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CAS No.: 130-95-0
Synonyms: NSC 192949;Chinin;Chininum
Quinine is a medication used to treat malaria and babesiosis, isolated from the bark of a cinchona tree.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01594827 | Cystic Fibrosis | Phase 2 | Completed | - | United States, Maryland ... more >> Johns Hopkins University School of Medicine Baltimore, Maryland, United States, 21205 United States, Ohio Rainbow Babies and Children's Hospital Cleveland, Ohio, United States, 44106 Collapse << |
NCT01594827 | - | - | Completed | - | - |
NCT02640495 | - | - | Withdrawn(Due to the relative ... more >>low incidence of severe malaria in Southeast Asia.) Collapse << | - | - |
实验方案
技术信息
CAS号 | 130-95-0 | 储存条件 |
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分子式 | C20H24N2O2 | 运输 | 蓝冰 | |||||
分子量 | 324.42 | 别名 | NSC 192949;Chinin;Chininum;6'-Methoxycinchonidine;Qualaquin;Quinamm;Quinbisan;Quinbisul;Quindan;奎宁 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01594827 | Cystic Fibrosis | Phase 2 | Completed | - | United States, Maryland ... more >> Johns Hopkins University School of Medicine Baltimore, Maryland, United States, 21205 United States, Ohio Rainbow Babies and Children's Hospital Cleveland, Ohio, United States, 44106 Collapse << |
NCT01594827 | - | - | Completed | - | - |
NCT02640495 | - | - | Withdrawn(Due to the relative ... more >>low incidence of severe malaria in Southeast Asia.) Collapse << | - | - |
NCT01399944 | - | - | Completed | - | United States, Pennsylvania ... more >> Monell Chemical Senses Center Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT03276481 | - | - | Recruiting | August 28, 2019 | United States, New York ... more >> Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10021 Contact: Sergio Giralt, MD 212-639-3859 Collapse << |
NCT03508349 | Malaria in Pregnancy | Not Applicable | Active, not recruiting | December 30, 2018 | Rwanda ... more >> Busoro-Gishamvu Health Center Huye, South, Rwanda Huye Police Health Center Huye, South, Rwanda Maraba Health Cente Huye, South, Rwanda Mukura Health Center Huye, South, Rwanda Rango Health Center Huye, South, Rwanda Rubona Health Center Huye, South, Rwanda Rwaniro Huye, South, Rwanda Sovu Health Center Huye, South, Rwanda Kamonyi Health Center Kamonyi, South, Rwanda Kayenzi Health Center Kamonyi, South, Rwanda Mugina Health Center Kamonyi, South, Rwanda Musambira Health Center Kamonyi, South, Rwanda Nyagihamba Health Center Kamonyi, South, Rwanda Nyamiyaga Health Center Kamonyi, South, Rwanda Collapse << |
NCT01340456 | CYP3A4 Induction | Not Applicable | Completed | - | Sweden ... more >> Clinical Pharmacology Trial Unit (CPTU), Karolinska University Hospital Stockholm, Sweden, SE-14186 Collapse << |
NCT00613743 | Cancer Mucosi... more >>tis Collapse << | Not Applicable | Completed | - | Switzerland ... more >> University Hospital Geneva Geneva, Collonge-bellerive, Switzerland, 1245 Collapse << |
NCT03525184 | Sleep Restriction | Not Applicable | Recruiting | December 2019 | United States, Massachusetts ... more >> U.S. Army Research Institute of Environmental Medicine Recruiting Natick, Massachusetts, United States, 01760 Contact: Tracey J Smith, PhD 508-233-4868 tracey.smith10.civ@mail.mil Collapse << |
NCT01144702 | Falciparum Malaria | Phase 2 Phase 3 | Completed | - | Brazil ... more >> Oswaldo Cruz Foundation Rio de Janeiro, Brazil, 21045-900 Institute of Biomedical Sciences, University of Sao Paulo São Paulo, Brazil, 05508-900 Collapse << |
NCT02171624 | Healthy | Phase 1 | Completed | - | - |
NCT00697164 | Cerebral Malaria | Phase 2 Phase 3 | Unknown | March 2009 | Mali ... more >> Gabriel Toure Hospital Recruiting Bamako, Mali Contact: Ogobara K DOUMBO, MD PhD 223-222-8109 okd@mrtcbko.org Contact: Salimata KONATE, MD 223-222-8109 salimata57@yahoo.fr Sub-Investigator: Salimata KONATE, MD Collapse << |
