|(E)-4-((4-((4-(2-氰基乙烯基)-2,6-二甲基苯基)氨基)嘧啶-2-基)氨基)苯甲腈|CsnPharm

CAS No.: 500287-72-9

利匹韦林 Catalog No. CSN12729

Synonyms: R278474;TMC278;DB08864

Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with anti-HIV effect.

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靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Rilpivirine is a diarylpyrimidine derivative that functions as a non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infection. It demonstrated more pronounced activity against wild-type HIV-1 (EC50 = 0.4 nM) and all single and double mutants as compared to other NNRTIs, such as nevirapine, efavirenz, TMC120, and TMC125. Rilpivirine at 1 μM showed no sign of virus breakthrough for wild-type HIV-1 within 30 days. Compared to the E-isomer of rilpivirine, the Z-isomer exhibited relatively high potency against wild-type HIV-1 with an EC50 value of 0.6 nM, but showed five times less activity against single and double mutants. Rilpivirine inhibited 81% of the 1200 recombinant clinical isolates collected from HIV-infected patients with an EC50 value less than 1 nM. The IC₅₀ values of rilpivirine for the inhibition of CYP450 isoforms 3A4, 2C9, and 2D6 were 4.6, 5.0, and >10 μM, respectively. The pharmacokinetic studies after the i.v. administration of rilpivirine showed that the elimination half-life was 4.4 h in rat and 31h in dog. The exposure (AUC_inf) were 3.1 μg h/mL (i.v. dose of 4 mg/kg) in rat, 8.7 μg h/mL (i.v. dose of 1.25 mg/kg) in dog, 1.4 μg h/mL (i.v. dose of 1.25 mg/kg) in monkey, and 44 μg h/mL (i.v. dose of 1.25 mg/kg) in rabbit.
作用机制Rilpivirine is a NNRTI that shows potent activity against wild-type and mutant HIV-1 strains. The improved activity in comparison to other NNRTIs may involve a specific interaction of the cyano group in wing I with the indole ring of Trp229.
细胞研究

Cell Data

Cell Lines	Concentration	Assay Type	Time	Activity Description	Data Sources
human MT4 cells	-	Function assay	72 h	Antiviral activity against NNRTI-resistant HIV1 harboring reverse transcriptase Y188L mutant infected in human MT4 cells assessed as inhibition of viral replication after 72 hrs by HeLa-CD4-LTR-beta-gal assay, EC50=0.0037 μM	23137340
human PBMC cells	-	Function assay	-	Antiviral activity against Human immunodeficiency virus 1 subtype D isolate 92UG001 infected in human PBMC cells by cell based assay, EC50=0.00026 μM	19933797
human TZM-bl cells	-	Cytotoxicity assay	4 days	Cytotoxicity against human TZM-bl cells after 4 days by XTT assay, CC50=19.4 μM	22856541

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临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT02491242	-	-	Completed	-	Spain ... more >> Ramon y Cajal Hospital Madrid, Spain, 28034 Collapse <<
NCT02605954	HIV-1 Infection	Phase 3	Completed	-	-
NCT03631732	HIV-1 Infection	Phase 3	Recruiting	August 2020	-

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参考文献

[1] Azijn H, Tirry I, et al. TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1. Antimicrob Agents Chemother. 2010 Feb;54(2):718-27.
[2] Janssen PA, Lewi PJ, et al. In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl] -2,6-dimethylphenyl] amino] -2-pyrimidinyl] amino] benzonitrile (R278474, rilpivirine). J Med Chem. 2005 Mar 24;48(6):1901-9.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.7291 mL
- 13.6455 mL
- 27.2911 mL
- 5 mM
- 0.5458 mL
- 2.7291 mL
- 5.4582 mL
- 10 mM
- 0.2729 mL
- 1.3646 mL
- 2.7291 mL

