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Flavonoids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN12074 | Theaflavin | 4670-05-7 | Theaflavin, a type of thearubigins, exhibits inhibition of xanthine oxidase enzyme and can scavenge various oxidation radicals with anti-oxidant and anti-tumor activities. It can be purified from the leaves of Camellia sinensis (L.) O. Kuntze. |
| CSN10060 | Tectochrysin | 520-28-5 | Tectochrysin, a natural product isolated and purified from the heartwood of Pinus strobus L., leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of STAT3 phosphorylation. |
| CSN14110 | Vexibinol | 97938-30-2 | Sophoraflavanone G is a small-molecule inhibitor of STAT signaling by targeting upstream signals of STATs that may have therapeutic potential for cancers caused by persistently activated STAT proteins. |
| CSN10165 | Scutellarin | 27740-01-8 | Scutellarin is an active flavonoid that shows anti-tumor activity and anti-proteasome action. It can be isolated from the root of Scutellaria baicalensis Georgi. |
| CSN13129 | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one dihydrate | 6151-25-3 | Quercetin Dihydrate inhibits various proteins including tyrosine protein kinase, mitochondrial phospholipase A2 and phosphodiesterases. It is a flavonoid with anticancer activity via suppressing type II estrogen receptors and blocking cell cycle progression. Quercetin could be found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine etc.. |
| CSN14128 | Phaseollidin | 37831-70-2 | Phaseollidin is a natural product with antimicrobial activity. |
| CSN11608 | Ombuoside | 20188-85-6 | Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays. |
| CSN13300 | Naringenin triacetate | 3682-04-0 | Naringenin triacetate is a natural product isolated and purified from the fruits of Citrus aurantium L. with a better binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1) when compared with the known inhibitors. |
| CSN11484 | 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one | 529-44-2 | Myricetin, a natural flavonoid isolated and purified from the root bark of Myrica cerifera L. with antioxidant and anti tumor properties, is an inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3Kγ with Kd of 0.17 μM. |
| CSN12274 | (S)-7-Hydroxy-2-(4-hydroxyphenyl)chroman-4-one | 578-86-9 | Liquiritigenin is an estrogenic compound which fuctions as a selective agonist of the estrogen receptor ERβ and an partial agonist of ERα. It also has choleretic effect. Liquiritigenin is a flavanone extracted from glycyrrhiza uralensis with antitumour action. |
| CSN11241 | Kaempferitrin | 482-38-2 | Kaempferitrin can activate insulin signaling pathway, phosphorylate Akt kinase and exert the transloocation of GLUT4, thus has antitumor, antidepressant and antidiabetic effects. Kaempferitrin is a natural product isolated and purified from the root of Kaempferia galangal L.. |
| CSN13127 | Jaceosidin | 18085-97-7 | Jaceosidin, a methylated trihydroxyflavone, can induce apoptosis in cancer cells via activating Bax and also could block signaling pathways related to inflammation. It is first isolated from the Compositae family. |
| CSN13968 | 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one | 38953-85-4 | Isovitexin, a natural product isolated and purified from the seeds of Vitex trifolia L., exhibits a potential antioxidant activity, shows a strong antihyperglycemic action, and inhibits α-glucosidase in vivo. |
| CSN11229 | Isosakuranetin | 480-43-3 | Isosakuranetin, a natural product isolated and purified from the fruits of Citrus aurantium L. with cytotoxic and fungicide properties and produces significant decrease in blood pressure. |
| CSN12677 | 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one | 480-19-3 | Isorhamnetin, a natural flavonol aglycone, can inhibit xanthine oxidase with IC50 of 400nM and stabilize β-catenin as well as up-regulate the Wnt signaling pathway. Isorhamnetin could also be act as an apoptosia inducer with antitumor activities. |
