|Xanthoxylin is a naturally occuring phenolic ketone (C10H12O4) present in plants such as the Brazilian plant Sebastiania schottiana, possessing cytotoxic and fungicidal effect.
|Xanthatin, a natural product isolated and purified from the fruits of Xanthium sibiricum with cytotoxic, antibacterial and antifungal activities, can inhibit murine melanoma B16-F10 cell proliferation possibly associated with activation of Wnt/β-catenin pathway and its activity against melanoma tumor might also be relevant to inhibition of angiogenesis.
|Wighteone, a natural product isolated and purified from the herbs of Glycyrrhiza glabra, has excellent anti-yeast activity.
|Vibunazole is a new antifungal azole.
|Undecanoic acid is a medium chain length monocarboxylic acid that appears to be involved in the control of triacylglycerol synthesis.
|Stilbamidine is a diamidine and is used to treat various fungal infections.
|Scoparone, a natural product isolated and purified from the herbs of Artemisia scoparia, with antifungal, antianginal, antioxidant, immunosuppression and vasorelaxation effects, protects against carbon tetrachloride-induced liver injury, is a very efficient inhibitor of ultraviolet radiation -induced lipid peroxidation and damage, and a phytoalexin associated with resistance of citrus to Phytophthora citrophthora.
|Robinetin, a natural product isolated and purified from the leaves of Robinia pseudacacia, has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.
|Ravuconazole is an orally available triazoleantifungle agent that potently inhibits a wide range of fungi.
|Radicicol is an inhibitor of Hsp90 with an IC50 value of 1 μM. Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation. Radicicol is an antifungal antibiotic with antimalarial activity, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB.
|Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria.
|Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T.
|Pogostone is isolated from the herbs of pogostemon cablin which possesses potent anti-bacterial and anti-fungal activities.
|1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one 2-aminoethanol salt
|Piroctone olamine is a pyridine derivate. It is known to have a fungicidal effect.
|Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. It shows antifungal activity, anti-inflammatory activity and lower toxicity.
|Penthiopyrad is a carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps and inhibits fungal respiration by binding to mitochondrial respiratory complex II.
|Patchouli Alcohol is a naturally occuring sesquiterpene alcohol found in patchouli oil with antibacterial, antifungal, and antiviral properties.
|o-Veratraldehyde is used as the materials for the organic synthesis intermediates.
|Methyl trans-p-Coumarate is an atifungal agent and a cinnamic acid derivative.
|Licoisoflavone B, a natural product isolated and purified from the roots of Glycyrrhiza aspera, exhibits antimutagenic activity against carcinogenic N-methyl-N-nitrosourea (MNU), it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.
|Kumatakenin, a natural product isolated and purified from the roots of Astragalus membranaceus, has antibacterial and antifungal activities.
|Isodiospyrin, a natural product isolated and purified from the herbs of Diospyros morrisiana, exhibits remarkably good antifungal activity, the MIC values of the isodiospyrin was 5-160 μg/mL & the MFC values was 40-160 μg/mL.
|iKIX1 is an inhibitor of Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection.
|Hexaconazole inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, it is a broad-spectrum triazole fungicide.
|Hederagenin is a plant metabolite which can prevent fungal growth, bacterial growth, and viral plant diseases.
|Germacrene D is isolated from Bursera species. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles.
|Fosravuconazole L-lysine ethanolate
|Fosravuconazole L-lysine ethanolate (F-RVCZ) is a prodrug of ravuconazole, a novel triazole antifungal agent, exerting broad and potent antifungal activity.
|Fludazonium chloride is anti-fungal agent that can be used to treat systemic fungal infections.
|Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure.
|Ethylparaben, a natural product isolated and purified from the male melon fly Dacus cucurbitae, is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative.
|CsCl is considered to be the most toxic of the alkali chlorides, known to inhibit fungal growth.
|Chlormidazole hydrochloride is an antifungal agent and has inhibitory activity against many fungi and some gram-positive cocci. Chlormidazole hydrochloride can be applied in fungal and bacterial infections of nails and skin, including interdigital and periungual mycoses.
|Chlordantoin is antifungal drug that can be used for the treatment of vaginal candidiasis.
|Carboxin is an fungicide used in agriculture.
|Broxaldine is an antiprotozoal drug for the treatment of intestinal amoebiasis and childhood diarrhea.
|Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation.
|AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.
|Aliconazole is derivative of imidazole with antifungal activity.
|5-Hydroxymethylfurfural (5-HMF) is an important bio-sourced intermediate, formed from carbohydrates such as glucose or fructose and used for production of fuels and chemical intermediates.
|5-Dehydroepisterol is an episterol derivative and an intermediate in steroid biosynthesis. 5-Dehydroepisterol can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase. 5-Dehydroepisterol has anti-fungal activities.
|2'-hydroxygenistein, a natural product isolated and purified from the roots of Lupinus mutabilis with antifungal activity, exhibits greater antiproliferative effects in MCF-7 human breast cancer cells than does genistein, and shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B.