400-920-2911 sales@csnpharm.cn
Prostaglandin Receptor
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN12127 | Travoprost | 157283-68-6 | Travoprost is a synthetic prostaglandin F2α analog as a potent and selective FP prostaglandin receptor agonist, used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. |
CSN16883 | Setipiprant | 866460-33-5 | Setipiprant is an orally available, selective CRTH2 antagonist. |
CSN11791 | Prostaglandin E2 | 363-24-6 | Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor. |
CSN13785 | PF-04418948 | 1078166-57-0 | PF-04418948 is an antagonist of prostaglandin EP2 receptor with IC50 of 16 nM. |
CSN13430 | Timapiprant | 851723-84-7 | OC000459 is a potent and selective D prostanoid receptor 2 (DP2) antagonist with IC50 of 13 nM. |
CSN16825 | Selexipag | 475086-01-2 | NS-304 is an agonist of prostacyclin IP1 receptor with Ki of 260 nM. It is used for the treatment of pulmonary arterial hypertension. |
CSN16760 | 2-(4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetic acid | 475085-57-5 | MRE-269 can act as an agonist of IP receptor and it is an active metabolite of selexipag. |
CSN16851 | rel-Methyl 7-((1R,2R,3R)-3-hydroxy-2-((E)-4-hydroxy-4-methyloct-1-en-1-yl)-5-oxocyclopentyl)heptanoate | 59122-46-2 | Misoprostol is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion. |
CSN16233 | MF498 | 915191-42-3 | MF498 is a selective E prostanoid receptor 4 (EP4 receptor) antagonist, displayed strong binding affinity for the EP4 receptor with Ki of 0.7 nM. |
CSN11301 | Limaprost | 74397-12-9 | Limaprost is a PGE1 analog and potent platelet adhesion inhibitor. |
CSN11189 | Iloprost | 78919-13-8 | Iloprost is a synthetic analogue of prostacyclin PGI2. |
CSN10940 | Ethamsylate | 2624-44-4 | Ethamsylate acts as a haemostatic drug by increasing capillary endothelial resistance and promoting platelet adhesion. |
CSN10910 | Enprostil | 73121-56-9 | Enprostil is a synthetic prostaglandin designed to resemble dinoprostone. |
CSN21111 | Palupiprant | 1369489-71-3 | E7046 is a specific antagonist of the type 4 prostaglandin E2 (PGE2) receptor EP4. It possesses significant antitumor growth activity in multiple preclinical tumor models through modulating myeloid cells, including tumor-associated macrophages and myeloid-derived suppressor cells. |
CSN11793 | Dinoprost tromethamine salt | 38562-01-5 | Dinoprost tromethamine is a natural prostaglandin used as an abortifacient. |
CSN11792 | Dinoprost | 551-11-1 | Dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. |
CSN13150 | CJ-42794 | 847728-01-2 | CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). |
CSN17217 | (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-N-ethylhept-5-enamide | 155206-00-1 | Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension. |
CSN17196 | AH 6809 | 33458-93-4 | AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors. |