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5-HT Receptor

5-HT Receptor

货号 产品名 CAS号 信息
CSN21267 YM348 372163-84-3 YM348 is a potent and orally active 5-HT2C receptor agonist, which shows a high affinity for cloned human 5-HT2C receptor (Ki: 0.89 nM).
CSN18999 Hypidone HCl 1339058-04-6 YL0919 is a dual 5-HT1A partial agonist and SSRI, producing antidepressant- and anxiolytic-like effects.
CSN18831 N-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cyclohexanecarboxamide Maleate 1092679-51-0 WAY-100635 fumarate is a potent and selective 5-HT receptor antagonist with IC50 of 0.95 nM.
CSN22124 WAY 163909 428868-32-0 WAY 163909 is a potent and selective 5-HT(2C) receptor agonist with Ki of 10.5±1.1 nM, respectively.
CSN19265 SB 242084 181632-25-7 SB-242084 is a 5-HT2C receptor antagonist (pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.
CSN19474 Sarpogrelate HCl 135159-51-2 Sarpogrelate HCl is an antagonist of both 5HT2A and 5-HT2B receptors, which can block serotonin-induced platelet aggregation and treat diabetes mellitus, Buerger's disease, Raynaud's disease, coronary artery disease, angina pectoris and atherosclerosis.
CSN20353 RS 67333 HCl 168986-60-5 RS-67333 HCl is a potent and highly selective 5-HT4 partial agonist, with pKi values of 8.7 at 5-HT4 sites in guinea pig striatum and > 6 at various other receptors, including 5-HT1A, 1D, 2A, 2C, D1, D2 and M1-3. It is also active in vivo, with an intrinsic activity relative to 5-HT of 0.5.
CSN20273 Ro60-0175 fumarate 169675-09-6 Ro 60-0175 is a 5HT2C receptor agonist.
CSN22178 PRX933 HCl 639029-42-8 PRX933 HCl is a 5-HT2c receptor agonist.
CSN19227 PRX-08066 maleate 866206-55-5 PRX-08066 maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model.
CSN20437 LP-211 1052147-86-0 P-211 is an a selective agonist of the serotonin 5-HT7 receptor with a Ki value of 0.58 nM at rat cloned 5-HT7 receptors, and > 300-fold selectivity over the 5-HT1A receptor.
CSN20577 Ocaperidone 129029-23-8 Ocaperidone is a benzisoxazole is an antagonist of both 5HT and D2 receptors.
CSN20313 Befiradol 208110-64-9 NLX-112 is a potent and efficacious serotonin 5-HT1A receptor agonist potentially for the treatment of drug-induced dyskinesia in patients.
CSN21278 Methiothepin mesylate 74611-28-2 Methiothepin mesylate is a potent and non-selective 5-HT2 receptor antagonist, with pKds of 7.10 (5-HT1A), 7.28 (5HT1B), 7.56 (5HT1C), 6.99 (5HT1D), 7.0 (5-HT5A), 7.8 (5-HT5B), 8.74 (5-HT6), and 8.99 (5-HT7), and pKis of 8.50 (5HT2A), 8.68 (5HT2B), and 8.35 (5HT2C).
CSN19837 (2,3-Dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol 139290-69-0 MDL 100151 is a selective 5-HT2A antagonist.
CSN19000 LY 344864 S-enantiomer 186544-27-4 LY 344864 S-enantiomer is the S-enantiomer of LY344864.
CSN22452 LY 344864 HCl 1217756-94-9 LY 344864 HCl is a selective 5-HT1F agonist with a Ki of 6 nM.
CSN21141 LY334370 182563-08-2 LY 334370 is a selective 5-HT1F receptor agonist (Ki=1.6nM). LY 334370 HCl displays antimigraine effects.
CSN21902 Lurasidone 367514-87-2 Lurasidone functions as an antagonist of the dopamine D2 and D3 receptors, the serotonin 5-HT2A and 5-HT7 receptors, the α2C-adrenergic receptor, and as a partial agonist of the serotonin 5-HT1A receptor.
CSN18968 Latrepirdine 2HCl 97657-92-6 Latrepirdine is an orally active,and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.