NCT00527800 | Malaria HIV I... more >>nfections Collapse << | Phase 3 | Completed | - | Uganda ... more >> Tororo District Hospital Tororo, Uganda Collapse << |
NCT00126971 | Malaria | Phase 1 | Suspended | - | Mali ... more >> Faladje Missionary Dispensary Faladje, Mali Collapse << |
NCT00342043 | - | - | Completed | - | Mali ... more >> Malaria Research and Training Center Bamako, Mali Collapse << |
NCT01231113 | Pregnancy Complicated by Malar... more >>ia as Antepartum Condition Collapse << | Phase 3 | Completed | - | Ghana ... more >> St.Michael's Hospital, Pramso Kumasi, Ashanti Region, Ghana Collapse << |
NCT01082718 | Malaria Pregn... more >>ancy Collapse << | Phase 2 Phase 3 | Withdrawn(Logistical difficult... more >>ies) Collapse << | October 2010 | - |
NCT00669084 | - | - | Completed | - | Mali ... more >> University of Bamako, Faculty of Medicine, Pharmacy and Odontostomatology Bamako, Mali Collapse << |
NCT02671175 | Malaria Sever... more >>e Anemia Collapse << | Phase 3 | Recruiting | March 2019 | Kenya ... more >> Homa Bay County Referral Hospital Recruiting Homa Bay, Homa Bay County, Kenya, 40100 Contact: Dr Titus k Kwambai, MSc +254723354238 titus.kwambai@lstmed.ac.uk Migori County Referral Hospital Recruiting Migori, Migori County, Kenya, 40400 Contact: Dr Grace M Nalwa, M.Med +254722263041 gmnalwa@gmail.com Contact: Dr Titus K Kwambai +254723354238 titus.kwambai@lstmed.ac.uk Siaya County Referral Hospital Recruiting Siaya, Siaya County, Kenya, 40100 Contact: Dr. Titus K Kwambai, MSc +254723354238 titus.kwambai@lstmed.ac.uk Uganda Hoima Regional Referral Hospital Recruiting Hoima, Uganda Contact: Dr Tom D Ediamu, M.Med +25677471388 Didimus@yahoo.com Contact: Dr Aggrey Dhabangi, M.Med +256772833789 adhabangi@gmail.com Jinja Regional Referral Hospital Recruiting Jinja, Uganda Contact: Dr Harriet L Nambuya, M.Med +256772448247 nambuyaharriet@yahoo.com Contact: Dr Aggrey Dhabangi, M.Med +256772833789 adhabangi@gmail.com Masaka Regional Referral Hospital Recruiting Masaka, Uganda Contact: Dr Aggrey Dhabangi, M.Med +256772833789 adhabangi@gmail.com Collapse << |
NCT03733262 | - | - | Not yet recruiting | March 1, 2020 | Canada, British Colombia ... more >> Providence Health Care Not yet recruiting Vancouver, British Colombia, Canada, V6Z 1Y6 Contact: Judith Marin, PharmD 604-806-8146 judith.marin@fraserhealth.ca Contact: Monica Beaulieu, MD 604 681-7191 MBeaulieu@providencehealth.bc.ca Canada, Manitoba Manitoba Renal Program Not yet recruiting Winnipeg, Manitoba, Canada, R2V 3M3 Contact: Cali Orsulak, PharmD 204 770-9312 COrsulak@hsc.mb.ca Contact: Clara Bohm, MD 204-787-3583 CBOHM@hsc.mb.ca Canada, Nova Scotia Nova Scotia Health Authority Not yet recruiting Halifax, Nova Scotia, Canada Contact: Jo-Anne Wilson, PharmD 902-473-5418 sjawilson@gmail.com Canada, Ontario University Health Network Not yet recruiting Toronto, Ontario, Canada, M5G 2C4 Contact: Marisa Batistella, PharmD 416-340-4800 ext 3207 marisa.battistella@uhn.ca Contact: Melissa Lefebvre, MBiotech 4168589786 melissa.lefebvre@uhnresearch.ca Collapse << |
NCT00701961 | Plasmodium Falciparum Malaria | Phase 2 Phase 3 | Completed | - | Burkina Faso ... more >> Centre Muraz Nanoro, Burkina Faso Collapse << |
NCT00341003 | - | - | Completed | - | Cambodia ... more >> Pursat Regional Health Center Pursat, Cambodia Collapse << |
NCT01641289 | Malaria | Not Applicable | Completed | - | Bangladesh ... more >> Chittagong Medical College Hospital Chittagong, Bangladesh Ramu Upazilla Health Complex Ramu, Bangladesh Collapse << |
NCT01814423 | Malaria | Phase 4 | Completed | - | Guinea-Bissau ... more >> Projecto de Saúde de Bandim Bissau, Guinea-Bissau, 1004 Collapse << |
