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Transferase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN12963 | Tipifarnib | 192185-72-1 | Tipifarnib is an inhibitor of farnesyltransferase with IC50 of 0.6 nM. |
| CSN16117 | 2-(((2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl)thio)benzoic acid | 162520-00-5 | Salirasib is an inhibitor of prenylated protein methyltransferase (PPMTase) with Ki of 2.6 μM and can inhibit the methylation of Ras. |
| CSN10813 | Perillyl alcohol | 536-59-4 | Perillyl Alcohol is a naturally occurring monocyclic terpene which can inhibit farnesyl transferase and geranylgeranyl transferase. |
| CSN11326 | Lonafarnib | 193275-84-2 | Lonafarnib is a FPTase inhibitor. It can inhibit H-ras (IC50 = 1.9 nM), K-ras-4B (IC50 = 5.2 nM) and N-ras (IC50 = 2.8 nM). |
| CSN18799 | LB42708 | 226929-39-1 | LB42708 is an orally active farnesyltransferase (FTase) inhibitor with IC50 of 0.8, 1.2, and 2.0 nM toward H-ras, N-ras, and K-ras, respectively. |
| CSN12834 | L-778123 HCl | 253863-00-2 | L-778123 HCl is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination. |
| CSN11092 | (E)-3,7-Dimethylocta-2,6-dien-1-ol | 106-24-1 | Geraniol is an inhibitor of glutathion S transferase with anticarcinogenic property. |
| CSN18001 | FTI-277 | 170006-73-2 | FTI-277 is an inhibitor of farnesyl transferase (FTase) and a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. |
| CSN18044 | FTI-277 HCl | 180977-34-8 | FTI-277 HCl is an inhibitor of farnesyl transferase (FTase) and a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. |
| CSN16273 | EPZ015666 | 1616391-65-1 | EPZ015666 is a selective inhibitor of PRMT5 with Ki of 5 nM. |
| CSN10363 | Azaserine | 115-02-6 | Azazerine is a competitive inhibitor of glutamine amidotransferase, a key enzyme responsible for glutamine metabolism. |
| CSN12803 | Etomoxir sodium salt | 828934-41-4 | (R)-(+)-etomoxir sodium salt is inhibitor of carnitine palmitoyltransferase I (CPT1) and can reduce β-oxidation in mitochondria. It shows inhibition of cardiolipin biosynthesis. |