CSN18709 Flopropione 2295-58-1 Flopropione is both a 5-HT1A receptor antagonist and a COMT inhibitor as a spasmolytic or antispasmodic agent.
CSN20462 E-6837 528859-61-2 E-6837 is an orally active, 5-HT6 agonist developed in an attempt to create an anti-obesity medication.
CSN21976 Deschloroclozapine 1977-07-7 Dopamine serotonin antagonist-1 is antagonist of dopamine and serotonin receptor, the Kis for dopamine D1/D2/D4, and serotonin S2A/S2C/S3 are 200/2500/420 nM and 39/84/40 nM, respectively.
CSN21602 Desipramine HCl 58-28-6 Desipramine HCl is a dibenzazepine-derived tricyclic antidepressant which can selectively block reuptake of norepinephrine from the neural synapse, and also appear to impair serotonin transport.
CSN19266 CP-809101 479683-64-2 CP-809101 is a potent and selective 5-HT2C receptor agonist with pEC50 of 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors respectively.
CSN22722 BP 554 maleate 1221401-95-1 BP 554 Maleate is a selective 5-HT1A agonist.
CSN22714 BIMU 8 134296-40-5 BIMU 8 is a potent 5-HT4 receptor full agonist with KD of 77 nM and EC50 of 18 nM for wild type 5-HT4 receptors.
CSN19406 Azacyclonol 115-46-8 Azacyclonol is an ataractive agent, inhibiting shock-induced elevation of catecholamine levels in the brain and showing central depressant effects.
CSN20672 Aripiprazole Lauroxil 1259305-29-7 Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic. It is an N-acyloxymethyl prodrug of aripiprazole that is administered via intramuscular injection once every four to six weeks for the treatment of schizophrenia.
CSN22192 AR-A 2 220051-79-6 AR-A 2 is a selective 5-HT1B receptor antagonist, with high affinity to guinea pig cortex 5HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki=0.24 and 0.47 nM) and with 10-fold lower affinity to guinea pig 5-HT1D receptor (Ki=5 nM), and shows an EC50 of 4.5 nM for the guinea pig 5-HT1B receptor; AR-A 2 can be used in the research of depression and anxiety.
CSN22348 AP521 151227-08-6 AP521 is an agonist of human 5-HT1A receptor with an IC50 of 94 nM.
CSN19442 Alverine citrate 5560-59-8 Alverine Citrate is a 5-HT1A receptor antagonist with IC50 value of 101 nM.
CSN22674 Altanserin hydrochloride 1135280-78-2 Altanserin HCl is a potent and selective 5-HT2A receptor antagonist with Ki of 0.13 nM.
CSN22331 5-HT7 agonist 1 334974-31-1 5-HT7 agonist 1 is a selective 5-HT7 receptor agonist, with an IC50 of 222.93 nM, can be used for the 5-HT7 receptor related disease, such as CNS disorders.
CSN22190 5-HT4 antagonist 1 261766-73-8 5-HT4 antagonist 1 is a 5-HT4 receptor antagonist with a pKi of 9.6.
CSN21310 5-HT1A modulator 1 142477-34-7 5-HT1A modulator 1 displays very high affinities for the 5HT1A, adrenergic α1 and dopamine D2 receptor with IC50s of 2 ±0.3 nM, 10 ± 3 nM and 40 ±9 nM, respectively.
CSN22651 4F 4PP oxalate 144734-36-1 4F 4PP Oxalate is a selective 5-HT2A antagonist with Ki of 5.3 nM.
CSN22649 3-AQC 201216-42-4 3-AQC is a competitive 5-HT3 antagonist.
CSN22642 N-Phenylimidodicarbonimidic diamide hydrochloride 55-57-2 1-Phenylbiguanide HCl is a biguanide-class 5-HT3 agonist.
CSN22619 MCN-5652 96795-89-0 (±)-McN 5652 is a potent, orally active 5-HT uptake inhibitor and also inhibits noradrenalin and dopamine uptake in vitro.
CSN22639 (S)-WAY 100135 dihydrochloride 149007-54-5 (S)-WAY 100135 2HCl is a potent, selective 5-HT1A receptor antagonist with IC50 of 15 nM.
CSN50166 2-Benzyl-1-methyl-5-nonylpyrrolidin-3-ol 119463-16-0
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