技术信息

CAS号

500287-72-9

储存条件

粉末: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C22H18N6

运输

蓝冰

分子量

366.42

别名

R278474;TMC278;DB08864;Edurant;利匹韦林

溶解度

DMSO	73.0 mg/mL (199.2 mM)
Water	Insoluble
Ethanol	Insoluble

动物实验配方

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02491242	-	-	Completed	-	Spain ... more >> Ramon y Cajal Hospital Madrid, Spain, 28034 Collapse <<
NCT02605954	HIV-1 Infection	Phase 3	Completed	-	-
NCT03631732	HIV-1 Infection	Phase 3	Recruiting	August 2020	-
NCT02157311	HIV-1 Infection	Phase 3	Completed	-	France ... more >> Hôpital Meynard Fort-de-france, Martinique, France, 97261 Hôpital Avicenne Bobigny, France, 93000 CHU Côte de Nacre Caen, France, 14033 Centre Hospitalier Sud Francilien Corbeil Essonnes, France, 91100 Hôpital Le Bocage Dijon, France, 21079 Hôpital Raymond Poincaré Garches, France, 92380 Hôpital Bicêtre Kremlin Bicetre, France, 94275 Hôpital Gui de Chauliac Montpellier, France, 34295 Hôpital Saint-Antoine Paris, France, 75012 Hôpital Pitié-Salpêtrière Paris, France, 75013 Hôpital Européen Georges Pompidou Paris, France, 75015 Hôpital Necker Paris, France, 75015 Hôpital Bichat Paris, France, 75018 Hôpital Tenon Paris, France, 75020 Hôpital Foch Suresnes, France, 92151 Hôpital Purpan Toulouse, France, 31059 Hôpital Bretonneau Tours, France, 37044 Collapse <<
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NCT02605954	-	-	Completed	-	-
NCT01814722	-	-	Terminated(The trial was termi... more >>nated early due to slow recruitment.) Collapse <<	-	-
NCT02440789	HIV-1 Infection	Phase 1 Phase 2	Completed	-	-
NCT01495702	Acquired Immunodeficiency Synd... more >>rome HIV Infections Collapse <<	Phase 3	Completed	-	-
NCT00537966	HIV Infections	Not Applicable	Recruiting	January 2025	Switzerland ... more >> University of Zurich Recruiting Zurich, Switzerland Contact: Huldrych. Günthard Huldrych.guenthard@usz.ch Collapse <<
NCT00955968	HIV Infection	Phase 4	Completed	-	-
NCT01500616	Hepatitis C, Chronic	Phase 3	Completed	-	Belgium ... more >> Antwerpen, Belgium Brussel, Belgium Bruxelles, Belgium Charleroi, Belgium Gent, Belgium Leuven, Belgium Liège, Belgium Germany Berlin, Germany Bonn, Germany Dortmund, Germany Frankfurt, Germany Hannover, Germany Köln, Germany Stuttgart, Germany Tübingen, Germany Hungary Budapest, Hungary Ireland Dublin, Ireland Luxembourg Luxembourg, Luxembourg Portugal Amadora, Portugal Lisboa, Portugal Lisbon, Portugal Porto, Portugal Russian Federation Perm, Russian Federation Saint-Petersburg, Russian Federation St Petersburg, Russian Federation Toliatti, Russian Federation Volgograd, Russian Federation Yoshkar - Ola, Russian Federation United Kingdom Glasgow, United Kingdom Liverpool, United Kingdom London, United Kingdom Plymouth, United Kingdom Collapse <<
NCT01495702	-	-	Completed	-	-
NCT03256422	HIV Infections	Phase 3	Active, not recruiting	December 2020	-
NCT01814722	-	-	Terminated(The trial was termi... more >>nated early due to slow recruitment.) Collapse <<	-	-
NCT02660905	Human Immunodeficiency Virus ... more >> Hepatitis C, Chronic Collapse <<	Phase 3	Active, not recruiting	December 2017	Canada, Ontario ... more >> The Ottawa Hospital, General Campus Ottawa, Ontario, Canada Canada, Quebec The Research Institute of the McGill University Health Centre Montreal, Quebec, Canada, H4A 3J1 Collapse <<
NCT01908660	-	-	Completed	-	Spain ... more >> Hospital Universitario de Valme Seville, Spain, 41014 Collapse <<
NCT02397096	HIV-1 Infection	Phase 3	Active, not recruiting	November 2, 2021	-
NCT00955968	-	-	Completed	-	-
NCT03635788	HIV Infections	Phase 3	Not yet recruiting	June 22, 2024	United States, California ... more >> University of Southern California CRS Not yet recruiting Los Angeles, California, United States, 90033-1079 Contact: Luis M. Mendez 323-343-8283 lmendez@usc.edu UCLA CARE Center CRS Not yet recruiting Los Angeles, California, United States, 90035 Contact: Arezou S. Akha, M.D., M.S. 310-557-3798 asadighi@mednet.ucla.edu UCSD Antiviral Research Center CRS Not yet recruiting San Diego, California, United States, 92103 Contact: Jill Kunkel, R.N. 619-543-8080 jkunkel@ucsd.edu Ucsf Hiv/Aids Crs Not yet recruiting San Francisco, California, United States, 94110 Contact: Jay Dwyer 415-476-4082 ext 353 Jay.Dwyer@ucsf.edu Harbor-UCLA CRS Not yet recruiting Torrance, California, United States, 90502 Contact: Mario Guerrero 424-201-3000 ext 7318 mguerrero@labiomed.org United States, Colorado University of Colorado Hospital CRS Not yet recruiting Aurora, Colorado, United States, 80045 Contact: Suzanne Fiorillo, M.S.P.H. 303-724-5931 suzanne.fiorillo@ucdenver.edu United States, Georgia The Ponce de Leon Center CRS Not yet recruiting Atlanta, Georgia, United States, 30308-2012 Contact: Ericka Patrick, M.S.N. 404-616-6313 erpatri@emory.edu United States, Massachusetts Massachusetts General Hospital CRS (MGH CRS) Not yet recruiting Boston, Massachusetts, United States, 02114 Contact: Theresa Flynn, R.N., M.S.N., A.N.P., B.S.N. 617-724-0072 tflynn@partners.org Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS Not yet recruiting Boston, Massachusetts, United States, 02115 Contact: Cheryl E. Keenan, R.N. 617-732-5635 CKeenan@BWH.Harvard.edu