CAS No.: 147859-80-1
CA-074 methyl ester Catalog No. CSN16115
Synonyms: CA-074Me;Cathepsin B Inhibitor IV
CA-074 Methyl Ester is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
动物研究 剂量 Mice: 10 mg/kg[3] (i.v.)
给药途径 i.v.
- 参考文献
- [1] Towatari T, Nikawa T, et al. Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo. FEBS Lett. 1991 Mar 25;280(2):311-5.
- [2] Withana NP, Blum G, et al. Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Res. 2012 Mar 1;72(5):1199-209.
- [3] Towatari T, Nikawa T, Murata M, Yokoo C, Tamai M, Hanada K, Katunuma N. Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo. FEBS Lett. 1991 Mar 25;280(2):311-5. doi: 10.1016/0014-5793(91)80319-x. PMID: 2013329.
- [4] Withana NP, Blum G, Sameni M, Slaney C, Anbalagan A, Olive MB, Bidwell BN, Edgington L, Wang L, Moin K, Sloane BF, Anderson RL, Bogyo MS, Parker BS. Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Res. 2012 Mar 1;72(5):1199-209. doi: 10.1158/0008-5472.CAN-11-2759. Epub 2012 Jan 19. PMID: 22266111; PMCID: PMC3538126.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 147859-80-1 | 储存条件 |
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| 分子式 | C19H31N3O6 | 运输 | 蓝冰 | |||||
| 分子量 | 397.47 | 别名 | CA-074Me;Cathepsin B Inhibitor IV | |||||
| 溶解度 |
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动物实验配方 |
