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Flavonoids

Flavonoids

货号 产品名 CAS号 信息
CSN10425 Wogonoside 51059-44-0 Wogonoside is a natural product isolated and purified from the herbs of Scutellaria baicalensis Georgi.
CSN19930 8-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 76135-82-5 Vitexin-4″-O-Glucoside can inhibit TPO activity. It is a natural product isolated and purified from the fruit of Crataegus pinnatifida Bge.
CSN14055 Velutin 25739-41-7 Velutin, a natural product isolated and purified from the leaves of Vernonia flexuosa with anti-inflammatory property, exhibits the greatest potency among all flavones in reducing TNF-α and IL-6 production and shows the strongest inhibitory effect in nuclear factor (NF)-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK phosphorylation.
CSN14055 Velutin 25739-41-7 Velutin, a natural product isolated and purified from the leaves of Vernonia flexuosa with anti-inflammatory property, exhibits the greatest potency among all flavones in reducing TNF-α and IL-6 production and shows the strongest inhibitory effect in nuclear factor (NF)-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK phosphorylation.
CSN19343 Tricin 520-32-1 Tricin, a natural product isolated and purified from the herb of Avena sativa, is evaluated as a type of tyrosinase inhibitor, exerts anti-inflammatory effect via a mechanism involving the TLR4/NF-κB/STAT signaling cascade, may be beneficial in HSC-targeting therapeutic or chemopreventive applications for hepatic fibrosis, and is with potential anti-HCMV activity and that CXCL11 is one of the chemokines involved in HCMV replication.
CSN19343 Tricin 520-32-1 Tricin, a natural product isolated and purified from the herb of Avena sativa, is evaluated as a type of tyrosinase inhibitor, exerts anti-inflammatory effect via a mechanism involving the TLR4/NF-κB/STAT signaling cascade, may be beneficial in HSC-targeting therapeutic or chemopreventive applications for hepatic fibrosis, and is with potential anti-HCMV activity and that CXCL11 is one of the chemokines involved in HCMV replication.
CSN19967 Silicristin 33889-69-9 Silychristin, a natural product isolated and purified from the herbs of Silybum marianum (L.) Gaertn., is a plant growth regulator, an anti-hepatotoxic agent, and an inhibitor of horseradish peroxidases and lipoxygenase.
CSN19979 Sanggenon D 81422-93-7 Sanggenon D, a natural product isolated and purified from the root bark of Morus alba L.
CSN20945 Robustaflavone 49620-13-5 Robustaflavone is a naturally occurring biflavanoid isolated from rhus succedanea, it can be act as an inhibitor of hepatitis B virus replication.
CSN12572 Rhoifolin 17306-46-6 Rhoifolin, a natural product isolated and purified from the leaves of Turpinia arguya Seem, hows monolithic proliferation inhibitory activities against Hela, A549 and MCF-7 cell lines, and may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4. It was found to efficiently block the enzymatic activity of SARS-CoV 3CLpro.
CSN20977 Quercetin-3-O-b-D-glucose-7-O-b-D-gentiobiosiden 60778-02-1 Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside is a natural product from desurainia sophia.
CSN11613 Ononin 486-62-4 Ononin is an isoflavonoid isolated and purified from the herb of Ononis natrix L., can inhibit the growth of pathogen such as Enterococcus sp., Enterobacter sp.
CSN20967 Nepitrin 569-90-4 Nepitrin is isolated from salvia plebeia R.Br. with antioxidant activity.
CSN22079 (2S,3S,4S,5R,6S)-6-((2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid 22688-79-5 Miquelianinis a metabolite of quercetin and a type of natural flavonoid which blocks β2-adrenergic signaling.
CSN21052 Methylophiopogonone B 74805-89-3 Methylophiopogonone B is a natural product from ophiopogon japonicus.
CSN14615 Licoisoflavone B 66056-30-2 Licoisoflavone B, a natural product isolated and purified from the roots of Glycyrrhiza aspera, exhibits antimutagenic activity against carcinogenic N-methyl-N-nitrosourea (MNU), it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.
CSN14847 Licoflavonol 60197-60-6 Licoflavonol, a natural product isolated and purified from the roots of Glycyrrhiza uralensis, exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC.
CSN14847 Licoflavonol 60197-60-6 Licoflavonol, a natural product isolated and purified from the roots of Glycyrrhiza uralensis, exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC.
CSN22080 Kuwanon A 62949-77-3 Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.) and inhibits nitric oxide production with IC50 of 10.5 μM.
CSN21038 Kushenol E 99119-72-9 Kushenol E can be found in the roots of sophora flavescens Ait. With significant antioxidant potentials.
CSN14822 Kazinol B 99624-27-8 Kazinol B, a natural product isolated and purified from the barks of Broussonetia papyrifera, inhibits the NO synthesis with an IC(50) of 21.6 mM, stimulates respiratory burst, is probably mediated by the synergism of PKC activation and [Ca2+]i elevation in rat neutrophils, stimulates Ca(2+) release from internal Ca(2+) store, probably through the sphingosine 1-phosphate and IP(3) signaling, activates external Ca(2+) influx mainly through a non-store-operated Ca(2+) entry (non-SOCE) pathway, and inhibits SOCE, probably attributable to a break in the Ca(2+) driven force of mitochondria.
CSN14611 Isochamaejasmin 93859-63-3 Isochamaejasmine, a natural product isolated and purified from the roots of Stellera chamaejasme Linn., has inhibition of NF-kappaB activation reversed the anti-apoptotic effect, shows antiplasmodial activity, with an IC(50) of 7.3+/-3.8 mM, but the selectivity was rather limited, and induces apoptosis in leukemia cells by inhibiting the activity of Bcl-2 family proteins, providing evidence for further studying the underlying anti-cancer mechanism of S.