United States, Missouri Washington University Therapeutics (WT) CRS Not yet recruiting Saint Louis, Missouri, United States, 63110-1010 Contact: Michael K. Klebert 314-747-1098 mklebert@dom.wustl.edu United States, New York Weill Cornell Chelsea CRS Not yet recruiting New York, New York, United States, 10010 Contact: Todd Stroberg, R.N., B.S.N. 212-746-7198 tstrober@med.cornell.edu Columbia P&S CRS Not yet recruiting New York, New York, United States, 10032-3732 Contact: Steven Palmer, P.A. -C 212-342-2958 sp500@cumc.columbia.edu Weill Cornell Uptown CRS Not yet recruiting New York, New York, United States, 10065 Contact: Rebecca Fry, M.S.N., FNP 212-746-4166 ref2007@med.cornell.edu United States, North Carolina Chapel Hill CRS Not yet recruiting Chapel Hill, North Carolina, United States, 27599 Contact: Becky Straub, B.S.N., M.P.H. 919-843-9975 bstraub@med.unc.edu Greensboro CRS Not yet recruiting Greensboro, North Carolina, United States, 27401 Contact: Kim Epperson, R.N., B.S.N., CRC 336-832-3262 kim.epperson@conehealth.com United States, Ohio Cincinnati Clinical Research Site Not yet recruiting Cincinnati, Ohio, United States, 45219 Contact: Sharon Kohrs, R.N., B.S.N. 513-584-6383 kohrssd@ucmail.uc.edu Case Clinical Research Site Not yet recruiting Cleveland, Ohio, United States, 44106 Contact: Jane Baum, R.N. 216-844-2546 jb@clevelandactu.org United States, Pennsylvania Penn Therapeutics, CRS Not yet recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Eileen B. Donaghy, C.R.N.P. 215-349-8092 eileen.donaghy2@uphs.upenn.edu United States, Rhode Island The Miriam Hospital Clinical Research Site (TMH CRS) CRS Not yet recruiting Providence, Rhode Island, United States, 02906 Contact: Pamela Poethke, R.N. 401-793-4971 ppoethke@lifespan.org United States, Tennessee Vanderbilt Therapeutics (VT) CRS Not yet recruiting Nashville, Tennessee, United States, 37204 Contact: Beverly O. Woodward, M.S.N., R.N. 615-936-8516 beverly.o.woodward@vanderbilt.edu United States, Washington University of Washington AIDS CRS Not yet recruiting Seattle, Washington, United States, 98104-9929 Contact: Christine Jonsson 206-744-8886 cjonsson@u.washington.edu Puerto Rico Puerto Rico AIDS Clinical Trials Unit CRS Not yet recruiting San Juan, Puerto Rico, 00935 Contact: Sylvia I. Davila Nieves, M.Sc. 787-767-9192 sylvia.davila1@upr.edu San Juan City Hosp. PR NICHD CRS Not yet recruiting San Juan, Puerto Rico, 00936 Contact: Lizbeth Fabregas-Troche, B.S., M.S. 787-764-3083 lfabregas@sanjuanciudadpatria.com Collapse <<
NCT02547844	HIV-1	Phase 4	Completed	-	Spain ... more >> Hospital Universitari Vall d'Hebron Barcelona, Spain, 08035 Collapse <<
NCT02447016	HIV	Phase 4	Terminated(no more participant... more >>s taking atripla) Collapse <<	-	Israel ... more >> Sheba Medical Center Ramat Gan, Israel, 52621 Collapse <<
NCT03194165	-	-	Recruiting	June 2019	France ... more >> Cochin Hospital Recruiting Paris, France, 75014 Contact: Jean-Marc TRELUYER, MD, PhD +33 1 58 41 28 84 jean-marc.treluyer@aphp.fr Principal Investigator: Jean-Marc TRELUYER, MD, PhD Collapse <<
NCT02470650	Patient Compliance ... more >> Antiretroviral Therapy Intolerance Collapse <<	Phase 4	Unknown	October 2017	Spain ... more >> Josep Mallolas Masferrer Recruiting Barcelona, Spain, 08025 Contact: Joan Albert Arnaiz, MD 932275400 ext 3898 jaarnaiz@clinic.ub.es Contact: ana Cruceta, MD acruceta@clinic.ub.es Collapse <<
NCT02799264	Infection, Human Immunodeficie... more >>ncy Virus Collapse <<	Phase 1	Completed	-	United States, Kansas ... more >> GSK Investigational Site Overland Park, Kansas, United States, 66211 Collapse <<
NCT02196064	-	-	Completed	-	Spain ... more >> Fundación Pública Andaluza Progreso y Salud Sevilla, Spain, 41092 Collapse <<
NCT01701895	-	-	Completed	-	United States, North Carolina ... more >> University of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States, 27599-7215 Collapse <<
NCT02308332	Neurocognitive Decline ... more >> HIV Associated Neurocognitive Disorder Collapse <<	Phase 4	Completed	-	Netherlands ... more >> UMC Utrecht Utrecht, Netherlands Collapse <<
NCT01792570	Human Immunodeficiency Virus	Phase 3	Unknown	October 2017	Italy ... more >> Clinica delle Malattie Infettive, Policlinico Universitario Recruiting Bari, BA, Italy Contact: Gioacchino Angarano, M.D. g.angarano@clininf.uniba.it Principal Investigator: Gioacchino Angarano, M.D. Divisione di Malattie Infettive, Ospedale S. Maria Annunziata, Antella Recruiting Firenze, FI, Italy Contact: Sergio Lo Caputo, M.D. sergio.locaputo@asf.toscana.it Principal Investigator: Sergio Lo Caputo, M.D. Clinica delle Malattie Infettive, Ospedale San Martino, Università degli Studi Recruiting Genova, GE, Italy Contact: Antonio Di Biagio, M.D. antonio.dibiagio@hsanmartino.it Principal Investigator: Antonio Di Biagio, M.D. Divisione di Malattie Infettive, Ospedale San Gerardo Recruiting Monza, MB, Italy Contact: Andrea Gori, M.D. andrea.gori@unimib.it Principal Investigator: Andrea Gori, M.D. Divisione Clinicizzata di Malattie Infettive dell'Università degli Studi, Dipartimento di Scienze Biomediche e Cliniche "Luigi Sacco" Recruiting Milano, MI, Italy, 20157 Contact: Stefano Rusconi, M.D. stefano.rusconi@unimi.it