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Sesquiterpenoids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN15519 | Vibralactone D | 1251748-32-9 | Vibralactones D is a natural product isolated and purified from cultures of the basidiomycete Boreostereum vibrans, showing weak inhibitory activities against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD) with IC(50) values of 85.7 mM (human HSD1), 295.2 mM (mouse HSD1), and 87.1 mM (human HSD2). |
| CSN14948 | Pterosin B | 34175-96-7 | Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. |
| CSN13095 | Pterodondiol | 60132-35-6 | Pterodondiol has moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus circulans. |
| CSN18699 | (3aS,9aR,10aR,10bS,E)-6,9a-Dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-one | 20554-84-1 | Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium) with multiple biological functions. Parthenolide inhibits the growth of the promastigote form of L. amazonensis with IC50 of 3.6 μg/mL, induces apoptosis in cancer cells and blocks inflammation by inhibiting signaling through NF-κB. |
| CSN11462 | Mollugin | 55481-88-4 | Mollugin, a natural product isolated and purified from the roots of Rubia cordifolia L., may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. |
| CSN19969 | Linderane | 13476-25-0 | Linderane, a natural product isolated and purified from the roots of Lindera aggregata( Sims) Kosterm, is an inactivator of CYP2C9. |
| CSN12309 | Isoalantolactone | 470-17-7 | Isoalantolactone is a naturally occuring sesquiterpene lactone isolated from Inula helenium with a role as an apoptosis inducer, an antifungal agent and a plant metabolite. |
| CSN16274 | Fraxinellone | 28808-62-0 | Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2+ channel, while dictamine relaxed the rat aorta by suppressing the Ca2+ influx through both voltage-dependent and receptor-operated Ca2+ channels, and can dramatically induce apoptosis of activated peripheral CD4(+) T cells in vivo, consequently resulting in less CD4(+) T-cell activation and infiltration to the liver. |
| CSN13554 | Eupalinolide B | 877822-41-8 | Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC. |
| CSN13554 | Eupalinolide B | 877822-41-8 | Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC. |
| CSN14137 | Curzerenone | 20493-56-5 | Curzerenone, a natural product isolated and purified from the rhizome of Curcuma zedoaria, has slightly effective against E. coli (IZ = 10.8 ± 0.52. Curzerenone and holds great promise for use in chemopreventive and chemotherapeutic strategies. |
| CSN16398 | (3aS,6E,10E,11aR)-6,10-Dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one | 553-21-9 | Costunolide shows anti-inflammatory and anti-oxidant activities and also induces apoptosis. It is a sesquiterpene lactone isolated from stem bark of Magnolia sieboldii, |
| CSN16181 | Carabrone | 1748-81-8 | Carabrone, a natural product isolated and purified from the herbs of Carpesium abrotanoides, exhibit antifungal activities in vitro or in vivo. |
| CSN13071 | 4-Oxo-4-(((3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic acid | 88495-63-0 | Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and EXP1 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro. |
| CSN50166 | 2-Benzyl-1-methyl-5-nonylpyrrolidin-3-ol | 119463-16-0 |
