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CAS No.: 842133-18-0
Synonyms: JNJ 28431754;TA 7284;JNJ-24831754
Canagliflozin is a novel C-glucoside with thiophene ring.
生物活性
靶点 | SGLT2 IC50:4.4nM | SGLT2 (mouse) IC50:2nM | SGLT2 (rat) IC50:3.7nM |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02053116 | Type 2 Diabetes Mellitus | Phase 2 | Terminated(On 25April2014, stu... more >>dy was terminated before any dosing due to an AE of safety concern that occurred in protocol B1731003 with the same drug.) Collapse << | - | United States, Florida ... more >> Pfizer Investigational Site DeLand, Florida, United States, 32720 Collapse << |
NCT00650806 | - | - | Completed | - | - |
NCT01273558 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | Germany ... more >> Neuss, Germany Collapse << |
实验方案
技术信息
CAS号 | 842133-18-0 | 储存条件 |
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分子式 | C24H25FO5S | 运输 | 蓝冰 | |||||||||||
分子量 | 444.52 | 别名 | JNJ 28431754;TA 7284;JNJ-24831754;INJ24831754;JNJ24831754AAA;JNJ24831754ZAE;Trade name: Invokana;卡格列净 | |||||||||||
溶解度 |
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动物实验配方 |
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Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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CHO-K1 cells | - | Function assay | - | Inhibition of human SGLT2 expressed in CHO-K1 cells by [14C]AMG uptake assay, IC50=6.7 nM | 22652255 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02053116 | Type 2 Diabetes Mellitus | Phase 2 | Terminated(On 25April2014, stu... more >>dy was terminated before any dosing due to an AE of safety concern that occurred in protocol B1731003 with the same drug.) Collapse << | - | United States, Florida ... more >> Pfizer Investigational Site DeLand, Florida, United States, 32720 Collapse << |
NCT00650806 | - | - | Completed | - | - |
NCT01273558 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | Germany ... more >> Neuss, Germany Collapse << |
NCT01756404 | Healthy | Phase 1 | Completed | - | United States, Florida ... more >> Miramar, Florida, United States Collapse << |
NCT00650806 | Obesity | Phase 2 | Completed | - | - |
NCT02920918 | Heart Failure, Systolic ... more >> Diabetes Mellitus, Type 2 Collapse << | Phase 4 | Active, not recruiting | March 2019 | United States, Virginia ... more >> Virginia Commonwealth University Richmond, Virginia, United States, 23298 Collapse << |
NCT02681497 | - | - | Completed | - | Canada, Ontario ... more >> Western University London, Ontario, Canada, N6A 3K7 Collapse << |
NCT01714206 | Healthy | Phase 1 | Completed | - | - |
NCT01032629 | Diabetes Mellitus, Type 2 ... more >> Cardiovascular Diseases Risk Factors Collapse << | Phase 3 | Completed | - | - |
NCT01459094 | Healthy | Phase 1 | Completed | - | - |
NCT02737657 | - | - | Completed | - | Kuwait ... more >> Kuwait City, Kuwait Lebanon Amioun, Lebanon Beirut, Lebanon Nabatieh, Lebanon Saida, Lebanon Taalabya, Lebanon Tripoli, Lebanon United Arab Emirates Al Ain, United Arab Emirates Dubai, United Arab Emirates Collapse << |
NCT02220907 | - | - | Completed | - | - |
NCT02220907 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | Japan ... more >> Research site Chubu, Japan Research site Chugoku, Japan Research site Hokkaido, Japan Research site Kanto, Japan Research site Kyushu, Japan Research site Tohoku, Japan Collapse << |
NCT01032629 | - | - | Completed | - | - |
NCT01463774 | Healthy | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
NCT02354222 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | Japan ... more >> Reserch site Kanto, Japan Reserch site Kinki, Japan Reserch site Tohoku, Japan Collapse << |
NCT02354222 | - | - | Completed | - | - |
NCT01665638 | Healthy | Phase 1 | Completed | - | Germany ... more >> Neuss, Germany Collapse << |
