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Sesquiterpenoids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN11893 | (Z)-2-Methyl-5-((1S,2R,4R)-2-methyl-3-methylenebicyclo[2.2.1]heptan-2-yl)pent-2-en-1-ol | 77-42-9 | β-Santalol is a compound of sandalwood oil showing antiinflammatory property by suppressing of lipopolysaccharide-stimulated cytokine/chemokine production in skin cells and anti-viral effect against influenza viral replication in vitro. |
| CSN17004 | alpha-Cyperone | 473-08-5 | α-Cyperone, a natural product isolated and purified from the hizomes of Cyperus rotundus L., is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation. |
| CSN13998 | Xanthatin | 26791-73-1 | Xanthatin, a natural product isolated and purified from the fruits of Xanthium sibiricum with cytotoxic, antibacterial and antifungal activities, can inhibit murine melanoma B16-F10 cell proliferation possibly associated with activation of Wnt/β-catenin pathway and its activity against melanoma tumor might also be relevant to inhibition of angiogenesis. |
| CSN14458 | Vomifoliol | 23526-45-6 | Vomifoliol, a natural product isolated and purified from the herbs of Vitis vinifera, can cause as much stomatal closure in epidermal strips of Eichhornia crassipes (Mart.) Solms as ABA at identical concentrations. |
| CSN14464 | Voleneol | 70389-88-7 | Voleneol, a natural product isolated and purified from the herbs of Curcuma wenyujin, can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells. it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), suggest thats DE may be a good candidate to regulate LPS-induced inflammatory response. |
| CSN13958 | Tussilagone | 104012-37-5 | Tussilagone, a natural product isolated and purified from the flower of Tussilago farfara, has potential treatment of neuro-inflammatory diseases through the inhibition of overproduction of nitric oxide and prostaglandin E(2) . |
| CSN13977 | Spathulenol | 6750-60-3 | Spathulenol, a natural product isolated and purified from the herbs of Salvia sclarea, has immunoinhibitory effect and shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway. |
| CSN14075 | Shyobunone | 21698-44-2 | Shyobunone, a natural product isolated and purified from the rhizomes of Acorus calamus L. with insecticidal and repellant activity, exhibits strong contact toxicity against Lasioderma serricorne (LS adults with LD50 values of 20.24 and 24.19 ug/adult, respectively and they are strongly repellent against Tribolium castaneum (TC) at 78.63 nL/cm2. |
| CSN14937 | Scabertopin | 185213-52-9 | Scabertopin, a natural product isolated and purified from the herbs of Elephantopus scaber Linn., exhibits significant antitumor effect in vitro in a concentration-dependent manner. |
| CSN14454 | Santamarine | 4290-13-5 | Santamarine, a natural product isolated and purified from the root of Dolomiaea souliei (Franch.) Shih, with significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine, and shows anti-bactericidal activity against clinical strains of Mycobacterium tuberculosis. |
| CSN14456 | (S)-4-Hydroxy-3,5,5-trimethyl-4-((R,E)-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-1-en-1-yl)cyclohex-2-en-1-one | 54835-70-0 | Roseoside is a natural product isolated and purified from the herbs of Catharanthus roseus, with inhibitory activity on leukotriene release from mouse bone marrow-derived cultured mast cells (BMCMC) and insulinotropic activity, enhancing insulin release from the β-cell line INS-1. |
| CSN14948 | Pterosin B | 34175-96-7 | Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. |
| CSN11658 | Patchouli alcohol | 5986-55-0 | Patchouli Alcohol is a naturally occuring sesquiterpene alcohol found in patchouli oil with antibacterial, antifungal, and antiviral properties. |
| CSN11611 | Onitin | 53823-02-2 | Onitin, a natural product isolated and purified from the herbs of Onychium japonicum, exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. |
| CSN11543 | Nerolidol | 7212-44-4 | Nerolidol, a natural product isolated and purified from the peel of Citrus maxima, shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. Nerolidol is mainly related to ROS and DNA single strand breaks generated by the presence of oxidative lesions. |
| CSN19880 | Nardosinone | 23720-80-1 | Nardosinone was isolated as an enhancer of nerve growth factor (NGF) from Nardostachys chinensis. Nardosinone (0.1-100 microM) enhanced dibutyryl cyclic AMP (dbcAMP, 0.3 mM)- and staurosporine (10 nM)-induced neurite outgrowth from PC12D cells in a concentration-dependent manner, suggesting that Nardosinone enhances a downstream step of MAP kinase in the MAP kinase-dependent signaling pathway. |
| CSN13549 | Lindenenol | 26146-27-0 | Linderene is a natural product isolated and purified from the roots of Lindera aggregata (Sims) Kosterm. |
| CSN13180 | Linderalactone | 728-61-0 | Linderalactone, a natural product isolated and purified from the roots of Lindera aggregata, shows significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC50 is 8.48 µg/mL. |
