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Lignans

Lignans

货号 产品名 CAS号 信息
CSN14378 Yangambin 13060-14-5 Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role.
CSN14378 Yangambin 13060-14-5 Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role.
CSN19977 tracheloside 33464-71-0 Tracheloside, a natural product isolated and purified from the herbs of Trachelospermum jasminoides (Lindl.) Lem., significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC50 value of 0.31 mg/mL, a level of inhibition comparable to that of tamoxifen (IC50 = 0.43 mg/mL).
CSN11910 Secoisolariciresinol 29388-59-8 Secoisolariciresinol, a natural product isolated and purified from the Heartwood of Podocarpus spicata, exerts a suppressive effect on the gain of body weight of mice fed a high-fat diet by inducing gene expression of adiponectin, resulting in the altered expression of various genes related to the synthesis and β-oxidation of fatty acids.
CSN16630 (5S,6S,7S)-6-Hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-5-yl benzoate 58546-56-8 Schisantherin A is a natural product isolated and purified from the herbs of Chelidonium majus with anti-microbial, anti-oxidant and anti-inflammatory properties, and is a specific inhibitor of Rac1b.
CSN21036 Schisandrone 98619-25-1 Schisandrone is extracted from the fruits of schisandra sphenanthera.
CSN16433 (6R,7S,12aR)-5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene 61281-38-7 Schisandrin A is a naturally occuring agonist of the adiponectin receptor 2 with an IC50 value of 3.5 µM.
CSN12497 (R)-2-(((2S,3S)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid 121521-90-2 Salvianolic Acid B is a naturally occuring antioxidant and free radical scavenger from Salvia miltiorrhiza.
CSN12281 Pinoresinol 487-36-5 Pinoresinol, a natural product isolated and purified from the bark of Eucommia ulmoides Oliver, may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.
CSN15574 (2S,3R,4S,5S,6R)-2-(4-((1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)-3-methoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 487-41-2 Phillyrin is a naturally occuring AMPK activity enhancer, isolated and purified from the fruits of Forsythia suspensa.
CSN13651 Nortrachelogenin 34444-37-6 Nortrachelogenin, a natural product isolated and purified from the herbs of Trachelospermum jasminoides, shows effects on the central nervous system producing depression in rabbits and is an agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors (GFRs), thereby efficiently synergizing with TRAIL exposure.
CSN14342 Niranthin 50656-77-4 Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites.
CSN14342 Niranthin 50656-77-4 Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites.
CSN12446 5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol 528-43-8 Magnolol is a multifunctional compound isolated from the Chinese medicinal plant Magnolia officinalis, with antifungal, antibacterial and antioxidant effects, as well as anti-inflammatory activity by interferring with NF-κB signaling and inhibiting IL-6-induced STAT3 activation.
CSN11353 (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan 31008-18-1 Magnolin, a natural product isolated and purified from the flowers of Magnolia biondii Pamp., reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro.
CSN14375 Gomisin J 66280-25-9 Gomisin J is a natural product isolated and purified from the fruits of Schizandra chinensis with vasodilatory activity that mediates mainly by calcium-dependent activation of eNOS with subsequent production of endothelial NO, and inhibits LPO in rat liver mitochondria and protects cultured myocardial cells from being injured by calcium paradox.
CSN11112 (6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol 58546-54-6 Gomisin A is a major dibenzocyclooctadiene lignan from medicinal plant Schizandra Chinese, exhibiting hepatoprotective, antiviral, anticancer, neuroprotective and anti-inflammatory activity.
CSN14353 Deoxypodophyllotoxin 19186-35-7 Deoxypodophyllotoxin, a natural microtube inhibitor isolated and purified from the roots of Dysosma versipellis (Hance) M.Cheng ex Ying, is cytotoxic agent, antineoplastic agent and potent antitumor agent and may be beneficial in regulating the immediate-type allergic reaction.
CSN19920 Dehydrodiisoeugenol 2680-81-1 Dehydrodiisoeugenol, a natural product isolated and purified from the seeds of Myristica fragrans Houtt.
CSN19920 Dehydrodiisoeugenol 2680-81-1 Dehydrodiisoeugenol, a natural product isolated and purified from the seeds of Myristica fragrans Houtt.
CSN19867 L-asarinin 133-05-1 Asarinin, a natural product isolated and purified from the herbs of Asarum sieboldii Miq.
CSN12574 Arctiin 20362-31-6 Arctiin is a suppressor of cyclin D1 protein expression in multiple types of human tumor cells and also shows antiviral activity against influenza A.
CSN14120 Angeloylgomisin H 66056-22-2 Angeloylgomisin H, a natural product isolated and purified from the fruits of Schizandra chinensis, shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines and may present significant myocardial protective activity.
CSN21019 4-O-Methyl honokiol 68592-15-4 4-O-Methyl honokiol is a natural neolignan isolated from magnolia officinalis which acts as a PPARγ agonist and inhibtis NF-κB activity. It is used for cancer and inflammation research.
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