NCT02846506 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT02851212 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT02694263 | Diabetes Mellitus, Type 2 | Phase 4 | Recruiting | September 2018 | United Kingdom ... more >> University Hospitals of Leicester NHS Trust Recruiting Leicester, Leicestershire, United Kingdom, LE5 4PW Contact: Emer Brady, PhD 0116248 ext 8959 emer.brady@uhl-tr.nhs.uk Contact: Natasha Wileman, MSc 0116258 ext 8929 natasha.wileman@uhl-tr.nhs.uk University Hospitals Birmingham NHS Foundation Trust Recruiting Birmingham, West Midlands, United Kingdom, B15 2TH Contact: Wasim Hanif 0121371 ext 4404 wasim.hanif@uhb.nhs.uk Contact: Deborah Smith 0121371 ext 4707 deborah.smith@uhb.nhs.uk Collapse << |
NCT00968812 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT00968812 | - | - | Completed | - | - |
NCT03267576 | Diabetes Mellitus, Type 2 | Phase 4 | Completed | - | Mexico ... more >> Consultorio Privado Guadalajara, Mexico, 44150 Investigación Clínica Especializada Guadalajara, Mexico, 44600 Consultorio Privado en Unidad de Patología Clínica Guadalajara, Mexico, 44650 Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán Mexico City, Mexico, 14080 Hospital Universitario 'Dr. Jose Eleuterio Gonzalez' Monterrey, Mexico, 64460 Collapse << |
NCT01787357 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT01916863 | Healthy Subjects | Phase 1 | Completed | - | United States, California ... more >> Lexicon Investigational Site Chula Vista, California, United States, 91911 Collapse << |
NCT01106677 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT01748526 | Healthy | Phase 1 | Completed | - | India ... more >> Ahmedabad, India Collapse << |
NCT01759576 | Renal Insufficiency ... more >> Healthy Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> Orlando, Florida, United States United States, Minnesota Minneapolis, Minnesota, United States United States, Tennessee Knoxville, Tennessee, United States Collapse << |
NCT01381887 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | United States, California ... more >> Chula Vista, California, United States United States, Florida Miramar, Florida, United States United States, Ohio Cincinnati, Ohio, United States United States, Texas Dallas, Texas, United States San Antonio, Texas, United States Collapse << |
NCT02851095 | Healthy | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
NCT02865668 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT01106690 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT02220920 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | Japan ... more >> Reserch site Chubu, Japan Reserch site Chugoku, Japan Reserch site Hokkaido, Japan Reserch site Kanto, Japan Reserch site Kinki, Japan Reserch site Kyushu, Japan Reserch site Tohoku, Japan Collapse << |
NCT02220920 | - | - | Completed | - | - |
NCT02360774 | - | - | Completed | - | - |
NCT01821027 | Healthy | Phase 1 | Completed | - | - |
NCT01483781 | Diabetes Mellitus, Type 2 ... more >> Plasma Volume Collapse << | Phase 1 | Completed | - | Germany ... more >> Neuss, Germany Collapse << |
NCT01106677 | - | - | Completed | - | - |
NCT01137812 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT01137812 | - | - | Completed | - | - |
NCT03136484 | Diabetes Diab... more >>etes Mellitus, Type 2 Collapse << | Phase 3 | Completed | - | - |
NCT02025907 | - | - | Completed | - | - |
NCT01106690 | - | - | Completed | - | - |
NCT02025907 | Diabetes Mellitus, Type 2 | Phase 4 | Completed | - | - |
NCT01106625 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT02360774 | Type 2 Diabetes ... more >> Overweight Obesity Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 Collapse << |
NCT01173549 | Healthy | Phase 1 | Completed | - | United States, California ... more >> La Jolla, California, United States Collapse << |
NCT01106625 | - | - | Completed | - | - |
NCT02462421 | Diabetes Mellitus ... more >> Gout Hyperuricemia Collapse << | Phase 4 | Enrolling by invitation | September 2019 | - |
NCT01508182 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT01508195 | Healthy | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
NCT01756417 | Healthy | Phase 1 | Completed | - | United States, New Jersey ... more >> Neptune, New Jersey, United States Collapse << |
