CAS No.: 1360614-48-7
(E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophen-2-yl)acrylamide Catalog No. CSN16088
Necrosulfonamide is a necroptosis inhibitor by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Wang H, Sun L, et al. Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. Mol Cell. 2014 Apr 10;54(1):133-146.
- [2] Sun L, Wang H, et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell. 2012 Jan 20;148(1-2):213-27.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1360614-48-7 | 储存条件 |
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| 分子式 | C18H15N5O6S2 | 运输 | 蓝冰 | |||||
| 分子量 | 461.47 | 别名 | ||||||
| 溶解度 |
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动物实验配方 |