Contact: Elisa Colella, M.D. elisa_colella@yahoo.it Principal Investigator: Stefano Rusconi, M.D. I e II Divisione Malattie Infettive, Azienda Ospedaliera-Polo Universitario "Luigi Sacco" Recruiting Milano, MI, Italy, 20157 Contact: Giuliano Rizzardini, M.D. rizzardini.giuliano@hsacco.it Principal Investigator: Giuliano Rizzardini, M.D. Clinica Malattie Infettive, Policlinico Universitario Not yet recruiting Modena, MO, Italy Contact: Cristina Mussini, M.D. crimuss@unimore.it Principal Investigator: Cristina Mussini, M.D. U.O. Malattie Infettive, Policlinico S. Matteo Recruiting Pavia, PV, Italy Contact: Renato Maserati, M.D. rmaserati@smatteo.pv.it Principal Investigator: Renato Maserati, M.D. Clinica delle Malattie Infettive, Policlinico "Tor Vergata" Recruiting Roma, RM, Italy Contact: Massimo Andreoni, M.D. andreoni@uniroma2.it Contact: Loredana Sarmati, M.D. sarmati@med.uniroma2.it Principal Investigator: Massimo Andreoni, M.D. Istituto di Clinica delle Malattie Infettive, Università Cattolica del Sacro Cuore Not yet recruiting Roma, RM, Italy Contact: Simona Di Giambenedetto, M.D. simona.digiambenedetto@rm.unicatt.it Principal Investigator: Simona Di Giambenedetto, M.D. U.O. Malattie Infettive, Azienda Policlinico Umberto I, Università degli Studi "La Sapienza" Recruiting Roma, RM, Italy Contact: Vincenzo Vullo, M.D. vincenzo.vullo@uniroma1.it Contact: Gabriella D'Ettorre, M.D. gabriella.dettorre@uniroma1.it Principal Investigator: Vincenzo Vullo, M.D. Clinica delle Malattie Infettive, Ospedale Amedeo di Savoia, Università degli Studi Recruiting Torino, TO, Italy Contact: Stefano Bonora, M.D. stefano.bonora@unito.it Principal Investigator: Stefano Bonora, M.D. Collapse <<
NCT02120352	Infection, Human Immunodeficie... more >>ncy Virus Collapse <<	Phase 2	Active, not recruiting	December 31, 2020	-
NCT02345226	HIV-1 Infection	Phase 3	Active, not recruiting	December 2018	-
NCT02345226	-	-	Active, not recruiting	-	-
NCT03639311	HIV Infections	Phase 2	Not yet recruiting	November 30, 2020	United States, Florida ... more >> GSK Investigational Site Not yet recruiting Fort Lauderdale, Florida, United States, 33316 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com United States, Texas GSK Investigational Site Not yet recruiting Dallas, Texas, United States, 75246 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com Collapse <<
NCT02345252	HIV-1 Infection	Phase 3	Active, not recruiting	December 2018	-
NCT02345252	-	-	Active, not recruiting	-	-
NCT02707601	-	-	Completed	-	-
NCT01309243	HIV-1 Infection	Phase 3	Completed	-	-
NCT01309243	-	-	Completed	-	-
NCT02042001	Impaired Cognition ... more >> Depression/Anxiety Poor Quality Sleep Quality of Life HIV-1 Infection Collapse <<	Phase 4	Completed	-	Italy ... more >> Clinic of Infectious Diseases, AO San Gerardo Monza, MB, Italy, 20900 Spedali Civili - University of Brescia Brescia, Italy Clinica di Malattie Infettive, Ospedale San Martino Genova, Italy AO San Paolo - University of Milan Milan, Italy Ospedale Amedeo di Savoia - University of Turin Torino, Italy Collapse <<
NCT02478632	HIV Infections	Phase 3	Completed	-	-
NCT02478632	-	-	Completed	-	-
NCT02707601	HIV-1 Infection ... more >> HCV Infection Collapse <<	Phase 3	Completed	-	-
NCT01205139	Hepatitis C Virus	Phase 1	Completed	-	-
NCT03518060	-	-	Recruiting	December 1, 2021	Germany ... more >> GSK Investigational Site Not yet recruiting Tuebingen, Baden-Wuerttemberg, Germany, 72076 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Muenchen, Bayern, Germany, 80331 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Muenchen, Bayern, Germany, 80335 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Muenchen, Bayern, Germany, 80336 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Muenchen, Bayern, Germany, 80801 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Muenchen, Bayern, Germany, 81675 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Osnabrueck, Niedersachsen, Germany, 49090 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Aachen, Nordrhein-Westfalen, Germany, 52062 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Bochum, Nordrhein-Westfalen, Germany, 44787 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Koeln, Nordrhein-Westfalen, Germany, 50674 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Muenster, Nordrhein-Westfalen, Germany, 48143 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Berlin, Germany, 10117 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Berlin, Germany, 10243 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Berlin, Germany, 10707 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Berlin, Germany, 10777 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Berlin, Germany, 12163 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Berlin, Germany, 14057 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Berlin, Germany, 14059 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Recruiting Chemnitz, Germany, 09111 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Hamburg, Germany, 20099 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Hamburg, Germany, 20146 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Koeln, Germany, 50668 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com GSK Investigational Site Not yet recruiting Weimar, Germany, 99427 Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com Collapse <<