NCT02009488 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | United States, California ... more >> San Diego, La Jolla, California, United States United States, Florida Gainesville, Florida, United States Collapse << |
NCT02039258 | Healthy Volunteers | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
NCT01106651 | - | - | Completed | - | - |
NCT01106651 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT01081834 | - | - | Completed | - | - |
NCT01939496 | - | - | Completed | - | - |
NCT01989754 | Diabetes Mellitus, Type 2 ... more >> Albuminuria Collapse << | Phase 4 | Completed | - | - |
NCT01939496 | Diabetes Mellitus, Type 2 ... more >> Hypertension Collapse << | Phase 4 | Completed | - | - |
NCT01733108 | Healthy | Phase 1 | Completed | - | - |
NCT01081834 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT01809327 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT01989754 | - | - | Completed | - | - |
NCT02077803 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT02354235 | - | - | Completed | - | - |
NCT02354235 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | Japan ... more >> Reserch site Kanto, Japan Reserch site Kinki, Japan Reserch site Tohoku, Japan Collapse << |
NCT02071368 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT01281579 | Healthy | Phase 1 | Completed | - | - |
NCT01381900 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | China ... more >> Baotou, China Beijing, China Changchun, China Changsha, China Chengdu, China Chongqing, China Guangzhou, China Hangzhou, China Harbin, China Nanchang, China Nanjing, China Nanning, China Shanghai, China Shenyang, China Shiyan, China Siping, China Su Zhou, China Tianjin, China Wuxi, China Xi'An, China Malaysia Kota Bharu, Malaysia Pulau Pinang, Malaysia Selangor, Malaysia Vietnam Hanoi, Vietnam Ho Chi Minh, Vietnam Collapse << |
NCT01809327 | - | - | Completed | - | - |
NCT02065791 | Diabetes Mellitus, Type 2 ... more >> Diabetic Nephropathy Collapse << | Phase 3 | Active, not recruiting | June 28, 2019 | - |
NCT01381900 | - | - | Completed | - | - |
NCT01463228 | Healthy | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
NCT01454622 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT02404870 | Diabetes PTH ... more >> Vitamin D Fibroblast Growth Factor (FGF23) Phosphate Collapse << | Phase 1 | Recruiting | May 1, 2019 | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 prpl@cc.nih.gov Collapse << |
NCT01195324 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Merksem, Belgium Collapse << |
NCT01791231 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Merksem, Belgium Collapse << |
NCT01286103 | Healthy | Phase 1 | Completed | - | - |
NCT01128985 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | United States, Florida ... more >> Fort Myers, Florida, United States Miramar, Florida, United States Collapse << |
NCT02065752 | Healthy Volunteers | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT02227849 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | Japan ... more >> Reserch site Chubu, Japan Reserch site Hokkaido, Japan Reserch site Kanto, Japan Reserch site Kinki, Japan Collapse << |
NCT01340664 | Diabetes Mellitus, Type 2 | Phase 2 | Completed | - | - |
NCT01518712 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT01340664 | - | - | Completed | - | - |
NCT02622113 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | Japan ... more >> Reserch site Chubu, Japan Reserch site Chugoku, Japan Reserch site Hokkaido, Japan Reserch site Kanto, Japan Reserch site Kinki, Japan Reserch site Kyushu, Japan Reserch site Tohoku, Japan Collapse << |
NCT02688075 | - | - | Completed | - | Canada, Alberta ... more >> Calgary, Alberta, Canada Edmonton, Alberta, Canada Canada, British Columbia Coquitlam, British Columbia, Canada Surrey, British Columbia, Canada Canada, Manitoba Winnipeg, Manitoba, Canada Canada, Ontario Brampton, Ontario, Canada Downsview, Ontario, Canada Guelph, Ontario, Canada London, Ontario, Canada Mississauga, Ontario, Canada Ohsweken, Ontario, Canada Ottawa, Ontario, Canada Smiths Falls, Ontario, Canada Toronto, Ontario, Canada Canada, Quebec Laval, Quebec, Canada Longueuil, Quebec, Canada Montreal, Quebec, Canada Saint-Jean-Sur-Richelieu, Quebec, Canada Sherbrooke, Quebec, Canada St Marc Des Carrieres, Quebec, Canada Toronto, Quebec, Canada Westmont, Quebec, Canada Canada, Saskatchewan Saskatoon, Saskatchewan, Canada Collapse << |
