|UAMC-3203 is a potent and selective Ferroptosis inhibitor with IC50 of 12 nM.
|UAMC-3203 HCl is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
|SRS16-86, a ferrostatin analog, is a novel third-generation inhibitor of ferroptosis. It is the first compound in this class that is stable in plasma and liver microsomes and that demonstrates high efficacy when supplied alone or in combination therapy.
|RSL3 is a ferroptosis activator in a VDAC-independent manner, exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.
|Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.
|IKE (Imidazole ketone erastin )
|IKE is a potent, metabolically stable inhibitor of system Xc- and inducer of ferroptosis potentially suitable for in vivo applications.
|iFSP1 is a FSP1 (Ferroptosis suppressor protein 1) inhibitor.
|FIN56 is a ferroptosis activator and glutathione peroxidase 4 (GPX4) degradation inducer. It also bound to and activated squalene synthase (SQS), an enzyme involved in isoprenoid biosynthesis.
|Ferrostatin-1 is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
|Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products. Butylated hydroxytoluene is a Ferroptosis inhibitor.