CAS No.: 492-14-8
(-)-Butin Catalog No. CSN13945
Synonyms: Butin
(-)-Butin, a natural product isolated and purfied from the seeds of Cassia tora, acts against H2O2-induced apoptosis were exerted via blockade of membrane potential depolarization, inhibition of the JNK pathway and mitochondria-involved caspase-dependent apoptotic pathway, enhancing the expression of phosphorylated Akt (active form of Akt), a regulator of OGG1.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03299751 Late-Onset Neonatal Sepsis Not Applicable Recruiting November 2019 France ... more >> Hospices Civils de Lyon Recruiting Bron, France, 69500 Contact: Marine Butin, MD 04 27 85 52 84 ext +33 marine.butin@chu-lyon.fr Collapse << - 参考文献
- [1] Park MH, Kim IS, et al. Inhibitory effect of Rhus verniciflua Stokes extract on human aromatase activity; butin is its major bioactive component. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1730-3.
- [2] Zhang R, Chae S, et al. The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway. J Cell Biochem. 2012 Jun;113(6):1987-97.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 492-14-8 | 储存条件 |
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| 分子式 | C15H12O5 | 运输 | 蓝冰 | |
| 分子量 | 272.25 | 别名 | Butin |