NCT02039245 | Healthy Volunteers | Phase 1 | Completed | - | United States, New Jersey ... more >> Neptune, New Jersey, United States Collapse << |
NCT01064414 | Diabetes Mellitus, Type 2 ... more >> Renal Insufficiency Collapse << | Phase 3 | Completed | - | - |
NCT01294631 | Healthy | Phase 1 | Completed | - | - |
NCT01395927 | Healthy | Phase 1 | Completed | - | United States, Kansas ... more >> Overland Park, Kansas, United States Collapse << |
NCT01340677 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Merksem, Belgium Collapse << |
NCT01064414 | - | - | Completed | - | - |
NCT01714193 | Healthy | Phase 1 | Completed | - | - |
NCT03170518 | Diabetes Mellitus, Type 2 | Phase 3 | Recruiting | June 30, 2021 | - |
NCT01273571 | Healthy | Phase 1 | Completed | - | - |
NCT01343290 | Healthy | Phase 1 | Completed | - | - |
NCT02243202 | Obesity | Phase 2 | Completed | - | United States, Arizona ... more >> Phoenix, Arizona, United States United States, California Walnut Creek, California, United States United States, Florida Jacksonville, Florida, United States United States, Idaho Meridian, Idaho, United States United States, Indiana Evansville, Indiana, United States United States, Kentucky Lexington, Kentucky, United States Louisville, Kentucky, United States United States, Louisiana New Orleans, Louisiana, United States United States, Massachusetts Milford, Massachusetts, United States United States, New York Manlius, New York, United States United States, Rhode Island Warwick, Rhode Island, United States United States, South Carolina Mt Pleasant, South Carolina, United States United States, Tennessee Nashville, Tennessee, United States United States, Texas Dallas, Texas, United States Odessa, Texas, United States United States, Virginia Norfolk, Virginia, United States United States, Wisconsin Wauwatosa, Wisconsin, United States Collapse << |
NCT02139943 | - | - | Completed | - | - |
NCT02964585 | Type 2 Diabetes Mellitus | Phase 4 | Recruiting | May 2019 | United States, District of Col... more >>umbia The George Washington University Medical Faculty Associates Recruiting Washington, District of Columbia, United States, 20037 Contact: Fiona Dore, BS 202-741-2342 fdore@mfa.gwu.edu Collapse << |
NCT02221180 | Bioequivalence | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
NCT03298009 | Type2 Diabetes ... more >> Heart Failure Collapse << | Not Applicable | Withdrawn(end of contract nego... more >>ciations) Collapse << | January 1, 2019 | - |
NCT02139943 | Diabetes Mellitus, Type 1 | Phase 2 | Completed | - | - |
NCT01428284 | Healthy | Phase 1 | Completed | - | United States, Kansas ... more >> Overland Park, Kansas, United States Collapse << |
NCT02073227 | Healthy Volunteers | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT01707316 | Healthy | Phase 1 | Completed | - | China ... more >> Beijing, China Collapse << |
NCT02243202 | - | - | Completed | - | - |
NCT03436693 | Diabetic Nephropathy | Phase 3 | Recruiting | September 2021 | Japan ... more >> Research site Recruiting Aichi, Japan Research site Recruiting Chiba, Japan Research site Recruiting Fukuoka, Japan Research site Recruiting Fukushima, Japan Research site Recruiting Gunma, Japan Research site Recruiting Hiroshima, Japan Research site Recruiting Hokkaido, Japan Research site Recruiting Hyogo, Japan Research site Recruiting Ibaraki, Japan Research site Recruiting Kagawa, Japan Research site Recruiting Kagoshima, Japan Research site Recruiting Kanagawa, Japan Research site Recruiting Kumamoto, Japan Research site Recruiting Mie, Japan Research site Recruiting Nagano, Japan Research site Recruiting Nagasaki, Japan Research site Recruiting Oita, Japan Research site Recruiting Okinawa, Japan Research site Recruiting Osaka, Japan Research site Recruiting Saitama, Japan Research site Recruiting Shizuoka, Japan Research site Recruiting Tochigi, Japan Research site Recruiting Tokyo, Japan Research site Recruiting Wakayama, Japan Research site Recruiting Yamagata, Japan Research site Recruiting Yamaguchi, Japan Collapse << |