CSN19926 Irigenin 548-76-5 Irigenin is a naturally occuring O-methylated isoflavone.
CSN16383 (S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one 520-33-2 Hesperetin is a flavanone extracted from the peel of citrus that exhibits inhibition of PDE4 and UGT. Hesperetin has antioxidative and anti-inflammatory effects as well. Hesperetin dose-dependently inhibited cleavage activity of the 3CLpro with IC50 value of 8.3μM in the cell-based assay.
CSN19988 Herbacetin 527-95-7 Herbacetin, a natural product isolated and purified from the herbs of Equisetum hyemale L. It was found to efficiently block the enzymatic activity of SARS-CoV 3CLpro.
CSN21670 Hematoxylin 1621-46-1 Hematoxylin is a nuclear stain, it oxidizes to haematein and form strongly colored complexes with metal ions ( Fe(III) and Al(III)).
CSN14614 Glabrene 60008-03-9 Glabrene, a natural product isolated and purified from the roots of Glycyrrhiza uralensis with estrogen-like activity, can stimulate DNA synthesis in human endothelial cells (ECV-304; E304) and has a bi-phasic effect on proliferation of human vascular smooth muscle cells (VSMC), exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, suggesting that it may serve as candidates for skin-lightening agents.
CSN14614 Glabrene 60008-03-9 Glabrene, a natural product isolated and purified from the roots of Glycyrrhiza uralensis with estrogen-like activity, can stimulate DNA synthesis in human endothelial cells (ECV-304; E304) and has a bi-phasic effect on proliferation of human vascular smooth muscle cells (VSMC), exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, suggesting that it may serve as candidates for skin-lightening agents.
CSN14269 Glabranine 41983-91-9 Glabranine, a natural product isolated and purified from the roots of Glycyrrhiza uralensis Fisch with antimicrobial activity, exerts a dose-dependent inhibitory effect in vitro on the dengue virus, they present 70% inhibition on the dengue virus at a concentration of 25 mM, and also shows significant activities on DPPH free radical with the IC50 of 240.20, 810.02 and 413.19 ug ml(-1), respectively.
CSN15096 Ficusin A 173429-83-9 Ficusin A is a natural product isolated and purified from the seeds of Psoralea corylifolia Linn.
CSN10136 Farrerol 24211-30-1 Farrerol is a natural product isolated and purified from the leaves of Rhododendron dauricum L.
CSN14844 Dehydroglyasperin D 517885-72-2 Dehydroglyasperin D, a natural product isolated and purified from the roots of Glycyrrhiza uralensis with anti-obesity, antioxidant, anti-aldose reductase, anticancer, anti-inflammator and strong ferric reducing activities, inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase, mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3, effectively scavenges DPPH, ABTS(+), and singlet oxygen radicals.
CSN14294 Dalbergioidin 30368-42-4 Dalbergioidin, a natural product isolated and purified from the roots of Parochetus communis with tyrosinase inhibitory activity with an IC50 of 20 mM, shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism, protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, and ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway.
CSN20844 Camelliaside A 135095-52-2 Camelliaside A is a flavonol triglycoside isolated from seeds of Camellia sinensis.
CSN19966 Apiin 26544-34-3 Apiin can inhibit iNOS expression and nitrite production in J774.A1 cells. It is a flavonoid isolated from the herbs of petroselinum crispum.
CSN10276 8-(5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 1617-53-4 Amentoflavone is an inhibitor of human UDP-glucuronosyltransferases with anti-inflammatory, antioxidative, and neuroprotective effects and it can be isolated from the seeds of Ginkgo biloba L. Amentoflavone inhibited SARS-CoV 3CL(pro) with IC50 value of 8.3μM.
CSN14057 (S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)chroman-4-one 53846-50-7 8-Prenylnaringenin is a phytoestrogen isolated and purified from the herbs of Humulus lupulus with the highest estrogenic activity, shows slight activity in this assay but significant activity by immunostaining, improves mitochondrial function, whereas a high dose of XN (5 µM) worsens the functionality of this organelle, and has more potent effects on promoting osteoblastic bone formation and inhibiting osteoclastic bone resorption by ERα instead of ERβ than the two classic phytoestrogens: genistein and daidzein.
CSN20926 5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 41440-05-5 8-Hydroxyapigenin is a flavone found in cupuaçu (Theobroma grandiflorum) and in the liverwort marchantia berteroana.
CSN25205 7-Hydroxyflavone 6665-86-7 7-Hydroxyflavone is a flavonoid isolated from M. indica, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway .
CSN14114 6-Demethoxytangeretin 6601-66-7 6-Demethoxytangeretin is a natural product isolated and purified from the herbs of Andrographis paniculata with anti-inflammatory activity.
CSN14300 (2S)-2'-Methoxykurarinone 270249-38-2 2'-Methoxykurarinone, a natural product isolated and purified from the roots of Sophora flavescens Ait.
CSN27563 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one 67604-48-2 (±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.
CSN14023 (-)-Epiafzelechin 24808-04-6 (-)-Epiafzelechin, a natural product isolated and purified from the herbs of Celastrus orbiculatus with antioxidant activity, exhibits various modes of action in suppressing HSV-2 multiplication, a dose-dependent inhibition on the COX activity with an IC50 value of 15 µM, and significant anti-inflammatory activity on carrageenin-induced mouse paw edema when the compound (100 mg/kg) was orally administrated at 1 h before carrageenin treatment.
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