CAS No.: 34444-37-6
Nortrachelogenin Catalog No. CSN13651
Synonyms: (-)-Wikstromol
Nortrachelogenin, a natural product isolated and purified from the herbs of Trachelospermum jasminoides, shows effects on the central nervous system producing depression in rabbits and is an agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors (GFRs), thereby efficiently synergizing with TRAIL exposure.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Peuhu E, Paul P, et al. The antitumor lignan Nortrachelogenin sensitizes prostate cancer cells to TRAIL-induced cell death by inhibition of the Akt pathway and growth factor signaling. Biochem Pharmacol. 2013 Sep 1;86(5):571-83.
- [2] Kato A, Hashimoto Y, Kidokoro M. (+)-Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica. J Nat Prod. 1979 Mar-Apr;42(2):159-62.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 34444-37-6 | 储存条件 |
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| 分子式 | C20H22O7 | 运输 | 蓝冰 | |
| 分子量 | 374.38 | 别名 | (-)-Wikstromol |