NCT03251690	Anti-Retroviral Agents ... more >> Efavirenz HIV-1-infection Sustained Virologic Response Dyslipidemias Rilpivirine Collapse <<	Not Applicable	Active, not recruiting	March 31, 2018	-
NCT01286740	-	-	Completed	-	-
NCT01252940	HIV-1 Infection	Phase 3	Completed	-	-
NCT01593046	Infection, Human Immunodeficie... more >>ncy Virus Collapse <<	Phase 1	Completed	-	United States, Florida ... more >> GSK Investigational Site Daytona Beach, Florida, United States, 32117 United States, Kansas GSK Investigational Site Overland Park, Kansas, United States, 66211 Collapse <<
NCT01777997	HIV-1 Infection	Phase 4	Completed	-	United States, Alabama ... more >> 31788 Alabama CRS Birmingham, Alabama, United States, 35294 United States, California 801 University of California, San Francisco HIV/AIDS CRS San Francisco, California, United States, 94110 United States, District of Columbia Whitman Walker Health CRS (31791) Washington, District of Columbia, United States, 20009 United States, Georgia The Ponce de Leon Ctr. CRS (5802) Atlanta, Georgia, United States, 30308 United States, Illinois Northwestern University CRS (2701) Chicago, Illinois, United States, 60611 Rush Univ. Med. Ctr. ACTG CRS (2702) Chicago, Illinois, United States, 60612 United States, Maryland IHV Baltimore Treatment CRS (4651) Baltimore, Maryland, United States, 21201 United States, Massachusetts Massachusetts General Hospital ACTG CRS (101) Boston, Massachusetts, United States, 02114 Brigham and Women's Hosp. ACTG CRS (107) Boston, Massachusetts, United States, 02115 United States, New York Bronx-Lebanon Hosp. Ctr. CRS (31469) Bronx, New York, United States, 10457 University of Rochester Adult HIV Therapeutic Strategies Network CRS (31787) Rochester, New York, United States, 14642 United States, North Carolina Unc Aids Crs (3201) Chapel Hill, North Carolina, United States, 27516 Moses H. Cone Memorial Hospital CRS (3203) Greensboro, North Carolina, United States, 27401 United States, Ohio University of Cincinnati CRS (2401) Cincinnati, Ohio, United States, 45267 Metro Health CRS (2503) Cleveland, Ohio, United States, 44109 United States, Pennsylvania Hosp. of the Univ. of Pennsylvania CRS (6201) Philadelphia, Pennsylvania, United States, 19104 Pitt CRS (1001) Pittsburgh, Pennsylvania, United States, 15213 United States, Rhode Island The Miriam Hosp. ACTG CRS (2951) Providence, Rhode Island, United States, 02906 United States, Texas Houston AIDS Research Team CRS (31473) Houston, Texas, United States, 77030 Collapse <<
NCT01777997	-	-	Completed	-	-
NCT01286740	HIV-1 Infection	Phase 2	Completed	-	United States, California ... more >> Living Hope Clinical Foundation Long Beach, California, United States, 90814 Peter J. Ruane MD Inc Los Angeles, California, United States, 90036 Anthony Mills MD, Inc. Los Angeles, California, United States, 90069 La Playa Medical Group and Clinical Research San Diego, California, United States, 92103 United States, District of Columbia Dupont Circle Physicians Group, P.C. Washington, District of Columbia, United States, 20009 Whitman Walker Clinic Washington, District of Columbia, United States, 20009 Capital Medical Associates, PC Washington, District of Columbia, United States, 20036 United States, Florida The Kinder Medical Group Miami, Florida, United States, 33133 Orlando Immunology Center Orlando, Florida, United States, 32803 United States, Georgia Atlanta ID Group Atlanta, Georgia, United States, 30309 Infectious Disease Specialists of Atlanta Decatur, Georgia, United States, 30033 United States, Illinois Northstar Medical Center Chicago, Illinois, United States, 60657 United States, Massachusetts Community Research Initiative of New England Boston, Massachusetts, United States, 02215 United States, Michigan Be Well Medical Center, P.C. Berkley, Michigan, United States, 48072 United States, Missouri Southampton Healthcare, Inc. St. Louis, Missouri, United States, 63139 United States, Texas Southwest Infectious Disease Clinical Research, Inc. Addison, Texas, United States, 75001 Central Texas Clinical Research Austin, Texas, United States, 78705 United States, Washington Peter Shalit, M.D. Seattle, Washington, United States, 98104 Collapse <<
NCT02429791	HIV Infections	Phase 3	Active, not recruiting	August 13, 2021	-
NCT01252940	-	-	Completed	-	-
NCT03299049	HIV Infections	Phase 3	Active, not recruiting	March 11, 2022	-
NCT02422797	HIV Infections	Phase 3	Active, not recruiting	August 12, 2021	-
NCT02529059	HIV	Phase 4	Completed	-	United Kingdom ... more >> Brighton & Sussex University Hospitals Nhs Trust Brighton, United Kingdom St. Mary's Hospital London, United Kingdom St. Stephen's Centre London, United Kingdom Collapse <<
NCT01641809	Infection, Human Immunodeficie... more >>ncy Virus Collapse <<	Phase 2	Active, not recruiting	November 20, 2018	-
NCT02938520	HIV Infections	Phase 2 Phase 3	Active, not recruiting	July 7, 2022	-
NCT02422797	-	-	Active, not recruiting	-	-
