapse << |
| NCT01537549 | - | - | Completed | - | - |
| NCT00090402 | Alzheimer's Disease ... more >> Oxidative Stress Dementia Hyperlipidemia Inflammation Collapse << | Phase 1 Phase 2 | Completed | - | United States, Oregon ... more >> Oregon Health and Science University Portland, Oregon, United States, 97239 Collapse << |
| NCT00857376 | Metabolic Syndrome | Phase 2 | Completed | - | - |
| NCT03491969 | Ischemic Heart Failure | Phase 4 | Not yet recruiting | April 30, 2022 | - |
| NCT02651636 | Polycystic Ovary Syndrome ... more >> Menstrual Pattern Hyperandrogenism Metabolic Features Collapse << | Not Applicable | Completed | - | - |
| NCT00997438 | Multiple Sclerosis | Phase 1 | Completed | - | United States, Oregon ... more >> Oregon Health & Science University Portland, Oregon, United States, 97239 Portland VA Medical Center Portland, Oregon, United States, 97239 Collapse << |
| NCT02382328 | Carpal Tunnel Syndrome | Phase 2 | Completed | - | Mexico ... more >> Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde Guadalajara, Jalisco, Mexico, 44280 Collapse << |
| NCT00997438 | - | - | Completed | - | - |
| NCT01888861 | Oxidative Stress ... more >> Inflammation Malnutrition Collapse << | Phase 3 | Unknown | September 2013 | Iran, Islamic Republic of ... more >> Shiraz University of Medical Sciences, Department of Nutrition Recruiting Shiraz, Fars, Iran, Islamic Republic of, 7157617516 Contact: Najmeh Hejazi, PhD n20hejazi@yahoo.com Principal Investigator: Najmeh Hejazi, PhD Collapse << |
| NCT02666170 | Polycystic Ovary Syndrome | Not Applicable | Unknown | - | - |
| NCT01396733 | Thyroid Cance... more >>r Collapse << | Phase 2 | Unknown | December 2013 | Korea, Republic of ... more >> Asan Medical Center Recruiting Seoul, Korea, Republic of, 138-736 Contact: Tae Yong Kim, MD, PhD 82-2-3010-3249 tykim@amc.seoul.kr Principal Investigator: Won Bae Kim, MD, PhD Collapse << |
| NCT02910531 | Cystinuria | Phase 2 | Recruiting | December 2022 | United States, California ... more >> University of California, San Francisco Recruiting San Francisco, California, United States, 94143 Collapse << |
| NCT01895621 | Entrapment Neuropathy, Carpal ... more >>Tunnel Compression Neuropathy, Carpal Tunnel Median Neuropathy, Carpal Tunnel Collapse << | Phase 4 | Completed | - | Italy ... more >> Istituto Ortopedico Rizzoli Bologna, Italy, 40136 Collapse << |
| NCT03062163 | Lipolysis | Not Applicable | Completed | - | Thailand ... more >> Faculty of Medicine, Chulalongkorn University Bangkok, Thailand, 10330 Collapse << |
| NCT01313117 | Peripheral Neuropathy | Phase 1 Phase 2 | Completed | - | United States, Illinois ... more >> Northwestern Medical Faculty Foundation Chicago, Illinois, United States, 60611 Collapse << |
| NCT00764270 | Atherosclerosis | Phase 2 Phase 3 | Active, not recruiting | December 2018 | United States, Oregon ... more >> Oregon Health & Science University Portland, Oregon, United States, 97201 Collapse << |
| NCT00994513 | Obesity Cardi... more >>ovascular Disease Type 2 Diabetes Collapse << | Phase 2 Phase 3 | Completed | - | China, Xinjiang ... more >> Xinjiang Medical University Urumqi, Xinjiang, China, 830054 Collapse << |
| NCT00795262 | Diabetes Hype... more >>rtension Collapse << | Not Applicable | Completed | - | United States, Georgia ... more >> Atlanta Vascular Research Foundation Tucker, Georgia, United States, 30084 Collapse << |
| NCT01355952 | Obesity Weigh... more >>t Loss Schizophrenia Collapse << | Not Applicable | Completed | - | United States, Connecticut ... more >> Connecticut Mental Health Center New Haven, Connecticut, United States, 06519 Collapse << |
| NCT01313117 | - | - | Completed | - | - |
| NCT01880372 | Moderate Non-proliferative Dia... more >>betic Retinopathy Collapse << | Phase 1 Phase 2 | Suspended(Low number of patien... more >>ts enrolled) Collapse << | January 2017 | United States, Michigan ... more >> Ferris State University Big Rapids, Michigan, United States, 49307 Retina Specialists of Michigan Grand Rapids, Michigan, United States, 49525 Collapse << |
