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NF-κB
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN12011 | Sulfasalazine | 599-79-1 | Sulfasalazine is a potent and specific NF-κB inhibitor and also inhibits system Xc and induces ferroptosis. |
| CSN16392 | Sodium 2-hydroxybenzoate | 54-21-7 | Sodium Salicylate is anti-inflammatory drugs which can inhibit the activation of NF-kappa B. |
| CSN19187 | SC75741 | 913822-46-5 | SC75741 is a novel NF-kappaB inhibitor. |
| CSN18699 | (3aS,9aR,10aR,10bS,E)-6,9a-Dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-one | 20554-84-1 | Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium) with multiple biological functions. Parthenolide inhibits the growth of the promastigote form of L. amazonensis with IC50 of 3.6 μg/mL, induces apoptosis in cancer cells and blocks inflammation by inhibiting signaling through NF-κB. |
| CSN11532 | Neferine | 2292-16-2 | Neferine, is a major alkaloid present in the green embryos of Nelumbo nucifera Gaertn with anti-arrhythmia, anti-hypertensive and vaso-relaxant properties , and is also a NF-κB inhibitor. |
| CSN12446 | 5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol | 528-43-8 | Magnolol is a multifunctional compound isolated from the Chinese medicinal plant Magnolia officinalis, with antifungal, antibacterial and antioxidant effects, as well as anti-inflammatory activity by interferring with NF-κB signaling and inhibiting IL-6-induced STAT3 activation. |
| CSN12507 | (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid | 1200-22-2 | Lipoic Acid can inhibit TNF-alpha-induced NF-kappaB activation. |
| CSN16019 | JSH-23 | 749886-87-1 | JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM in RAW 264.7 cell line. |
| CSN10802 | Diethyl (Z)-2-butenedioate | 141-05-9 | Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NFkB. |
| CSN18398 | Didox | 69839-83-4 | Didox can prevent LPS-induced NF-KB activation and translocation of NF-kappa beta p65 subunits. |
| CSN10751 | Dauricine | 524-17-4 | Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid. |
| CSN15792 | CID-2858522 | 758679-97-9 | CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 μM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways. |
| CSN10538 | Phenethyl caffeate | 104594-70-9 | Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
| CSN17286 | Ammonium pyrrolidine-1-carbodithioate | 5108-96-3 | Ammonium pyrrolidine-1-carbodithioate is a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction. |
| CSN18157 | Adjudin | 252025-52-8 | Adjudin exhibits anti-inflammatory properties by suppression of NF-κB p65 nuclear translocation and DNA binding activity as well as ERK MAPK phosphorylation. |
| CSN17995 | Adelmidrol | 1675-66-7 | Adelmidrol is an ethanolamide derivative of azelaic acid with anti-inflammatory properties partly dependent on PPARγ, it also markedly reduce pro-inflammatory NF-κB pathway. |
| CSN13425 | (-)-DHMEQ | 287194-40-5 | (-)-DHMEQ, the eutomer of DHMEQ , is a developed NF-kB inhibitor with stronger activity than (+)-DHMEQ., inhibits nuclear factor kB activation with IC50 value of 20 ug/mL. |
| CSN19066 | (+)-DHMEQ | 287194-41-6 | (+)-DHMEQ, the distomer of DHMEQ, is an inhibitor of NF-κB. |
