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RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis. Specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes.
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN33245 | FTO-IN-7 | 2243736-37-8 | MUN36378 is a FTO inhibitor for treatment of leukemia, extractd from patent WO 2018157842. |
CSN26121 | FB23-2 | 2243736-45-8 | FB23-2 is a FTO inhibitor. It directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. |
CSN62470 | FTO-IN-1 | 2243944-92-3 |
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