NCT01796431	HIV	Phase 1	Completed	-	United Kingdom ... more >> St Stephen's AIDS Trust London, United Kingdom, SW10 9NH Collapse <<
NCT00543725	HIV Infections ... more >> HIV-1 Collapse <<	Phase 3	Completed	-	-
NCT01336829	Hepatitis C H... more >>IV Collapse <<	Phase 1	Completed	-	Belgium ... more >> Antwerp, Belgium Collapse <<
NCT00543725	-	-	Completed	-	-
NCT02882230	-	-	Not yet recruiting	February 2020	-
NCT02741557	Infection, Human Immunodeficie... more >>ncy Virus Collapse <<	Phase 1	Completed	-	United States, Kansas ... more >> GSK Investigational Site Overland Park, Kansas, United States, 66211 Collapse <<
NCT02429791	-	-	Active, not recruiting	-	-
NCT02373930	Infection, Human Immunodeficie... more >>ncy Virus Collapse <<	Phase 1	Completed	-	United States, Kansas ... more >> GSK Investigational Site Overland Park, Kansas, United States, 66211 Collapse <<
NCT00110305	Human Immunodeficiency Virus T... more >>ype 1 Collapse <<	Phase 2	Completed	-	-
NCT00110305	-	-	Completed	-	-
NCT00812292	Pharmacokinetics ... more >> Bioavailability HIV-1 Collapse <<	Phase 1	Completed	-	-
NCT00855335	HIV HIV Infec... more >>tions Pregnancy Collapse <<	Phase 3	Completed	-	United States, Florida ... more >> Daytona Beach, Florida, United States Jacksonville, Florida, United States Miami, Florida, United States Pensacola, Florida, United States Port Saint Lucie, Florida, United States West Palm Beach, Florida, United States United States, Georgia Savannah, Georgia, United States United States, Illinois Chicago, Illinois, United States United States, Massachusetts Springfield, Massachusetts, United States United States, Michigan Dearborn, Michigan, United States United States, New York Bronx, New York, United States Syracuse, New York, United States United States, North Carolina Chapel Hill, North Carolina, United States Greensboro, North Carolina, United States United States, Pennsylvania Philadelphia, Pennsylvania, United States United States, Texas Bellaire, Texas, United States Puerto Rico San Juan Pr, Puerto Rico Collapse <<
NCT00741741	HIV-1	Phase 1	Terminated(Strategic decision)	-	-
NCT00540449	HIV Infections ... more >> HIV-1 Human Immunodeficiency Virus Type 1 Collapse <<	Phase 3	Completed	-	-
NCT00855335	-	-	Completed	-	-
NCT00744809	Human Volunteers	Phase 1	Completed	-	-
NCT00744770	HIV	Phase 1	Completed	-	-
NCT01031589	HIV Infections	Phase 1	Completed	-	-
NCT00739622	HIV AIDS ... more >> Oral Contraceptive Collapse <<	Phase 1	Completed	-	-
NCT00736905	HIV AIDS ... more >> Hepatic Impairment Collapse <<	Phase 1	Completed	-	-
NCT00540449	-	-	Completed	-	-
NCT01709084	Human Immunodeficiency Virus-t... more >>ype 1 Infection Collapse <<	Phase 3	Active, not recruiting	December 31, 2020	Cameroon ... more >> Douala, Cameroon Yaounde, Cameroon Kenya Eldoret, Kenya Kangemi, Nairobi, Kenya Nairobi, Kenya Nyanza, Kenya Senegal Dakar, Senegal Pikine, Senegal South Africa Bloemfontein, South Africa Johannesburg, South Africa Soweto, South Africa Wentworth, Durban, South Africa Westville, Kwazulu, South Africa Thailand Amphur Mueang Nonthaburi, Thailand Bangkok, Thailand Chiang Mai, Thailand Uganda Entebbe, Uganda Kampala, Uganda Collapse <<
NCT01715636	HIV Nonoccupational Post-expos... more >>ure Prophylaxis in Men Who Have Sex With Men Collapse <<	Phase 4	Completed	-	Australia, New South Wales ... more >> Sydney Sexual Heatlh Centre Sydney, New South Wales, Australia, 2000 St Vincents Hospital Sydney, New South Wales, Australia, 2010 Australia, Victoria The Alfred Hospital Melbourne, Victoria, Australia, 3004 Melbourne Sexual Health Centre Melbourne, Victoria, Australia, 3053 Collapse <<
NCT01709084	-	-	Active, not recruiting	-	-
NCT02069834	HIV Infection ... more >> HAART-treated Virologically Controlled Collapse <<	Phase 2 Phase 3	Withdrawn(One of the both Fund... more >>er partners decided to stop the study before the initiation thus no product provided and no funding to realize the study) Collapse <<	October 2017	France ... more >> CHU Guadeloupe Point-a-pitre, Guadeloupe, France, 97159 CHU de Fort de France Fort de France, Martinique, France, 87261 Chu Jean Minjoz Besançon, France, 25030 Hôpital Avicenne Bobigny, France, 93000 Hôpital Jean Verdier Bondy, France, 93140 CHU de Bordeaux Bordeaux, France, 33076 CHU de DIJON Dijon, France, 21079 CHD La Roche sur Yon La Roche sur Yon, France, 85925 CHU Kremlin Bicêtre Le Kremlin Bicetre, France, 94275 Hôpital Perpetuel Secours Levallois-perret, France, 92300 CHU de Nantes Nantes, France, 44093 Hôpital Saint Louis Paris Cedex 10, France, 75475 CHU BICHAT - Claude Bernard Paris cedex 18, France, 75877 CHU Hôtel Dieu Paris Paris, France, 75004 Hôpital La Pitié Salpêtrière Paris, France, 75013 Hôpital Necker - enfants Malades Paris, France, 75015 Hôpital Européen Georges Pompidou Paris, France, 75908 CHU de Rennes - Hôpital Pontchaillou Rennes, France, 35000 CH Delafontaine Saint Denis, France, 93200 CHU Saint Etienne Saint Etienne, France, 42055 CHU de Strasbourg Strasbourg, France, 67091 Hôpital FOCH Suresnes, France, 92150 CHU Toulouse Toulouse, France, 31059 CHRU de Tours Tours Cedex 09, France, 37044 CHU de Nancy VANDOEUVRE LES NANCY cedex, France, 54511 Collapse <<
