55-97-0|Hexamethonium Bromide|CsnPharm

CAS No.: 55-97-0

Hexamethonium Bromide/六甲溴铵 Catalog No. CSN11146

Synonyms: Hexamethonium (bromide);Hexamethionium bromide;Esametina

Hexamethonium bromide is a nicotinic cholinergic antagonist as the prototypical ganglionic blocker.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Hexamethonium Bromide is effective against Ach and carbachol (CCh) on the amplitude of endplate responses of rat omohyoid muscle with EC50 of 300 μM and 100 μM, respectively. Hexamethonium Bromide is also a weak inhibitor of acetylcholinesterase activity in rat muscle homogenates with EC50 of 1.5 mM^[3]. At low frequencies of stimulation (0.5-2 Hz), hexamethonium (200 mM) and methyllycaconitine (2.0 mM) increased e.p.c. quantal content by 30-40%. The low frequency augmentation of e.p.c. quantal content by hexamethonium was absent when extracellular [Ca²⁺] was lowered from 2.0 to 0.5 mM^[4].
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03360136	Exhaustion; Syndrome ... more >> Burnout, Professional Burnout Syndrome Adjustment Disorders Collapse <<	Not Applicable	Recruiting	July 1, 2020	Sweden ... more >> PBM Sweden AB Globen Recruiting Stockholm, Södermanland, Sweden, 12177 Contact: Gunilla Brodda Jansen, Assoc. Proff. 070-716 39 13 ext +46 gunillabroddajansen@pbm.se PBM Sweden City Recruiting Stockholm, Uppland, Sweden, 114 47 Contact: Gunilla Brodda Jansen, Assoc. Proff. 070-716 39 13 ext +46 gunillabroddajansen@pbm.se Collapse <<
NCT03468114	Enteric Infections ... more >> Diarrhea Collapse <<	Not Applicable	Recruiting	December 2018	Kenya ... more >> Great Lakes University Kisumu Recruiting Kisumu, Kenya Contact: Sheillah Simiyu, PhD +254 722 215291 sheillahshie@gmail.com Collapse <<
NCT01626703	Depression Sc... more >>reening Elderly Collapse <<	Not Applicable	Completed	-	Korea, Republic of ... more >> Chungju community health care center Chungju, Choongbuk, Korea, Republic of, 123456 Collapse <<

更多
参考文献

[1] Tian L, Prior C, et al. Hexamethonium- and methyllycaconitine-induced changes in acetylcholine release from rat motor nerve terminals. Br J Pharmacol. 1997 Nov;122(6):1025-34.
[2] Rang HP, Rylett RJ. The interaction between hexamethonium and tubocurarine on the rat neuromuscular junction. Br J Pharmacol. 1984 Mar;81(3):519-31.
[3] Rang HP, Rylett RJ. The interaction between hexamethonium and tubocurarine on the rat neuromuscular junction. Br J Pharmacol. 1984 Mar;81(3):519-31.
[4] Tian L, Prior C, Dempster J, Marshall IG. Hexamethonium- and methyllycaconitine-induced changes in acetylcholine release from rat motor nerve terminals. Br J Pharmacol. 1997 Nov;122(6):1025-34.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.7610 mL
- 13.8050 mL
- 27.6100 mL
- 5 mM
- 0.5522 mL
- 2.7610 mL
- 5.5220 mL
- 10 mM
- 0.2761 mL
- 1.3805 mL
- 2.7610 mL

技术信息

CAS号

55-97-0

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C12H30Br2N2

运输

蓝冰

分子量

362.19

别名

Hexamethonium (bromide);Hexamethionium bromide;Esametina;Simpatoblock;Vegolysen;六甲溴铵

溶解度

DMSO	insoluble
Water	160.0 mg/mL (441.8 mM)

动物实验配方

0.5% CMC-Na

100 mg/mL

clear

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03360136	Exhaustion; Syndrome ... more >> Burnout, Professional Burnout Syndrome Adjustment Disorders Collapse <<	Not Applicable	Recruiting	July 1, 2020	Sweden ... more >> PBM Sweden AB Globen Recruiting Stockholm, Södermanland, Sweden, 12177 Contact: Gunilla Brodda Jansen, Assoc. Proff. 070-716 39 13 ext +46 gunillabroddajansen@pbm.se PBM Sweden City Recruiting Stockholm, Uppland, Sweden, 114 47 Contact: Gunilla Brodda Jansen, Assoc. Proff. 070-716 39 13 ext +46 gunillabroddajansen@pbm.se Collapse <<
NCT03468114	Enteric Infections ... more >> Diarrhea Collapse <<	Not Applicable	Recruiting	December 2018	Kenya ... more >> Great Lakes University Kisumu Recruiting Kisumu, Kenya Contact: Sheillah Simiyu, PhD +254 722 215291 sheillahshie@gmail.com Collapse <<
NCT01626703	Depression Sc... more >>reening Elderly Collapse <<	Not Applicable	Completed	-	Korea, Republic of ... more >> Chungju community health care center Chungju, Choongbuk, Korea, Republic of, 123456 Collapse <<
NCT02053649	Depression Ma... more >>jor Depressive Disorder Postpartum Depression Collapse <<	Not Applicable	Recruiting	-	United States, Rhode Island ... more >> Miriam Hospital Women's Medicine Collaborative Recruiting Providence, Rhode Island, United States, 02904 Sub-Investigator: Teri Pearlstein, MD Collapse <<
NCT01945814	EBV CMV ... more >> Adenovirus Collapse <<	Phase 1	Recruiting	September 2020	United States, District of Col... more >>umbia Childrens National Medical Center Recruiting Washington, District of Columbia, United States, 20010 Contact: Fahmida Hoq, MBBS, MS 202-476-3634 fhoq@cnmc.org Collapse <<
NCT03180216	Viral Infections ... more >> Bone Marrow Transplant Infection Collapse <<	Phase 1	Recruiting	August 2021	United States, District of Col... more >>umbia Childrens National Medical Center Recruiting Washington, District of Columbia, United States, 20010 Contact: Fahmida Hoq, MBBS, MS 202-476-3634 fhoq@cnmc.org Contact: Catherine Bollard, MD 202-476-4776 Collapse <<

Hexamethonium Bromide/六甲溴铵 Catalog No. CSN11146

靶点选择性

请登录您的专属账户

确认信息