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Prostaglandin Receptor

Prostaglandin Receptor

货号 产品名 CAS号 信息
CSN12127 Travoprost 157283-68-6 Travoprost is a synthetic prostaglandin F analog as a potent and selective FP prostaglandin receptor agonist, used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure.
CSN16883 Setipiprant 866460-33-5 Setipiprant is an orally available, selective CRTH2 antagonist.
CSN11791 Prostaglandin E2 363-24-6 Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor.
CSN13785 PF-04418948 1078166-57-0 PF-04418948 is an antagonist of prostaglandin EP2 receptor with IC50 of 16 nM.
CSN13430 Timapiprant 851723-84-7 OC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist with IC50 of 13 nM.
CSN16825 Selexipag 475086-01-2 NS-304 is an agonist of prostacyclin IP1 receptor with Ki of 260 nM. It is used for the treatment of pulmonary arterial hypertension.
CSN16760 2-(4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetic acid 475085-57-5 MRE-269 can act as an agonist of IP receptor and it is an active metabolite of selexipag.
CSN16851 rel-Methyl 7-((1R,2R,3R)-3-hydroxy-2-((E)-4-hydroxy-4-methyloct-1-en-1-yl)-5-oxocyclopentyl)heptanoate 59122-46-2 Misoprostol is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.
CSN16233 MF498 915191-42-3 MF498 is a selective E prostanoid receptor 4 (EP4 receptor) antagonist, displayed strong binding affinity for the EP4 receptor with Ki of 0.7 nM.
CSN11301 Limaprost 74397-12-9 Limaprost is a PGE1 analog and potent platelet adhesion inhibitor.
CSN11189 Iloprost 78919-13-8 Iloprost is a synthetic analogue of prostacyclin PGI2.
CSN10940 Ethamsylate 2624-44-4 Ethamsylate acts as a haemostatic drug by increasing capillary endothelial resistance and promoting platelet adhesion.
CSN10910 Enprostil 73121-56-9 Enprostil is a synthetic prostaglandin designed to resemble dinoprostone.
CSN21111 Palupiprant 1369489-71-3 E7046 is a specific antagonist of the type 4 prostaglandin E2 (PGE2) receptor EP4. It possesses significant antitumor growth activity in multiple preclinical tumor models through modulating myeloid cells, including tumor-associated macrophages and myeloid-derived suppressor cells.
CSN11793 Dinoprost tromethamine salt 38562-01-5 Dinoprost tromethamine is a natural prostaglandin used as an abortifacient.
CSN11792 Dinoprost 551-11-1 Dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
CSN13150 CJ-42794 847728-01-2 CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3).
CSN17217 (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-N-ethylhept-5-enamide 155206-00-1 Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension.
CSN17196 AH 6809 33458-93-4 AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors.
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