NCT01467531	Infections, Human Immunodefici... more >>ency Virus and Hepatitis Collapse <<	Phase 1	Completed	-	United States, New York ... more >> GSK Investigational Site Buffalo, New York, United States, 14202 Collapse <<
NCT03589040	HIV Contracep... more >>tion Collapse <<	Phase 2	Not yet recruiting	June 2020	Uganda ... more >> Infectious Diseases Institue Not yet recruiting Kampala, Uganda, 256 Contact: Stephen Research Manager 0392878652 sokoboi@idi.co.ug Principal Investigator: Mohammed Lamorde, PhD Sub-Investigator: Kimberley Scarsi, PharmD,MSc Sub-Investigator: Catherine Chappell, MD, MSc Sub-Investigator: Saye Khoo, PhD Sub-Investigator: Pauline Byakika, PhD Sub-Investigator: Kristin Darin, PharmD Sub-Investigator: Shadia Nakalema, MBChB, DTM&H Sub-Investigator: Stephen Walimbwa, MD Sub-Investigator: Julian Kaboggoza, BPharm Collapse <<
NCT03497676	HIV Infections	Phase 1 Phase 2	Not yet recruiting	August 2023	United States, Colorado ... more >> Univ. of Colorado Denver NICHD CRS Not yet recruiting Aurora, Colorado, United States, 80045 Contact: Emily Barr, C.P.N.P., C.N.M., M.S.N. 720-777-6752 emily.barr@childrenscolorado.org United States, Maryland Johns Hopkins Univ. Baltimore NICHD CRS Not yet recruiting Baltimore, Maryland, United States, 21287 Contact: Aleisha Collinson-Streng, R.N., A.C.R.N. 443-801-7301 acolli14@jhmi.edu United States, New York Bronx-Lebanon Hospital Center NICHD CRS Not yet recruiting Bronx, New York, United States, 10457 Contact: Martha Cavallo, A.N.P., C.R.N.P. 718-960-1010 mcavallo@bronxleb.org Jacobi Med. Ctr. Bronx NICHD CRS Not yet recruiting Bronx, New York, United States, 10461 Contact: Marlene Burey, R.N., M.S.N., P.N.P. 718-918-4783 marlene.burey@nychhc.org United States, Tennessee St. Jude Children's Research Hospital CRS Not yet recruiting Memphis, Tennessee, United States, 38105-3678 Contact: Patricia M. Flynn, M.D. 901-595-2338 pat.flynn@stjude.org United States, Washington Seattle Children's Research Institute CRS Not yet recruiting Seattle, Washington, United States, 98101 Contact: Amanda Robson Nuss, B.S. 206-884-1535 amanda.robson@seattlechildrens.org Puerto Rico San Juan City Hosp. PR NICHD CRS Not yet recruiting San Juan, Puerto Rico, 00936 Contact: Lizbeth Fabregas-Troche, B.S., M.S. 787-764-3083 lfabregas@sanjuanciudadpatria.com Collapse <<
NCT01975012	HIV Infections	Phase 1 Phase 2	Withdrawn	-	-
NCT01275443	HIV Infection	Phase 1	Completed	-	United Kingdom ... more >> St Stephen's AIDS Trust London, United Kingdom, SW10 9NH Collapse <<
NCT02951052	Infection, Human Immunodeficie... more >>ncy Virus Collapse <<	Phase 3	Active, not recruiting	February 8, 2022	-
NCT01049932	HIV Infections	Phase 1 Phase 2	Terminated(Trial closed due to... more >> additional safety information.) Collapse <<	-	United Kingdom ... more >> Royal Sussex County Hospital Brighton, Sussex, United Kingdom, BN2 5BE St. Thomas's Hospital London, United Kingdom, SE1 7EH St Stephen's Centre London, United Kingdom, SW10 9TH St. Mary's Hospital London, United Kingdom, W2 1NY Collapse <<
NCT01001247	HIV Infections	Phase 1	Completed	-	-
NCT01266902	HIV-1 Infection	Phase 3	Active, not recruiting	December 31, 2021	-
NCT01519128	Healthy	Phase 1	Completed	-	Belgium ... more >> Merksem, Belgium Collapse <<
NCT00799864	Human Immuno Deficiency (HIV) ... more >>Infection Collapse <<	Phase 2	Recruiting	August 20, 2027	United States, New York ... more >> SUNY Upstate Medical University Recruiting Syracuse, New York, United States, 13210 United States, Tennessee St Jude Children's Research Hospital Completed Memphis, Tennessee, United States, 38105 United States, Virginia Children'S Hospital of the King'S Daughters Withdrawn Norfolk, Virginia, United States, 23507 India Yr Gaitonde Center For Aids Research and Education Completed Chennai, India, 600113 Kasturba Medical College Hospital Completed Mangalore, India, 575001 Kenya Kenya Medical Research Institute/Walter Reed Project Not yet recruiting Kericho, Kenya, 20200 KAVI Institute of Clinical Research Recruiting Nairobi, Kenya, 254 Romania Spitalul de Boli Infectioase si Tropicale 'Dr. Victor Babes' Completed Bucuresti, Romania, 030317 South Africa Boanerges Clinical Research Completed Bloemfontein, South Africa, 9301 Josha Research Recruiting Bloemfontein, South Africa, 9301 Jan Fourie Medical Practice Completed Dundee, South Africa, 3000 University of KwaZulu-Natal Withdrawn Durban, South Africa, 4001 Harriet Shezi Childrens Clinic, Paediatric Department Withdrawn Johannesburg Gauteng, South Africa, 2013 Mzansi Ethical Research Centre Recruiting Middelburg, South Africa, 1055 Triple M Research Withdrawn Port Elizabeth, South Africa, 6070 Synexuss Sastanza Completed Pretoria, South Africa, 0122 Limpopo Clinical Research Initiative Recruiting Thabazimbi, South Africa, 380 East Rand Urology Research Unit Not yet recruiting Vosloorus, South Africa, 1475 Thailand Thai Red Cross Aids Research Centre Completed Bangkok, Thailand, 10330 Queen Sirikit National Institute of Child Health Withdrawn Bangkok, Thailand, 10400 Bamrasnaradura Infectious Disease Institute Recruiting Nonthaburi, Thailand, 11000 Uganda Mrc/ Uvri Uganda Research Unit on Aids Not yet recruiting Entebbe, Uganda Joint Clinical Research Centre Recruiting Kampala, Uganda, 10005 Makerere University Medical School Withdrawn Kampala, Uganda Ukraine Center Clinic for treatment HIV positive children Completed Kiev, Ukraine, 01135 Collapse <<