NCT00812851 | Cramps Amyotr... more >>ophic Lateral Sclerosis Collapse << | Not Applicable | Completed | - | Switzerland ... more >> Kantonsspital St.Gallen St.Gallen, Switzerland, 9007 Collapse << |
NCT00157859 | Falciparum Malaria ... more >> Vivax Malaria Collapse << | Not Applicable | Completed | - | Indonesia ... more >> SP9 & SP12 Public Health- Malaria control clinics Timika, Papua, Indonesia Collapse << |
NCT02862353 | - | - | Recruiting | September 2020 | France ... more >> CHU de Saint Etienne Recruiting Saint Etienne, France, 42055 Contact: Claude LAMBERT, MD (0)4 77 12 05 13 Sub-Investigator: Anne-Emmanuelle BERGER, MD Sub-Investigator: Sandrine ACASSAT, MD Principal Investigator: Claude LAMBERT, MD Sub-Investigator: Elodie DE MAGALHAES, MD Collapse << |
NCT03140930 | Obesity | Not Applicable | Completed | - | Netherlands ... more >> Maastricht University Medical Center Maastricht, Limburg, Netherlands, 6229HX Collapse << |
NCT02642484 | Liver Cirrhosis | Phase 3 | Not yet recruiting | December 2022 | Egypt ... more >> Tanta university - faculty of medicine Tanta, Elgharbia, Egypt Collapse << |
NCT01707199 | Uncomplicated P. Falciparum Ma... more >>laria Collapse << | Not Applicable | Unknown | December 2013 | Afghanistan ... more >> Narang, Asadabad, Watapoor district health centres Recruiting Kunar, Afghanistan Contact: Ghulam Rahim Awab, MD awabgr@yahoo.com Principal Investigator: Ghulam Rahim Awab, MD Collapse << |
NCT00113854 | Cerebral Malaria | Phase 3 | Unknown | - | Uganda ... more >> Department of Paediatrics and Child Health, Makerere Medical School Kampala, Uganda, P O Box 7072 Collapse << |
NCT01157689 | - | - | Unknown | June 2014 | Guinea-Bissau ... more >> Bandim Health Project Bissau, Bissau Codex, Guinea-Bissau, 1004 Collapse << |
NCT03754322 | Malaria Pregn... more >>ancy Malaria Malaria in Pregnancy Collapse << | Not Applicable | Recruiting | January 31, 2020 | Canada, Alberta ... more >> University of Calgary Active, not recruiting Calgary, Alberta, Canada, T2L 2K8 Ethiopia Amhara Public Health Institute Recruiting Bahir Dar, Amhara, Ethiopia Contact: Banchamlak Tegegne +251582201698 banteg92@gmail.com Tropical & Infectious Diseases Research Center (TIDRC), Jimma University Active, not recruiting Jimma, Oromia, Ethiopia University of Gondar Active, not recruiting Gondar, Ethiopia Collapse << |
NCT01115439 | - | - | Completed | - | Afghanistan ... more >> Provincial Malaria Control Centers (MRC) Maimana, Faryab, Afghanistan Provincial Malaria Control Centers (MRC) Asadabad, Kunar, Afghanistan Provincial Malaria Control Centers (MRC) Jalalabad, Nangarhar, Afghanistan Provincial Malaria Control Centers (MRC) Taloqan, Afghanistan Collapse << |
NCT01956838 | Obesity | Not Applicable | Completed | - | Netherlands ... more >> Maastricht University Medical Center Maastricht, Netherlands Collapse << |
NCT02255812 | Exploratory Behavior | Not Applicable | Completed | - | Switzerland ... more >> University Hospital Basel, Switzerland, CH-4031 Collapse << |
NCT00715429 | Cramps | Not Applicable | Terminated(We exhausted potent... more >>ial candidates before reaching goal of 70; recruited 29, 29 completed the study) Collapse << | - | United States, Wisconsin ... more >> University of Wisconsin Madison, Wisconsin, United States, 53705 Collapse << |
NCT02390180 | - | - | Completed | - | United States, Indiana ... more >> Purdue University West Lafayette, Indiana, United States, 47907 Collapse << |
NCT00299208 | Plasmodium Falciparum Malaria | Phase 2 | Completed | - | Thailand ... more >> Mahidol University Hospital for Tropical Diseases Bangkok, Thailand, 10270 Collapse << |
NCT01289561 | Alcohol or Other Drugs Effects | Phase 1 | Completed | - | United States, Maryland ... more >> Behavioral Pharmacology Research Unit Baltimore, Maryland, United States, 21224 Collapse << |
