|Verinurad is an inhibitor of urate transporter with EC50 of 0.05 μM.
|Lesinurad sodium is an inhibitor of URAT1 and OAT and it is also a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.
|Lesinurad is a URAT1 inhibitor with IC50 of 3.5 µM. It acts as a transporter that regulates uric acid excretion in kidney.
|Fraxin protects HUVECs from oxidative stress, enhances urate excretion partly by inhibiting mURAT1 or mGLUT9 in kidney of hyperuricemic mice. It is a natural product isolated and purified from the bark of Fraxinus brngeana DC..
|URAT1 inhibitor 1