NCT01804244	Healthy	Phase 4	Completed	-	Japan ... more >> Tokyo, Japan Collapse <<
NCT01268839	HIV	Phase 1	Completed	-	-
NCT03127189	Healthy	Phase 1	Completed	-	United States, Arizona ... more >> Celerion Tempe, Arizona, United States, 85283 United States, Nebraska Celerion Lincoln, Nebraska, United States, 68502 Collapse <<
NCT01736761	HIV	Phase 4	Completed	-	United Kingdom ... more >> St Stephen's AIDS Trust London, United Kingdom, SW10 9TH Collapse <<
NCT01701882	HIV	Phase 3	Completed	-	United Kingdom ... more >> St Stephen's AIDS Trust London, United Kingdom, SW10 9TH Collapse <<
NCT01585038	Cardiovascular Disease	Phase 4	Completed	-	United States, Indiana ... more >> Indiana Clinical and Translational Sciences Institute Indianapolis, Indiana, United States, 46202 Collapse <<
NCT01585038	-	-	Completed	-	-
NCT01656018	Healthy	Phase 1	Completed	-	United States, Pennsylvania ... more >> Pittsburgh, Pennsylvania, United States Collapse <<
NCT03567304	HIV-1-infection ... more >> Neurocognitive Dysfunction Collapse <<	Phase 4	Recruiting	July 2020	Thailand ... more >> Chiang Mai University Hospital Recruiting Chiang Mai, Thailand, 50200 Contact: Quanhathai Kaewpoowat, MD 6653936148 quanhathai@rihes.org Contact: Wirongrong Thongton, MD 6653936148 wirongrong1983@gmail.com Collapse <<
NCT02104700	HIV	Phase 2 Phase 3	Unknown	July 2016	Rwanda ... more >> Rwanda Military Hospital Kinombe, Rwanda Collapse <<
NCT01692470	-	-	Withdrawn(The company decided ... more >>to cancel this study in conformity with Philippines FDA Circular 2013-004) Collapse <<	December 2015	-
NCT02165202	Human Immunodeficiency Virus (... more >>HIV) Collapse <<	Phase 2	Completed	-	United States, New Jersey ... more >> New Jersey Medical School Clinical Research Center Newark, New Jersey, United States, 07103 United States, New York Bronx Prevention Center Bronx, New York, United States, 10451 South Africa Emavundleni Clinical Research Site Cape Town, South Africa Zimbabwe Spilhaus Clinical Research Site Belgravia, Harare, Zimbabwe Collapse <<
NCT01288755	HIV Infections	Phase 1	Completed	-	-
NCT01719614	Healthy Participants	Phase 1	Completed	-	United States, Kansas ... more >> Overland Park, Kansas, United States Collapse <<
NCT03664440	Efficacy of Rilpivirine-based ... more >>Regimens as Switch Therapy Collapse <<	Not Applicable	Completed	-	Thailand ... more >> Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University Bangkok, Thailand Collapse <<
NCT02561936	Healthy	Phase 1	Completed	-	Belgium ... more >> Antwerp, Belgium Collapse <<
NCT02404233	HIV Positive	Phase 4	Unknown	December 2016	United States, Texas ... more >> Therapeutic Concepts, P.A. Not yet recruiting Houston, Texas, United States, 77004 Contact: Joseph C. Gathe, M.D. 713-526-9821 drgathe@josephgathe.com Contact: Valerie H. Davis, B.S. 713-526-9821 vdavis@josephgathe.com Principal Investigator: Joseph C. Gathe, M.D. Therapeutic Concepts, PA Houston, Texas, United States, 77004 Collapse <<
NCT01615614	Healthy	Phase 1	Completed	-	Belgium ... more >> Merksem, Belgium Collapse <<
NCT02547870	Human Immunodeficiency Virus T... more >>ype 1 Collapse <<	Phase 1	Completed	-	Belgium ... more >> Antwerp, Belgium Collapse <<
NCT02165202	-	-	Completed	-	-
NCT03589027	HIV-1-infection ... more >> Contraception Collapse <<	Phase 2	Recruiting	June 2020	Uganda ... more >> Infectious Diseases Institue Recruiting Kampala, Uganda, 256 Contact: Stephen Research Manager 0392878652 sokoboi@idi.co.ug Principal Investigator: Mohammed Lamorde, PhD Sub-Investigator: Kimberley Scarsi, PharmD,MSc Sub-Investigator: Catherine Chappell, MD, MSc Sub-Investigator: Saye Khoo, PhD Sub-Investigator: Pauline Byakika, PhD Sub-Investigator: Kristin Darin, PharmD Sub-Investigator: Shadia Nakalema, MBChB, DTM&H Sub-Investigator: Stephen Walimbwa, MD Sub-Investigator: Julian Kaboggoza, BPharm Collapse <<
NCT02530060	Healthy	Phase 4	Completed	-	Japan ... more >> Fukuoka, Japan Collapse <<
NCT01562886	HIV	Phase 1	Completed	-	United Kingdom ... more >> Imperial College Healthcare NHS Trust London, United Kingdom, W2 1NY Collapse <<
NCT03033368	HIV	Phase 2 Phase 3	Enrolling by invitation	December 2017	-
NCT01562886	-	-	Completed	-	-
NCT02494986	Human Immunodeficiency Virus T... more >>ype 1 Collapse <<	Phase 2	Recruiting	November 4, 2031	South Africa ... more >> Josha Research Recruiting Bloemfontein, South Africa, 9301 Jan Fourie Medical Practice Completed Dundee, South Africa, 2930 Collapse <<
NCT03563742	Human Immunodeficiency Virus I... more >>nfections Collapse <<	Phase 3	Recruiting	August 31, 2020	India ... more >> St.Johns Medical College and Hospital Not yet recruiting Bengaluru, India, 560034 YRGCARE Not yet recruiting Chennai, India, 600113 Manipal University-Kasturba Medical College Recruiting Mangalore, India, 575001 Lata Mangeshkar Hospital Recruiting Nagpur, India, 440001 Deenanath Mangeshkar Hospital and Research Centre Recruiting Pune, India, 411004 Collapse <<

利匹韦林 Catalog No. CSN12729

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