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Src

Src

货号 产品名 CAS号 信息
CSN12259 Saracatinib 379231-04-6 Saracatinib is Src inhibitor with IC50 of 2.7 nM.
CSN11759 1-(tert-Butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 172889-27-9 PP2 is a ATP-competitive inhibitor of the Src family of protein tyrosine kinases. The IC50s for p56lck, p59fynT, Hck, Src are 4 nM, 5 nM, 5 nM, 100 nM, respectively.
CSN11758 PP1 172889-26-8 PP1 is a selective inhibitor of Src and Lck/Fyn with IC50 of 5 nM, 6 nM, respectively.
CSN12857 PD173955 260415-63-2 PD173955 is an src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase and is less potent for FGFRα and no activity on InsR and PKC.
CSN11935 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile 380843-75-4 Bosutinib is an inhibitor of Src and Abl with IC50 of 1.2 nM and 1 nM.
CSN18508 A-770041 869748-10-7 A-770041 is selective and orally active Src-family Lck inhibitor and is a 147 nM inhibitor of Lck(1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.
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