|YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP.
|YHO-13351 free base
|YHO-13351 free base is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP.
|YHO-13177 is a selective and potent inhibitor of BCRP, it potentiates the cytotoxicity of SN-38 in cancer cells and has no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells.
|ML753286 is a potent inhibitor for BCRP, but not for P-glycoprotein (P-gp), organic anion-transporting polypeptide (OATP), or major cytochrome P450s (CYPs).
|KS176 is a potent and selective inhibitor for the breast cancer resistance protein (BCRP) multidrug transporter with IC50s of 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively.
|Ko 143 is a practical breast cancer resistance protein multidrug transporter inhibitor BCRP, with the EC90 value of 26 nM.
|Glafenine hydrochloride is a non-narcotic analgesic and non-steroidal anti-inflammatory drug and an ABCG2 inhibitor with an IC50 of 3.2 μM.