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Phenols

Phenols

货号 产品名 CAS号 信息
CSN10043 (rel)-β-Tocopherol 148-03-8 β-tocopherol is one of the naturally occurring forms of Vitamin E and is biologically less active than α-Tocopherol.
CSN15878 Urolithin B 1139-83-9 Urolithin B is a natural product with anti-proliferative and antioxidant activity, which can penetrate the blood-brain barrier and may have neuroprotective effects against Alzheimer’s Disease.It inhibits aromatase activity in human placental microsomes and aromatase-sensitive MCF-7 (MCF-7aro) human breast cancer cells when used at concentrations of 47 and 4.7 µM, respectively.
CSN14417 Torachrysone 22649-04-3 Torachrysone, a natural product isolated and purified from the seeds of Cassia obtusifolia, shows promising antioxidant activity and noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2-64 mg/mL.
CSN13133 2-Isopropyl-5-methylphenol 89-83-8 Thymol, a natural product isolated and purified from the herbs of Thymus serpyllum L., is a positive allosteric modulator of human GABAA receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster.
CSN17210 (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-hydroxyphenethoxy)tetrahydro-2H-pyran-3,4,5-triol 10338-51-9 Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata.
CSN16007 Punicalagin 65995-63-3 Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T.
CSN19413 (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol   27208-80-6 Polydatin, extracted from the roots ofPolygonum cuspidatumSieb, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models.
CSN15473 Perilloxin 263249-77-0 Perilloxin, a natural product isolated and purified from the stems of Perilla frutescens var. acuta., possesses inhibitory activities against cyclooxygenase-1,with IC(50) values of 23.2 mM.
CSN18175 Paradol 27113-22-0 Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site, it's a pungent phenolic substance isolated and purified from ginger and other Zingiberaceae plants.
CSN19396 (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid 24280-93-1 Mycophenolic Acid is an an immunosuppresant agent with a potent inibition of IMPDH (inosine monophosphate dehydrogenase) and potent anti-proliferative activity, it can be isolated from several Penicillium species.
CSN15165 Mulberrofuran H 89199-99-5 Mulberrofuran H exhibits potent antifungal activity against phytopathogenic fungi Colletotrichum orbiculare, Phytophthora capsici, Corynespora cassiicola and Fusarium oxysporum.
CSN14672 Moracin P 102841-46-3 Moracin P, a natural product isolated and purified from the root bark of Morus alba L., shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells, exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia, and might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells.
CSN15161 Moracin C 69120-06-5 Moracin C, a natural product isolated and purified from the root bark of Morus alba L., is a potent antibacterial compound which inhibits FabI and fatty acid synthesis.
CSN12887 Methyl 2,4-dihydroxy-6-methylbenzoate 3187-58-4 Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM.
CSN12887 Methyl 2,4-dihydroxy-6-methylbenzoate 3187-58-4 Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM.
CSN12840 3-Hydroxy-4-Methoxybenzaldehyde 621-59-0 Isovanicaline, a natural product isolated and purified from the barks of Pinus yunnanensis, is a selective inhibitor of aldehyde oxidase, is metabolized by aldehyde dehydrogenase into isovanillic acid ,and the LD50 (rat, ipr) is 1276 mg/kg.
CSN14412 Hirsutenone 41137-87-5 Hirsutenone, a natural product isolated and purified from the eaves of Alnus nepalensis, exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2, attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity, and may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone showed potent PL(pro) inhibitory activity with IC50 value of 4.1µM.
CSN20010 2-Hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-one 499-44-5 Hinokitiol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. It can partially mimic the function of missing protein transporters of iron, and possibly other ions, may have potential in treating human diseases.
CSN16502 Guaiacol 90-05-1 Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes.
CSN11097 Ginkgolic Acid 22910-60-7 Ginkgolic acid is a natural product isolated and purified from the leaves of Ginkgo biloba L.with suspected cytotoxic, allergenic, mutagenic and carcinogenic properties.