| CSN11174 | 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one | 482-35-9 | Isoquercitrinis can inhibit Wnt/β-catenin and activate the mitogen-activated protein kinase (MAPK) signalling pathway. It is a natural product isolated and purified from the herbs of Prunella vulgaris L. with a good effect of expectorant, cough, asthma and anti-tumoral activity. |
| CSN14005 | Isoginkgetin | 548-19-6 | Isoginkgetin is a MMP-9 inhibitor isolated and purified from the leaves of Ginkgo biloba L., also a Pre-mRNA Splicing inhibitor with IC 50 of 30 μM. |
| CSN13969 | Guaijaverin | 22255-13-6 | Guaijaverin, a natural product isolated and purified from the fruits of Psidium guajava Linn., has antioxidant activity and antibacterial activity against Strep. mutans. |
| CSN11100 | Glabridin | 59870-68-7 | Glabridin has many biological functions such as regulating the synthesis and activity of iNOS under high-glucose levels, significantly inhibiting free radicals generated during metabolism in the body, and protecting against oxidation-sensitive biomacromolecules (LDL, LDL, DNA) and cell walls. It is a natural product isolated and purified from the roots of Glycyrrhiza glabra L. with whitening and anti-aging activity. |
| CSN13948 | Eupatilin | 22368-21-4 | Eupatilin is an activiator of PPARα. It is a lipohilic flavonoid extracted from artemisia species with antioxidant, anti-tumor, and anti-inflammatory activities. |
| CSN10930 | Eriodictyol-7-O-glucoside | 38965-51-4 | Eriodictyol-7-O-glucoside, a natural product isolated and purified from the herbs of Dracocephalum rupestre, can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic, suggesting that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke. |
| CSN13970 | Engeletin | 572-31-6 | Engeletin, a natural product isolated and purified from the leaves of Engelhardtia roxburghiana Wall., may serve as a potential anti-inflammatory agent. Engeletin possesses potent inhibition of PGE2 release with IC50 values of 19.6 μg/mL. |
| CSN10830 | Diosmetin | 520-34-3 | Diosmetin is a bioflavonoid found in spearmint, oregano, and many other plants, and is an agonist of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity. |
| CSN13985 | Deguelin | 522-17-8 | Deguelin is a naturally occuring Akt inhibitor purified from the herbs of Derris robusta, which downregulates Akt phosphorylation and shows anticancer effect. |
| CSN10692 | Coptisine | 3486-66-6 | Coptisine is a protoberberine isoquinoline alkaloid isolated and purified from the herbs of Chelidonium majus L., which can increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2,3-dioxygenase . |
| CSN10135 | Cirsiliol | 34334-69-5 | Cirsiliol, a natural product, induces radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines. |
| CSN14022 | Chrysosplenetin | 603-56-5 | Chrysosplenetin, a natural product isolated and purified from the herbs of Laggera pterodonta, is a metabolic inhibitor of artemisinin. |
| CSN12252 | 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one | 480-40-0 | Chrysin, an analog of apigenin, demonstrates inhibition of aromatase and the phosphorylation of PLCY2 and PKC activities. It can be isolated from the blue passion flower (passiflora caerulea) with anti-inflammatory and anti-thrombotic activities etc.. |
| CSN12895 | (2R,2'R,3S,3'S,4S)-2,2'-Bis(3,4-dihydroxyphenyl)-[4,8'-bichromane]-3,3',5,5',7,7'-hexaol | 23567-23-9 | Cercosporamide is a potent and selective Mnk inhibitor, and an orally bioavailable antifungal agent, suppresses phosphorylation of eIF4E and exhibits antileukemic effects. |