| CSN14465 | Kobusone | 24173-71-5 | Kobusone is a natural product isolated and purified from the roots of Cyperus rotundus L.. |
| CSN14461 | Isofuranodiene | 57566-47-9 | Isofuranodiene, a natural product isolated and purified from the herbs of Chloranthus spicatus, has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells, protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases and can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents. |
| CSN14457 | γ-Costic acid | 69978-82-1 | Isocostic acid is a natural product isolated and purified from the roots of Aucklandia lappa Decne.. |
| CSN14073 | Ilicic acid | 4586-68-9 | Ilicic acid is a natural product isolated and purified from the bark of Laggera pterodonta with anti-hyperglycemic and anti-inflammatory activities. |
| CSN13571 | Humulene oxide II | 19888-34-7 | Humulene epoxide II, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe, has mildly phytotoxic and antifungal activities. |
| CSN23313 | Guaiazulene | 489-84-9 | Guaiazulene is a derivative of azulene can be used as skin care products ingredients and volatile dye. |
| CSN16452 | Germacrone | 6902-91-6 | Germacrone, a natural product isolated and purified from the rhizoma of Curcuma wenyujin with anti-tumor activity, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway, and may be a potent chemopreventive drug candidate for liver cancer via regulating the expression of proteins related to G2/M cell cycle and apoptosis, and p53 and oxidative damage may play important roles in the inhibition of human hepatoma cells growth by germacrone. |
| CSN12303 | Dehydrocostus Lactone | 477-43-0 | Dehydrocostus Lactone a naturally occuring sesquiterpene lactone in the roots of Saussurea lappa with anti-inflammatory activity. |
| CSN16370 | (3S,3aS,5S,6R,8aS)-5-Isopropyl-3-methyl-8-methyleneoctahydro-6H-3a,6-epoxyazulen-6-ol | 4871-97-0 | Curcumol is a sesquiterpene originally isolated from curcuma rhizomes showing anticancer activities both in vitro and in vivo. |
| CSN14136 | Cryptomeridiol | 4666-84-6 | Cryptomeridiol, a natural product isolated and purified from the herbs of Blumea balsamifera DC, exhibits a significant and concentration-dependent inhibitory effect on platelet-activating factor receptor binding, and has low activity against A. |
| CSN14463 | Clovanediol | 2649-64-1 | Clovanediol is a natural product isolated and purified from the herbs of Psidium guajava. |
| CSN14698 | Brevilin A | 16503-32-5 | Brevilin A, a natural product isolated and purified from the herbs of Centipeda minima, is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STATs, and has antigiardial activity (IC50 = 16.1 μM) and was similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). |
| CSN14074 | Costic acid | 3650-43-9 | beta-Costic acid, a natural product isolated and purified from the herb of Dittrichia graveolens, is used against the acari Varroa destructor as parasite of the honey bee. |
| CSN13607 | (4aS,8aR)-3,8a-Dimethyl-5-methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan | 6989-21-5 | Atractylone, a natural product isolated and purified from the roots of Atractylodes macrocephala, has inhibitory effects on mast cell-mediated allergic reactions, it regulates the degranulation of mast cell, proves its potential in the treatment of mast cell-mediated allergic reactions. |
| CSN18461 | Arglabin | 84692-91-1 | Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella and an anticancer natural compound. |
| CSN14459 | Alismol | 87827-55-2 | Alismol, a natural product isolated and purified from the tubers of Alisma plantago-aquatica Linn., acts primarily on nerve terminals and inhibits their responses to electrical stimulation by interfering with NAd release, inhibits mainly Ca2+ influx through a voltage-dependent Ca2+ channel, holds great promise for use in chemopreventive and chemotherapeutic strategies. |
| CSN16394 | (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one | 546-43-0 | Alantolactone is a sesquiterpene lactone with potential activity against triple-negative breast cancer MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3) signaling pathway. |
| CSN12310 | (2Z,4E)-5-((S)-1-Hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid | 21293-29-8 | Abscisic Acid is a plant hormone with functions in many plant developmental processes, including seed and bud dormancy, the control of organ size and stomatal closure. |
| CSN13389 | 1β-Hydroxy-4(15),5E,10(14)-germacratriene | 81968-62-9 | 4(15),5,10(14)-Germacratrien-1-ol is a natural product isolated and purified from the roots of Acorus calamus L.. |
| CSN13027 | 3,4-Dihydro-2,2-Dimethyl-2H-Naphtho[1,2-B]pyran | 16274-33-2 | 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran is a natural product isolated and purified from the herbs of Catalpa ovata. |
| CSN13248 | 1-Hydroxy-2-prenylnaphthalene | 16274-34-3 | 1-Hydroxy-2-prenylnaphthalene is a natural product isolated and purified from the herbs of Catalpa ovata. |
| CSN13290 | 1,10:4,5-Diepoxy-7(11)-germacren-8-one | 32179-18-3 | 1,10:4,5-Diepoxy-7(11)-germacren-8-one is a natural product isolated and purified from the herbs of Isodon adenantha. |
