Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane. Because glucose is a vital source of energy for all life, these transporters are present in all phyla.
|WZB117 is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 μM.
|STF-31 is a glucose transporter 1 (GLUT1) inhibitor with IC50 of 1 μM.
|Lavendustin B is a competitive Glut1 inhibitor with Ki value of 15µM.
|GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Preferentially inhibits GLUT4 over GLUT1.
|cis-ACBD is a competitive and selective inhibitor of glutamate uptake.
|Bis-dehydro-L-ascorbicacid is the blood-brain barrier transportable form of vitamin C and acts as GLUT1 substrate.
|BAY-876 is a selective inhibitor of GLUT1 with IC50 of 0.002 μM with good metabolic stability.