| NCT01780974 | - | - | Completed | - | - |
| NCT01406704 | NASH (Non-alcoholic Steato-hep... more >>atitis) Collapse << | Phase 4 | Terminated(because of withdraw... more >>al of Avandia sale due to its risks outweigh its benefits) Collapse << | December 2013 | - |
| NCT01978405 | Acute Kidney Injury ... more >> The Changes of Plasma Creatinine The Changes of Plasma Free Radicals The Changes of Endothelium-dependent Arterial Dilation Collapse << | Phase 4 | Unknown | June 2014 | China, Hubei ... more >> Wuhan General Hospital Recruiting Wuhan, Hubei, China, 430070 Contact: Xiang Guangda, MD +8602768878410 Collapse << |
| NCT00398892 | Diabetes Mellitus, Type 2 | Phase 2 | Unknown | January 2011 | United Kingdom ... more >> Diabetes Department, St John's Hospital Recruiting Livingston, Scotland, United Kingdom, EH54 6PP Principal Investigator: James D Walker, MD Collapse << |
| NCT00765310 | Atherosclerosis | Phase 2 Phase 3 | Active, not recruiting | December 2018 | United States, Oregon ... more >> Oregon Health & Science University Portland, Oregon, United States, 97201 Collapse << |
| NCT03612037 | PreDiabetes | Not Applicable | Active, not recruiting | December 30, 2018 | - |
| NCT03257514 | Cesarean Section; Dehiscence ... more >> Cesarean Scar Niche Collapse << | Phase 2 | Completed | - | Egypt ... more >> Ain Shams University Maternity Hospital Cairo, Abbassia, Egypt, 02002 Collapse << |
| NCT01221350 | Asthma Allerg... more >>ic Rhinitis Collapse << | Not Applicable | Completed | - | Mexico ... more >> Hospital Civil de Guadalajara "Juan I. Menchaca" Guadalajara, Jalisco, Mexico, 44340 Departamento de Fisiología, CUCS, UdeG Guadalajara, Jalisco, Mexico, 44348 Collapse << |
| NCT01780974 | Treated Hypertension | Phase 1 Phase 2 | Completed | - | United States, Oregon ... more >> Lynne Shinto, ND, MPH Portland, Oregon, United States, 97239 Oregon Health & Science University Portland, Oregon, United States, 97239 Collapse << |
| NCT02937363 | G6PD Deficiency | Not Applicable | Completed | - | Greece ... more >> Department of Physical Education & Sport Science of the University of Thessaly Trikala, Karyes, Greece, 42100 Collapse << |
| NCT01221350 | - | - | Completed | - | - |
| NCT01188811 | - | - | Completed | - | - |
| NCT01188811 | Multiple Sclerosis, Chronic Pr... more >>ogressive Collapse << | Phase 2 Phase 3 | Completed | - | United States, Oregon ... more >> VA Portland Health Care System, Portland, OR Portland, Oregon, United States, 97239 Collapse << |
| NCT00962429 | CIDP Chronic ... more >>Inflammatory Demyelinating Polyneuropathy Collapse << | Phase 2 | Completed | - | United States, Oregon ... more >> Oregon Health & Science University Portland, Oregon, United States, 97239 Collapse << |
| NCT01294176 | Optic Neuritis | Phase 1 | Unknown | October 2015 | United States, Oregon ... more >> Oregon Health & Science University Recruiting Portland, Oregon, United States, 97239 Principal Investigator: Vijayshree Yadav, MBBS, MCR Collapse << |
| NCT01058941 | Alzheimer's Disease | Phase 1 Phase 2 | Completed | - | United States, Oregon ... more >> Oregon Health & Science University Portland, Oregon, United States, 97239 Collapse << |
| NCT01058941 | - | - | Completed | - | - |
| NCT02133664 | Multiple Sclerosis ... more >> Cognition Collapse << | Phase 1 Phase 2 | Completed | - | United States, Oregon ... more >> Oregon Health and Science University Portland, Oregon, United States, 97239 Collapse << |
| NCT02133664 | - | - | Completed | - | - |
| NCT01877590 | Type 2 Diabetes ... more >> Coronary Artery Disease Left Ventricular Mass Collapse << | Phase 4 | Completed | - | China, Hubei ... more >> Wuhan General Hospital Wuhan, Hubei, China, 430070 Collapse << |
| NCT02439879 | Diabetic Neuropathy | Phase 4 | Completed | - | - |
| NCT01056497 | Type 2 Diabetes ... more >> Prediabetes Collapse << | Phase 4 | Completed | - | Canada, Ontario ... more >> Toronto General Hospital Toronto, Ontario, Canada, M5G 2C4 Collapse << |
| NCT02439879 | - | - | Completed | - | - |
