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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN10240 | Aliskiren | 173334-57-1 | Aliskiren is a renin inhibitor with IC50 of 1.5 nM. |
| CSN10369 | 2-Ethoxy-1-((2'-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid | 147403-03-0 | Azilsartan is an orally available angiotensin II type 1 (AT1) receptor antagonist with IC50 value of 2.6 nM. |
| CSN10496 | Ambrisentan | 177036-94-1 | Ambrisentan is an oral, once-daily endothelin receptor antagonist that is selective for the endothelin type A receptor (IC50s = 0.251, 0.316, 0.398, 251, and 630 nM for rat preparations of heart, bladder, kidney, lung, and cerebral cortex, respectively). |
| CSN10124 | SEW2871 | 256414-75-2 | SEW2871 is a potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM. Cell-permeable and active in vivo. |
| CSN10095 | Mexiletine HCl | 5370-01-4 | Mexiletine HCl is a non-selective blocker of voltage-gated sodium channel. It blongs to the anti-arrhythmic compounds of class IB . |
| CSN10230 | Alacepril | 74258-86-9 | Alacepril is a long-acting, sulfhydryl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. |
| CSN10241 | Aliskiren hemifumarate | 173334-58-2 | Aliskiren hemifumarate is an inhibitor of renin with IC50 value of 1.5 nM. |
| CSN10277 | Amezinium methylsulfate | 30578-37-1 | Amezinium methylsulfate can stimulate α and β-1 receptors and inhibit noradrenaline and tyramine uptake, used as a sympathomimetic drug for the treatment of low blood pressure. |
| CSN10332 | Argatroban monohydrate | 141396-28-3 | Argatroban is an inhibitor of thrombin. |
| CSN10338 | Arotinolol | 68377-92-4 | Arotinolol is a blocker of both α- and β-receptor, and also acts as a β3 receptor agonist. It is used in the treatment of high blood pressure and essential tremor. |
| CSN10368 | Azelnidipine | 123524-52-7 | Azelnidipine is a dihydropyridine L-type calcium channel blocker and an antihypertensive. |
| CSN10481 | 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate | 157212-55-0 | Bosentan is an endothelin (ET) receptor antagonist of ET-A (Ki = 4.7 nM) and ET-B (Ki = 95 nM). |
| CSN10537 | Capadenoson | 544417-40-5 | Capadenoson is an oral active, potent and selective adenosine A1 receptor agonist. |
| CSN10639 | Cilnidipine | 132203-70-4 | Cilnidipine is a dual L- and N-type calcium channel blocker with antihypertensive, sympatholytic and neuroprotective activity. |
| CSN10445 | Bezafibrate | 41859-67-0 | Bezafibrate is the agonist of PPAR and the EC50 for PPAR⍺, PPARβ, PPARẟ is 50 , 20, and 60 nM respectively. It has hypolipidemic effect. |
| CSN10823 | (+)-cis-Diltiazem HCl | 33286-22-5 | Diltiazem HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. |
| CSN10166 | Trapidil | 15421-84-8 | Trapidil, a vasodilator and an antiplatelet drug, is also a PDGF antagonist that can inhibit the proliferation of the PDGF-producing glioma cells. |
| CSN10097 | Naftidrofuryl oxalate | 3200-06-4 | Naftidrofuryl oxalate is a drug used in the management of peripheral and cerebral vascular disorders as a vasodilator, enhance cellular oxidative capacity, and may also be a 5-HT2 receptor antagonist. |
| CSN10646 | Cinepazide Maleate | 26328-04-1 | Cinepazide Maleate is a maleate salt form of cinepazide which is a vasodilator. |
| CSN10677 | Clonidine HCl | 4205-91-8 | Clonidine HCl is a centrally-acting and brain-permeable α2-adrenergic agonist, which can induce a decrease in blood pressure. |
| CSN10763 | Delapril | 83435-66-9 | Delapril is an ACE inhibitor used as an antihypertensive drug. |
| CSN10307 | Anagrelide | 68475-42-3 | Anagrelide is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia), or overproduction of blood platelets, and also has been used in the treatment of chronic myeloid leukemia. It inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. |
| CSN10507 | Bunazosin hydrochloride | 52712-76-2 | Bunazosin HCl, is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug. |
| CSN10313 | Angiotensin II | 4474-91-3 | Angiotensin II human is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. |
| CSN10416 | Bepridil | 64706-54-3 | Bepridil is a long-acting calcium-blocking agent with significant anti-anginal activity. It produces significant coronary vasodilation and modest peripheral effects, and has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. |
| CSN10397 | Benidipine HCl | 91599-74-5 | Benidipine HCl is a dihydropyridine calcium channel blocker for the treatment of hypertension. |
| CSN10471 | Bivalirudin TFA | 1191386-55-6 | Bivalirudin trifluoroacetate is a reversible inhibitor of thrombin. It is a synthetic 20 residue peptide. |
| CSN10480 | Bosentan | 147536-97-8 | Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. |
| CSN10370 | Azimilide | 149908-53-2 | Azimilide is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. |
| CSN10287 | Amiodarone | 1951-25-3 | Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. |
| CSN10637 | Cilazapril | 88768-40-5 | Cilazapril is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. |
| CSN10544 | Moricizine | 31883-05-3 | Moricizine is an antiarrhythmia agent used primarily for ventricular rhythm disturbances. |
| CSN10326 | Aprotinin | 9087-70-1 | Aprotinin is an inhibitor of serine protease which can inhibit trypsin and chymotrypsin with Ki values of 0.06 pM and 9 nM. |
| CSN10675 | Methyldopa hydrate | 41372-08-1 | L-(-)-α-Methyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. |
| CSN10102 | Pentoxifylline | 6493-05-6 | Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor. |
| CSN10328 | Aranidipine | 86780-90-7 | Aranidipine is a long-acting, potent antihypertensive agent that works by blocking Ca2+ entry into cells. |
| CSN10342 | Angiotensin 1-7 | 51833-78-4 | Angiotensin 1-7 inhibits is purified canine angiotensin converting enzyme (ACE) activity with an IC50 of 0.65 μM. |
| CSN10638 | Cilazapril monohydrate | 92077-78-6 | Cilazapril is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. |
| CSN10667 | 2,2'-((Cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid) | 30299-08-2 | Clinofibrate is a HMG-CoA reductase inhibitor with IC50 value of 470 μM which can reduce plasma cholesterol levels and shows antihyperlipidemic effects. |
| CSN10692 | Coptisine | 3486-66-6 | Coptisine is a protoberberine isoquinoline alkaloid isolated and purified from the herbs of Chelidonium majus L., which can increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2,3-dioxygenase . |
| CSN10679 | Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate | 135046-48-9 | Clopidogrel is an inhibitor of platelet aggregation that is used to decrease the risk of myocardial infarction and stroke in patients known to have atherosclerosis. Clopidogrel has been linked to rare instances of idiosyncratic, clinically apparent acute liver injury. |