CSN11098 Ginkgolic Acid (C13:0) 20261-38-5 Ginkgolic Acid C13:0 is a natural product with wide antimicrobial spectrum.
CSN17019 2,5-Dihydroxybenzoic Acid 490-79-9 Gentisic acid is a natural product isolated and purified from the roots of Gentiana scabra Bunge.
CSN15170 Gancaonin I 126716-36-7 Gancaonin I is a natural product isolated and purified from the roots of Glycyrrhiza glabra with anti-BsFtsZ GTPase activities and significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.
CSN15859 Ethyl 4-hydroxybenzoate 120-47-8 Ethylparaben, a natural product isolated and purified from the male melon fly Dacus cucurbitae, is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative.
CSN16055 Ethyl 2,4,6-Trihydroxybenzoate 90536-74-6 Ethyl 2,4,6-trihydroxybenzoate, a natural product isolated and purified from the herbs of Celtis biondii, suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes, and is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells.
CSN15159 Ducheside A 176665-78-4 Ducheside A has anti-fungal activity.
CSN19341 Desoxyrhaponticin 30197-14-9 Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CSN19341 Desoxyrhaponticin 30197-14-9 Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CSN20998 Dehydropachymic acid 77012-31-8 Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity.
CSN20998 Dehydropachymic acid 77012-31-8 Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity.
CSN20998 Dehydropachymic acid 77012-31-8 Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity.
CSN20998 Dehydropachymic acid 77012-31-8 Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity.
CSN19424 (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione 458-37-7 Curcumin is a natural phenolic compound with impressive antioxidant properties.
CSN16343 2,4,5-Trimethoxybenzaldehyde 4460-86-0 Asaronaldehyde is a COX-2 inhibitor, exhibiting 17-fold selectivity over COX-1, it's a natural product isolated and purified from the rhizoma of Acorus tatarinowii Schott.
CSN20557 Artepillin C 72944-19-5 Artepillin C is a major, biologically active ingredient of Brazilian propolis, possesses anticancer activity against several cancer cells with different tissue origins.
CSN19347 Alternariol 641-38-3 Alternariol is a mycotoxin, topoisomerase I and II inhibitor and potential ER agonist found in Alternaria.
CSN14397 α-Viniferin 62218-13-7 alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
CSN19942 Agrimol B 55576-66-4 Agrimol B is a natural product isolated and purified from the herbs of Agrimonia pilosa Ledeb.
CSN19939 [8]-Shogaol 36700-45-5 8-Shogaol, a natural product isolated and purified from the rhizomes of Zingber officinale Rosc., can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells.
CSN19518 4-Hydroxybenzoic acid 99-96-7 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties.
CSN15174 4'-Hydroxy-2-O-methylanigorufone 204134-70-3 4'Hydroxy-2-O-methylanigorufone is a natural phytoalexin isolated and purified from the peels of unripe Musa acuminata [AAA] cv. Buñgulan fruit showing a strong α-glucosidase inhibitory effect.
CSN19517 4'-Hydroxyacetophenone 99-93-4 4'-Hydroxyacetophenone, a natural product isolated and purified from the herbs of Rhodiola crenulata, is a potent xanthine oxidase inhibitor.
CSN18711 3,4-Dimethoxybenzoic acid 93-07-2 3,4-Dimethoxybenzoic acid is a natural product isolated and purified from the fruits of Phyllanthus emblica L..
CSN22068 2-Ethyl-5-methylphenol 1687-61-2 2-Ethyl-5-methylphenol is a constituent of Angelica species, it is a metabolite of Penicillium species on barley.
CSN17071 2-(3,4-Dihydroxyphenyl)ethanol 10597-60-1 2-(3,4-Dihydroxyphenyl)ethanol is a potent and specific inhibitor of lipoxygenase activities, inhibits platelet 12-LO activity with IC50 of 4.2 mM and PMNL 5-LO activity with IC50 of 13 mM. It's a natural product isolated and purified from the herbs of Canarium album with antioxidant property.
CSN29062 Aristolochic acid D 17413-38-6
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