CAS No.: 102052-95-9
3-Deazaneplanocin A/3-去氮腺嘌呤A Catalog No. CSN17152
Synonyms: DZNep;3-Deazaneplanocin;NSC 617989
3-Deazaneplanocin A is an attractive epigenetic anticancer agent through the inhibition of the cellular enhancer of zeste homolog 2 (EZH2) protein.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Avan A, Crea F, et al. Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells. Mol Cancer Ther. 2012 Aug;11(8):1735-46.
- [2] Fiskus W, Wang Y, et al. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells. Blood. 2009 Sep 24;114(13):2733-43.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 102052-95-9 | 储存条件 |
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| 分子式 | C12H14N4O3 | 运输 | 蓝冰 | |
| 分子量 | 262.26 | 别名 | DZNep;3-Deazaneplanocin;NSC 617989;3-去氮腺嘌呤A |