NCT00451139 | Malaria | Phase 4 | Completed | - | Ethiopia ... more >> Jimma University Hospital Jimma, Ethiopia Collapse << |
NCT02974348 | Drug Resistant Malaria Due to ... more >>Plasmodium Falciparum Collapse << | Phase 3 | Completed | - | Cameroon ... more >> CDC Hospital Tiko, South west, Cameroon, 237 Collapse << |
NCT02276989 | Compliance Ch... more >>ronic Pain Collapse << | Phase 2 | Withdrawn(poor recruitment) | - | United States, District of Col... more >>umbia Georgetown University Washington, District of Columbia, United States, 20007 Collapse << |
NCT03149666 | - | - | Completed | - | - |
NCT02759926 | Healthy Obesi... more >>ty Collapse << | Not Applicable | Unknown | - | - |
NCT02902198 | Obesity | Not Applicable | Recruiting | July 2019 | Switzerland ... more >> University Hopital Basel Recruiting Basel, Switzerland Contact: Bettina Wölnerhanssen, Dr bettina.woelnerhanssen@usb.ch Collapse << |
NCT02492178 | Malaria | Phase 2 | Completed | - | Congo, The Democratic Republic... more >> of the Kinshasa School of Public Health Kinshasa, Congo, The Democratic Republic of the Collapse << |
NCT02630472 | Rhinitis Sinu... more >>sitis Collapse << | Phase 1 Phase 2 | Terminated(Institutional decis... more >>ion) Collapse << | - | United States, Pennsylvania ... more >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT01828333 | - | - | Completed | - | Congo, The Democratic Republic... more >> of the Centre de Santé CECO Kimpese, Bas Congo, Congo, The Democratic Republic of the Centre de Santé la Famille Kimpese, Bas Congo, Congo, The Democratic Republic of the Hôpital Général de Référence IME Kimpese, Bas Congo, Congo, The Democratic Republic of the Centre de Santé Ngeba Kisantu, Bas Congo, Congo, The Democratic Republic of the Hôpital Saint Luc de Kisantu Kisantu, Bas Congo, Congo, The Democratic Republic of the Centre de Santé Bita Maluku, Kinshasa, Congo, The Democratic Republic of the Centre de Santé Menkao Maluku, Kinshasa, Congo, The Democratic Republic of the Centre Hospitalier d'État de Maluku Maluku, Kinshasa, Congo, The Democratic Republic of the Centre Hospitalier Roi Baudoin 1er Masina Kinshasa, Congo, The Democratic Republic of the Collapse << |
NCT00639873 | Malaria | Not Applicable | Completed | - | Bangladesh ... more >> Bandarban Sadar Hospital Bandarban Sadar, Bandarban, Bangladesh Collapse << |
NCT02598713 | Pneumonia Asp... more >>iration Collapse << | Phase 1 | Recruiting | February 2019 | United States, Massachusetts ... more >> Massachussets General Hospital Recruiting Boston, Massachusetts, United States, 02114 Contact: Lorenzo Berra, MD 617-643-7733 Collapse << |
NCT02817919 | - | - | Completed | - | Ghana ... more >> Kintampo North Municipal Hospital Kintampo, Brong Ahafo Region, Ghana Princess Marie Louise Children's Hospital Accra, Greater Accra, Ghana Ridge Hospital Accra, Greater Accra, Ghana Agogo Presbytarian Hospital Agogo, Ghana Collapse << |
NCT02946970 | Healthy | Not Applicable | Completed | - | - |
NCT00322907 | Clinical Malaria | Phase 2 | Terminated | - | Papua New Guinea ... more >> Health centers Madang and Maprik, Madang and East Sepik Province, Papua New Guinea Collapse << |
NCT00471783 | Gingivitis | Phase 3 | Completed | - | Canada, British Columbia ... more >> Dr. Ian Low 2031 West 41st Avenue, Vancouver, British Columbia, Canada Collapse << |
NCT01374581 | Malaria | Phase 3 | Completed | - | Congo ... more >> Centre de Santé Lisungi Kinshasa, Mont-Ngafula, Congo, Route Kimwenza n°23 Uganda Kazo Health centre IV Kiruhura, Uganda, P.O Box 5 Rushere Collapse << |
NCT00000706 | HIV Infections | Not Applicable | Completed | - | United States, Maryland ... more >> Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 Collapse << |
NCT01047436 | Falciparum Malaria | Phase 2 | Completed | - | - |
NCT01047436 | - | - | Completed | - | - |