| CSN12352 | Calycosin | 20575-57-9 | Calycosin, a phytoestrogen, is a partial agonist of ER and a calcium channel blocker. It also shows prevention of reperfusion injury. Calycosin can be isolated and purified from the herb of Astragalus membranaceus Bge. var. mongholicus with anti-oxidative activity. |
| CSN12351 | 5,7-Dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one | 491-80-5 | Biochanin A, a phytoestrogen from Trifolium pratense, is an inhibitor of PTK with IC50 of 91.5 μM. It also can be metabolized in vivo to genistein. |
| CSN10449 | Bilobetin | 521-32-4 | Bilobetin, a natural product isolated and purified from the leaves of Ginkgo biloba L., whose treatment ameliorates hyperlipidaemia, lipotoxicity and insulin resistance in rats by stimulating PPARα-mediated lipid catabolism. |
| CSN10380 | (S)-2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)chroman-4-one | 19879-30-2 | Bavachinin is an agonist of PPAR with EC50s of 4.0 µM, 8.1 µM, and 0.74 µM for α,β/δ, and γ respectively. It is a natural flavanone with anti-angiogenic effect. |
| CSN12275 | Dihydrokaempferol | 480-20-6 | Aromadendrin, a natural product isolated and purified from the bark of Eucalyptus calophylla, has anti-diabetic, anti-inflammatory, and antioxidant effects. |
| CSN12255 | 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 520-36-5 | Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM, it's a natural product isolated and purified from the root of Scutellaria indica L.. |
| CSN12350 | Acacetin | 480-44-4 | Acacetin shows inhibiton of the proliferation and induction apoptosis for cancer cells. It is a flavonoid purified from the bark of acacia farnesiana with anti-peroxidant, antiarthritic, and anti-inflammatory activities, |
| CSN10264 | Alpha-Naphthoflavone | 604-59-1 | 7,8-benzoflavone is a natural product isolated and purified from Passiflora, and it binds to human cytochrome P450 3A4 reveals complex fluorescence quenching. |
| CSN13014 | 7,3',4'-Trihydroxy-3-benzyl-2H-chromene | 1111897-60-9 | 7,3',4'-Trihydroxy-3-benzyl-2H-chromene, a natural product isolated and purified from the heartwoods of Caesalpinia sappan L., is a potential xanthine oxidase inhibitor. |
| CSN10156 | Nepetin | 520-11-6 | 6-Methoxyluteolin is a natural product isolated and purified from the flower of Chrysanthemum zawadskii var. latilobum with antioxidant activity and is also a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
| CSN13316 | 6,8-Diprenylgenistein | 51225-28-6 | 6,8-Diprenylgenistein is a natural product isolated and purified from the roots of Lupinus mutabilis with antimicrobial activity against Gram-negative and Gram-positive bacteria. |
| CSN13542 | 5-O-Demethylnobiletin | 2174-59-6 | 5-O-Demethylnobiletin, a flavonoid isolated from the peel of Citrus nobilis Lour., shows a certain inhibitory effect on DPP-IV enzyme. |
| CSN13042 | 7,3',4'-Tri-O-methylluteolin | 29080-58-8 | 5-Hydroxy-3',4',7-trimethoxyflavone, a natural product isolated and purified fromt Lippia nodiflora L., shows prominent inhibitory activity against soybean lipoxygenase. |
| CSN10169 | 7,4'-Dihydroxyflavone | 2196-14-7 | 4',7-Dihydroxyflavone is a natural product isolated and purified from the heartwood of Pterocarpus marsupium, with inhibitory activities against COX-2. |
| CSN12783 | (-)-gallocatechin | 3371-27-5 | (-)-Gallocatechin, a natural product isolated and purified from the wood of Acacia catechu (L.F.) Willd., has moderate affinity to the human cannabinoid receptor. |
| CSN12679 | (2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol | 490-46-0 | (-)-Epicatechin is a polyphenolic flavonoid that can act as an inhibitor of COX-1 (IC50 = 3.2 μM) and has activities of antioxidant, lipid-lowering and hypoglycemic, prevent cardiovascular diseases. (−)-Epicatechin is a 2R,3R stereoisomer of catechin. |
| CSN11587 | (2R,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate | 1257-08-5 | (-)-Epicatechin gallate, a polyphenol, is a apoptosis inducer of tumor cells that found in green tea. |