NCT02220218 | Healthy | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
NCT02597309 | Diabetes, Obesity | Phase 4 | Withdrawn | July 2017 | United States, Massachusetts ... more >> Joslin Diabetes Center Boston, Massachusetts, United States, 02215 Collapse << |
NCT02324842 | Type 2 Diabetes Mellitus | Not Applicable | Recruiting | December 2018 | United States, Texas ... more >> University of Texas Health Science Center at San Antonio Recruiting San Antonio, Texas, United States, 78229 Contact: Ralph A DeFronzo, MD 210-567-6691 defronzo@uthscsa.edu Contact: Monica Palomo, BS 210-567-6710 palomom@uthscsa.edu Principal Investigator: Ralph A DeFronzo, MD Collapse << |
NCT01186588 | Healthy Hepat... more >>ic Insufficiency Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> Orlando, Florida, United States United States, Tennessee Knoxville, Tennessee, United States Collapse << |
NCT01877889 | Healthy | Phase 1 | Completed | - | Germany ... more >> Neuss, Germany Collapse << |
NCT03604224 | - | - | Recruiting | March 29, 2019 | India ... more >> Diacon Hospital Recruiting Bangalore, India, 560010 Dr. A. Ramachandran's Diabetes Hospitals Not yet recruiting Chennai, India, 600032 CARE Hospitals Not yet recruiting Hydrabad, India, 500001 Collapse << |
NCT02624908 | Diabetes Mellitus, Type 2 | Phase 4 | Recruiting | November 2018 | United States, Georgia ... more >> Atlanta VA Medical Center Recruiting Decatur, Georgia, United States, 30033 Collapse << |
NCT01718652 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Antwerpen, Belgium Collapse << |
NCT03190798 | Type2 Diabetes Mellitus ... more >> Cardiovascular Diseases Collapse << | Phase 4 | Withdrawn(Study has been withd... more >>rawn from IRB review pending IND revision) Collapse << | August 1, 2018 | United States, Texas ... more >> The University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229 Collapse << |
NCT02891954 | Diabetes Mellitus, Type 2 | Phase 1 | Enrolling by invitation | June 30, 2023 | - |
NCT02673138 | Type 1 Diabetes | Not Applicable | Completed | - | United States, Connecticut ... more >> Yale University School of Medicine New Haven, Connecticut, United States, 06520 Collapse << |
NCT02673138 | - | - | Completed | - | - |
NCT02000700 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | United States, Arkansas ... more >> Little Rock, Arkansas, United States United States, California Los Angeles, California, United States United States, Colorado Aurora, Colorado, United States United States, Connecticut New Haven, Connecticut, United States United States, Florida Jacksonville, Florida, United States United States, Indiana Indianapolis, Indiana, United States United States, Kansas Lenexa, Kansas, United States United States, Maryland Baltimore, Maryland, United States United States, Missouri Kansas City, Missouri, United States United States, Ohio Toledo, Ohio, United States United States, Pennsylvania Pittsburgh, Pennsylvania, United States United States, Texas Houston, Texas, United States United States, Utah Salt Lake City, Utah, United States Brazil Campinas, Brazil Curitiba, Brazil Ribeirão Preto, Brazil Sao Paulo, Brazil Collapse << |
NCT01157000 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Merksem, Belgium Collapse << |
NCT02912455 | Diabetes Mellitus, Type 2 ... more >> Obesity Collapse << | Phase 4 | Recruiting | July 31, 2018 | United States, Ohio ... more >> Cleveland Clinic Recruiting Cleveland, Ohio, United States, 44195 Contact: Sangeeta Kashyap, MD 216-445-2679 kashyas@ccf.org Contact: Mario Scarcipino 216-444-3599 mascar@ccf.org Principal Investigator: Sangeeta Kashyap, MD Collapse << |
靶点 | Description | IC50 |
---|---|---|
SGLT2 | IC50:4.4nM | |
SGLT2 (mouse) | IC50:2nM | |
SGLT2 (rat) | IC50:3.7nM |
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