NCT00495508 | Malaria | Phase 4 | Completed | - | Uganda ... more >> Epicentre Mbarara, Mbarara District, Uganda Collapse << |
NCT01805232 | Malaria | Phase 4 | Unknown | July 2013 | Sudan ... more >> Kassala Recruiting Kassala, Sudan, 249 Contact: Abzinab A Ali, MD +249911259199 ext 122 ishagadamm@yahoo.com Principal Investigator: Tajeldien A Abdulla, MD Collapse << |
NCT00124267 | Cerebral Malaria | Phase 3 | Unknown | - | Uganda ... more >> Mulago Hospital Kampala, Uganda, 7051 Collapse << |
NCT02563704 | Malaria | Phase 3 | Completed | - | - |
NCT01851473 | Cocaine Use P... more >>harmacokinetics Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> National Institute on Drug Abuse Baltimore, Maryland, United States, 21224 Collapse << |
NCT00727272 | - | - | Completed | - | - |
NCT00167739 | Malaria | Phase 4 | Completed | - | Gabon ... more >> Medical Research Unit, Lambaréné Lambaréné, Moyen Ogooué, Gabon, B.P. 118 Collapse << |
NCT00806078 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> MDS Pharma Services Saint Laurent, Montreal, Quebec, Canada, H4R 2N6 Collapse << |
NCT00727272 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Fargo, North Dakota, United States, 56721 Collapse << |
NCT00806078 | - | - | Completed | - | - |
NCT00329134 | Malaria | Phase 2 | Completed | - | Rwanda ... more >> Centre Hospitalier De Butare Butare, Rwanda Collapse << |
NCT01258049 | Plasmodium Falciparum Malaria | Phase 3 | Completed | - | Burkina Faso ... more >> Centre National de Recherche et de Formation sur le Paludisme (CNRFP) Ouagadougou, Burkina Faso, 01 BP 2208 Ghana Navrongo Health Research Centre Navrongo, Ghana, P.O. Box 114 Rwanda Rwinkwavu District Hospital Rwinkwavu, Eastern Province, Rwanda Collapse << |
NCT02092766 | Anaemia | Phase 4 | Completed | - | Congo, The Democratic Republic... more >> of the Kinshasa School of Public Health Kinshasa, Congo, The Democratic Republic of the Collapse << |
NCT00726895 | Healthy | Phase 1 | Completed | - | - |
NCT00726895 | - | - | Completed | - | - |
NCT00779259 | - | - | Completed | - | - |
NCT03565133 | Obesity | Not Applicable | Recruiting | September 30, 2019 | Netherlands ... more >> Maastricht University Recruiting Venlo, Limburg, Netherlands, 5928 RC Contact: Tim Klaassen, MD +3143-3882134 t.klaassen@maastrichtuniversity.nl Contact: Annick E Alleleyn, MD +3143-3884190 a.alleleyn@maastrichtuniversity.nl Principal Investigator: Freddy J Troost, Dr. Collapse << |
NCT00785213 | Healthy | Phase 1 | Completed | - | United States, Minnesota ... more >> Cetero Research East Grand Forks, Minnesota, United States, 56721 Collapse << |
NCT00785213 | - | - | Completed | - | - |
NCT00779259 | Pharmacokinetics | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute Fargo, North Dakota, United States, 58104 Collapse << |
NCT00540202 | Uncomplicated Malaria | Phase 4 | Unknown | April 2008 | Uganda ... more >> Mulago National Referral Hospital Recruiting Kampala, Central, Uganda, 256 Contact: Jane Achan, MMed +256-772-410183 achanj@yahoo.co.uk Contact: Catherine Maiteki, MD +256-712-840449 cmaiteki@yahoo.com Sub-Investigator: Moses Kamya, MMed Collapse << |
NCT00785486 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> MDS Pharma Services Phoenix, Arizona, United States, 85044 Collapse << |
NCT00785486 | - | - | Completed | - | - |
NCT01258049 | - | - | Completed | - | - |
NCT00785980 | - | - | Completed | - | - |
NCT00785551 | Healthy Renal... more >> Impairment Collapse << | Phase 1 | Terminated(poor enrollment) | - | United States, Florida ... more >> Cetero Research Miami Gardens, Florida, United States, 33169 Collapse << |
NCT00726414 | Healthy | Phase 1 | Completed | - | - |
NCT00726414 | - | - | Completed | - | - |
NCT00785980 | Healthy | Phase 1 | Completed | - | - |
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