| NCT03342599 | Metabolic Syndrome ... more >> Obesity Collapse << | Not Applicable | Completed | - | United States, California ... more >> University of La Verne Kinesiology Laboratory La Verne, California, United States, 91750 Collapse << |
| NCT02760823 | Toxicity | Phase 2 | Unknown | January 2018 | - |
| NCT03493841 | Multiple Sclerosis ... more >> Progressive Multiple Sclerosis Secondary Progressive Multiple Sclerosis Primary Progressive Multiple Sclerosis Collapse << | Phase 1 | Recruiting | September 1, 2019 | United States, Oregon ... more >> Oregon Health & Science University Recruiting Portland, Oregon, United States, 97239 Contact: Cassidy Taylor taylocas@ohsu.edu Principal Investigator: Michelle Cameron Collapse << |
| NCT03589690 | Metabolic Syndrome | Not Applicable | Not yet recruiting | July 25, 2019 | - |
| NCT02613572 | Age-Related Macular Degenerati... more >>on Collapse << | Phase 1 Phase 2 | Active, not recruiting | June 2019 | United States, Iowa ... more >> University of Iowa Hospitals and Clinics, Department of Ophthalmology & Visual Sciences Iowa City, Iowa, United States, 52242 United States, New Jersey NJ Retina Teaneck, New Jersey, United States, 07666 United States, Oregon Oregon Regina. LLP Eugene, Oregon, United States, 97401 Retina Northwest, P.C. Portland, Oregon, United States, 97210 United States, Pennsylvania Scheie Eye Institute of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT03161028 | Multiple Sclerosis | Phase 2 | Recruiting | April 1, 2021 | United States, Alabama ... more >> University of Alabama at Birmingham Not yet recruiting Birmingham, Alabama, United States, 35294 Contact: Kerry Howard 205-934-1885 kdhoward@uabmc.edu Contact: John Rinker II, MD jrinker@uabmc.edu United States, District of Columbia Washington DC VA Medical Center, Washington, DC Not yet recruiting Washington, District of Columbia, United States, 20422 Contact: Heidi Maloni, PhD 202-745-8000 ext 57873 Heidi.Maloni@va.gov Contact: Mitchell T Wallin, MD 2027458146 mitchell.wallin@va.gov United States, Oregon VA Portland Health Care System, Portland, OR Recruiting Portland, Oregon, United States, 97239 Contact: Carin Waslo 503-418-2141 waslo@ohsu.edu Contact: Cassidy A Taylor (503) 220-8262 Cassidy.Taylor@va.gov Principal Investigator: Rebecca I. Spain, MD MSPH United States, Utah University of Utah Recruiting Salt Lake City, Utah, United States, 84148 Contact: LaWanda Esquibel 801-587-3864 Lawanda.Esquibel@hsc.utah.edu Contact: Mateo Paz Soldan, MD miguel.pazsoldan@va.gov VA Salt Lake City Health Care System, Salt Lake City, UT Recruiting Salt Lake City, Utah, United States, 84148 Contact: Connie Kawai 323-442-5814 constance.kawai@med.usc.edu Contact: Lawanda Esquibel 8015873864 lawanda.esquibel@hsc.utah.edu United States, Vermont University of Vermont Recruiting Burlington, Vermont, United States, 05401 Contact: Roman Pettigrew 802-847-6039 Roman.Pettigrew@uvmhealth.org Contact: Andrew Solomon, MD 8028474589 Andrew.Solomon@uvmhealth.org United States, Washington VA Puget Sound Health Care System Seattle Division, Seattle, WA Not yet recruiting Seattle, Washington, United States, 98108 Contact: Alicia Sloan, MSW 800-329-8387 ext 63593 alicia.sloan@va.gov Contact: Jodie Haselkorn, MD Jodie.Haselkorn@va.gov Swedish Medical Center Recruiting Seattle, Washington, United States, 98122 Contact: Laura Johnson 206-320-7115 laura.johnson3@swedish.org Contact: Pavle Repovic, MD 2063202200 Pavle.Repovic@swedish.org Canada, Ontario Ottawa Hospital Research Institute Not yet recruiting Ottawa, Ontario, Canada, K1Y 4E9 Contact: Carol Freedman 613-737-8104 ext 2 cfreedman@toh.ca Contact: Mark Freedman, MD mfreedman@toh.ca Collapse << |
| NCT02056366 | Type 2 Diabetes ... more >> Cardiac Autonomic Neuropathy Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> The Catholic University of Korea Seoul, Korea, Republic of, 137-701 Eulji General Hospital Seoul, Korea, Republic of Sejong General Hospital Seoul, Korea, Republic of Collapse << |
| 靶点 | Description | IC50 |
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